Cell adhesion molecule Nr-CAM is over-expressed in human brain tumors

International Journal of Cancer

Volumn 76, Issue 4, 1998, Pages 451-458

  Sehgal, Anil ^a,d   Boynton, Alton L ^a   Young, Ronald F ^a,b   Vermeulen, Sandra S ^a,b   Yonemura, Kenneth S ^b   Kohler, Erik P ^a,c   Aldape, Hector C ^a   Simrell, Charles R ^a   Murphy, Gerald P ^a  

^a NORTHWEST HOSPITAL   (United States)

^b Northwest Neuroscience Institute   (United States)

^c Puget Sound Sage   (United States)

^d Pacifie Northwest Cancer Foundation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; COMPLEMENTARY DNA; TUMOR MARKER;

ARTICLE; ASTROCYTOMA; CELL ADHESION; CONTROLLED STUDY; GENE ISOLATION; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; MELANOMA; MENINGIOMA; NEUROBLASTOMA; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BASE SEQUENCE; BRAIN; BRAIN NEOPLASMS; CELL ADHESION MOLECULES; CELL ADHESION MOLECULES, NEURONAL; CLONING, MOLECULAR; HUMANS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; TUMOR CELLS, CULTURED;

EID: 0031960355     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19980518)76:4<451::AID-IJC1>3.0.CO;2-Q     Document Type: Article

References (24)

1. ALBELDA, S.M., Role of integrins and other cell adhesion molecules in tumor progression and metastasis. Lab. Invest., 68, 4-14 (1993).
2. BOGLER, O., HUANG, J.-J.S., KLEIHUES, P. and CAVENEE, W.K., The p53 gene and its role in human brain tumors. Glia. 15, 308-327 (1995).
3. FURNARI, F.B., HUANG, H.J. and CAVENEE, W.K., Genetics und malignant progression of human brain tumours. Cancer Surv., 25, 233-275 (1995).
4. GRUMET, M., NAURO, V., BURGOON, M.P., EDELMAN, G.M. and CUNNINGHAM, B.A., Structure of a new nervous system glycoprotein, NrCAM, and its relationship to subgroups of neural cell adhesion molecules, J. Cell Biol., 113, 1399-1412 (1991).
5. HORTSCH, M., The L1 family of neural cell adhesion molecules: old proteins performing new tricks. Neuron, 17, 587-593 (1996).
6. HSU, S.C., VOLPERT, O.V., STECK, P.A., MIKKELSEN, T., POLVERINI, P.J., RAO, S., CHOU, P. and BOUCK, N.P., Inhibition of angiogenesis in human glioblastomas by chromosome 10 induction of thrombospondin-1. Cancer Res., 56, 5684-5691 (1996).
7. JEN, J., HARPER, J.W., BIGNER, S.H., BIGNER, D.D., PAPADOPOULOS, N., MARKOWITZ, S., WILLSON, J.K.V., KINZLER, K.W. and VOGELSTEIN, B., Deletion of p16 and p15 genes in brain tumors. Cancer Res., 54, 6353-6358 (1994).
8. JOHNSON. J.P., Cell adhesion molecules of the immunoglobulin supergene family and their role in malignant transformation and progression to metastatic disease. Cancer Metastatic Rev., 10, 11-22 (1991).
9. KLEIHUES, P., SOYLEMEZOGLU, F., SCHAUBLE, B., SCHETTHAUER, B.W. and BURGER, P.C., Histopathology, classification, and grading of gliomas, Glia 15, 211-221 (1995).
10. LACHYANKAR, M.B., Ross, H.A., LITOFSKY, N.S., CONDON, P.J., QUESENBERRY, P.J. and RECHT, L.D., TrkA expression decreaes the in vivo aggressiveness of C6 glioma cells. Cancer Res., 57, 532-536 (1997).
11. LANE, R.P., CHEN, X.-N., YAMAKAWA, K., VIELMETTER, J., KORENBERG, J.R. and DREYER, W.J., Characterization of a highly conserved human homolog to the chicken neural cell surface protein bravo/NrCAM mat maps to chromosome band 7q31. Genomics. 35, 456-465 (1996).
12. LEDDA, M.F., ADRIS, S., BRAVO, A.I., KAIRIYAMA, C., BOVER, L., CHERNAJOVSKY, Y., MURDOH, J. and PODHAJCER, O.L., Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells. Nature (Med.), 3, 171-176 (1997).
13. LIANG, P., AVERBOUKH, L., KEYOMARSI, K., SAGER, R. and PARDEE, A.B., Differential display and cloning of messenger RNAs from human breast cancer versus mammary epithelial cells Cancer Res., 52, 6960-6968 (1992).
14. LIANG, P. and PARDEE, A.B., Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science. 257, 967-971 (1992).
15. LIBERMANN, T.A., NUSBAUM, H.R., RAZON, N., KRIS, R., LAX, I., SOREQ, H., WHITTLE, N., WATERFIELD, M.D., ULLRICH, A. and SCHLESSINGER, J., Amplification, enhanced expression and possible rearrangement ot EGF receptor gene in primary human brain tumours of glial origin. Nature (Lond.), 313, 144-147 (1985).
16. NISHIKAWA, R., JI, X.-D., HARMON, R.C., LAZAR, C.S., GILL, G.N., CAVENEE, W.K. and HUANG, H.-J.S., A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity. Proc. nat. Acad. Sci. (Wash)., 91, 7727-7731 (1994).
17. PARKER, S.L., TONG, T., BOLDEN, S. and WINGO, P.A., Cancer statistics. 1997. CA Cancer J. Clin., 47, 5-27 (1997).
18. SEHGAL, A., KEENER, C., BOYNTON, A.L., YOUNG, R.F., VERMEULEN, S.S., YONEMURA, K.S., KOHLER, E.P., ALDAPE, H.C., SIMRELL, C.R. and MURPHY, G.P., Characterization of C4-2 as a tumor-suppressor gene in human brain tumors. J. surg. Oncol., 64, 102-108 (1997a).
19. SEHGAL, A., KEENER, C., BOYNTON, A.L., YOUNG, R.F., VERMEULEN, S.S., YONEMURA, K.S., KOHLER, E.P., ALDAPE, H.C., SIMRELL, C.R. and MURPHY, G.P., Isolation and characterization of a novel gene from human glioblastoma multiforme tumor tissue. Int. J. Cancer. 71, 565-572 (1997b).
20. SEGHAL, A., PRESENTE, A., DUDUS, L. and ENGELHARDT, J.F., Isolation of differentially expressed cDN As during ferret tracheal development: application of differential display PCR. Exp. Lung Res., 22, 419-434 (1996).
21. THAPAR, K. and LAWS. E.R., Brain tumors. CA Cancer J. Clin., 43, 263-271 (1993).
22. VON DEIMLING, A., VON AMMON, K., SCHOENFELD, D., WlESTLER, O.D., SEIZINGER, B.R. and LOUIS, D.N., Subsets of glioblastoma multiforme defined by molecular genetic analysis. Brain Pathol., 3, 19-26 (1993).
23. WILKINSON, D.G., In situ hybridization, a practical approach, Oxford University Press. New York (1992).
24. XIE, S., HUANG, S., LUCA, M., GUTMAN, M.M., REICH, R., JOHNSON, J.P and BAR-ELI, M., Expression of MCAM/MUC18 by melanoma cells leads to increased tumor growth and metastasis. Proc. nat. Cancer Conf., 38, 533 (1997).