Marker selection for the transmission/disequilibrium test, in recently admixed populations

American Journal of Human Genetics

Volumn 62, Issue 3, 1998, Pages 703-712

  Kaplan, N L ^a   Martin, E R ^a,b   Morris, R W ^b,c   Weir, B S ^b  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c Analytical Sciences Inc   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTIC METHOD; ARTICLE; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC MARKER; GENETIC SELECTION; HUMAN; POPULATION GENETICS; PRIORITY JOURNAL;

EID: 0031958954     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/301760     Document Type: Article

References (20)

1. Bodmer WF (1986) Human genetics: the molecular challenge. In: Quantitative biology. Vol 1. Cold Spring Harb Symp Quant Biol 51:1-13
2. Briscoe D, Stephens JC, O'Brien SJ (1994) Linkage disequilibrium in admixed populations: applications in gene mapping. J Hered 85:59-63
3. Chakraborty R, Weiss KM (1988) Admixture as a tool for finding linked genes and detecting that difference from allelic association between loci. Proc Natl Acad Sci USA 85: 3071-3074
4. Copeman JB, Cucca F, Hearne CM, Cornall RJ, Reed PW, Ronningen KS, Undlien DE, et al (1995) Linkage disequilibrium mapping of type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31-33. Nat Genet 9:80-85
5. Cox NJ, Spielman RS (1989) The insulin gene and susceptibility to IDDM. Genet Epidemiol 6:65-69
6. Ewens WJ, Spielman RS (1995) The transmission/disequilibrium test: history, subdivision, and admixture. Am J Hum Genet 57:455-464
7. Jorde LB, Bamshad MJ, Watkins WS, Zenger R, Fraley AE, Krakowiak PA, Carpenter KD, et al (1995) Origins and affinities of modern humans: a comparison of mitochondrial and nuclear genetic data. Am J Hum Genet 57:523-538
8. Kaplan NL, Martin ER, Weir BS (1997) Power studies for the transmission/disequilibrium tests with multiple alleles. Am J Hum Genet 60:691-702
9. Maiste PJ, Weir BS (1995) A comparison of tests for independence in the FBI RFLP data bases. Genetica 96:125-138
10. McKeigue PM (1997) Mapping genes underlying ethnic differences in disease risk by linkage disequilibrium in recently admixed populations. Am J Hum Genet 60:188-196
11. Risch N (1992) Mapping genes for complex diseases with recently admixed populations. Am J Hum Genet Suppl 51: A13
12. Sawcer S, Jones HB, Feakes R, Gray J, Smalden N, Chataway J, Robertson N, et al (1996) A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22. Nat Genet 13:464-468
13. Sham PC, Curtis D (1995) An extended transmission/disequilibrium test (TDT) for multiallele marker loci. Ann Hum Genet 59:323-336
14. Sheffield VC, Weber JL, Buetow KH, Murray JC, Even DA, Wiles K, Gastier JM, et al (1995) A collection of tri- and tetranucleotide repeat markers used to generate high quality, high resolution human genome-wide linkage maps. Hum Mol Genet 4:1837-1844
15. Spielman RS, Ewens WJ (1996) The TDT and other family-based tests for linkage disequilibrium and association. Am J Hum Genet 59:983-989
16. Spielman RS, McGinnis RE, Ewens WJ (1993) Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 52:506-516
17. Stephens JC, Briscoe D, O'Brien SJ (1994) Mapping by admixture linkage disequilibrium in human populations: limits and guidelines. Am J Hum Genet 55:809-824
18. Tenvilliger JD (1995) A powerful likelihood method for the analysis of linkage disequilibrium between trait loci and one or more polymorphic marker loci. Am J Hum Genet 56: 777-787
19. Weir BS (1992) Independence tests for VNTR alleles defined as fixed bins. Genetics 130:873-887
20. Yuan B, Vaske D, Weber JL, Beck J, Sheffield VC (1997) Improved set of short-tandem-repeat polymorphisms for screening the human genome. Am J Hum Genet 60:459-460