The in vivo relationship between blood flow, contractions, pH and metabolites in the rat uterus

Pflugers Archiv European Journal of Physiology

Volumn 435, Issue 6, 1998, Pages 810-817

  Larcombe McDouall, Jacky B ^a   Harrison, Norma ^a   Wray, Susan ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Blood flow; Contraction; NMR; pH; Smooth muscle; Uterus

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; PHOSPHATE;

ANAEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PH; CONTROLLED STUDY; DOPPLER FLOWMETER; FLOW MEASUREMENT; IN VIVO STUDY; MUSCLE CONTRACTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTION; UTERUS BLOOD FLOW;

EID: 0031958897     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050588     Document Type: Article

References (31)

1. Abel MH, Hollingsworth M (1985) The potencies und selectivities of four calcium antagonists as inhibitors of uterine contractions in the rat in vivo. Br J Pharmacol 85: 263-269
2. Allen DG, Morris PG, Orchard CH, Pirolo JS (1985) A nuclear magnetic resonance study of metabolism in the ferret heart during hypoxia and inhibition of glycolysis. J Physiol (Lond) 361: 185-204
3. Brar HS, Platt LD, De Vore GR (1988) Qualitative assessment of maternal uterine and fetal umbilical artery blood flow and resistance in laboring patients by Doppler Velocimetry. Am J Obstet Gynecol 158: 952-956
4. Cady EB (1990) Clinical resonance spectroscopy. Plenum Press, London
5. Crichton CA, Taggart MJ, Wray S, Smith GL (1993) The effects of pH and inorganic phosphate on force production in α-toxin permeabilized isolated rat uterine smooth muscle. J Physiol (Lond) 465: 629-645
6. Dawson MJ, Raman J (1990) Uterine metabolism and energetics. In: Carsten MK, Miller JD (eds) Uterine function. Molecular and cellular aspects. Plenum Press, New York, pp 35-65
7. Dawson MJ, Wray S (1985) The effects of pregnancy and parturition on phosphorus metabolites in rat uterus studied by 31P nuclear magnetic resonance. J Physiol (Lond) 368: 19-31
8. 1H nuclear magnetic resonance spectroscopy. I. Methodology. J Cereb Blood Flow Melab 7: 199-206
9. Gregg DH, Fisher LC (1963) Blood supply to the heart. In: Hamilton WF (ed) Circulation, vol. 2 (Handbook of physiology series. Section 2) American Physiological Society. Bethseda. pp 1517-1584
10. Griess FC (1965) Effect of labour on uterine blood flow. Am J Obslet Gynecol 93: 917-923
11. Hamilton WF (1963) Circulation, vol. 2 (Handbook of physiology series. Section 2) American Physiological Society. Bethseda
12. Harrison N, Larcombe-McDouall JB, Earley L, Wray S (1994) An in vivo study of the effects of ischaemia on uterine contraction, intracellular pH and metabolites in the rat. J Physiol (Lond) 476: 349-354
13. 31P NMR investigation into the effects of repealed vascular occlusion on uterine metabolites, intracellular pH. and force in vivo. NMR Biomed 8: 28-32
14. 31P NMR spectroscopy. in vivo (abstract). J Physiol (Lond) 489: 133-134P
15. Harrison N, Larcombe-McDouall JB, Wray S (1995) The effects of graded reductions of uterine blood How on contractions and intrucellulur pH (pH,) (abstract). Society for Magnetic Resonance in Medicine, Nice meeting, vol. 2, 1667
16. Oliver JM, Kellie AE (1970) The effects of oestradiol on the acid soluble nucleotides of rat uterus. J Biochem 119: 187-191
17. Parratt J, Taggurt MJ, Wray S (1994) Abolition of contractions in the myometrium by acidification - in vitro. Lancet 344: 717-718
18. Phoenix J, Wray S (1994) Changes in human and rat uterine phosphoethanolamine and taurine with pregnancy and parturition. Exp Physiol 79: 601-604
19. Reimer KA, Jennings RB (1992) Myocardial ischaemia, hypoxia and infarction. In: Fozzard HA et al. (eds) The heart and cardiovascular system, 2nd edn. Raven Press, New York, pp 1875-1973
20. Standen NB (1992) Potassium channels, metabolism and muscle. Exp Physiol 77: 1-25
21. 2+. phosphorylation of myosin regulatory light chain and force in rat smooth muscle. J Physiol (Lond) 499: 485-496
22. Taggart MJ, Wray S (1993) Simultaneous measurement of intracellular pH and contraction in uterine smooth muscle. Pflügers Arch 423: 527-529 817
23. Taggart MJ, Wray S (1995) The effect of metabolic inhibition on rat uterine intracellular pH and its role in contractile failure. Pflügers Arch 430: 125-131
24. Thomas PJ, Fry CH (1996) The effects of cellular hypoxia on contraction and extracellular ion accumulation in isolated human detrusor smooth muscle. J Urol 155: 726-731
25. Vongsavan N, Matthews B (1993) Some aspects of the use of laser doppler flow meeters for recording tissue blood flow. Exp Physiol 78: 1-14
26. Wray S (1988) Smooth muscle intracellular pH: measurement, regulation, and function. Am J Physiol 254: C213-C225
27. Wray S (1990) The effects of metabolic inhibition on uterine metabolism and intracellular pH in the rat. J Physiol (Lond) 423: 411-423
28. Wray S (1993) Uterine contraction and physiological mechanisms of modulation. Am J Physiol 264: C1-C18
29. Wray S (1994) Hypoxia in the uterus. News Physiol Sci 9: 88-92
30. Wray S, Duggins K, Iles R, Nyman L, Osman VA (1992) The effects of metabolic inhibition and intracellular pH on rat uterine force production. Exp Physiol 77: 307-319
31. Wynn RM (1977) Biology of the uterus. Plenum Press, London