Expression of CEA and trophoblastic cell markers by lung carcinoma in association with histological characteristics and serum marker levels

European Journal of Cancer Prevention

Volumn 7, Issue 1, 1998, Pages 51-60

  Slodkowska, J ^a   Szturmowicz, M ^a   Rudzinski, P ^b   Giedronowicz, D ^a   Sakowicz, A ^a   Androsiuk, W ^a   Zakrzewska Rowinska, E ^a  

^a Department of Pathology ^*  (Poland)

^b Clinic of Chest Surgery   (Poland)

Author keywords

CEA; hCG; Lung cancer; Serum markers; SP1; Tumour markers

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CELL MARKER; CHORIONIC GONADOTROPIN BETA SUBUNIT; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; TUMOR MARKER;

ANTIGEN DETECTION; ANTIGEN EXPRESSION; ARTICLE; CANCER GRADING; CANCER STAGING; CELL DIFFERENTIATION; CONTROLLED STUDY; DIAGNOSTIC VALUE; FEMALE; HUMAN; HUMAN TISSUE; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ADENOCARCINOMA; ASPARTIC ENDOPEPTIDASES; CARCINOEMBRYONIC ANTIGEN; CARCINOMA, LARGE CELL; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SMALL CELL; CARCINOMA, SQUAMOUS CELL; CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MALE; NEOPLASM STAGING; PREGNANCY PROTEINS; TROPHOBLASTS; TUMOR MARKERS, BIOLOGICAL;

EID: 0031958503     PISSN: 09598278     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Acevedo HF, Krichevsky A, Campbell-Acevedo EA et al (1992). Flow cytometry method for the analysis of membrane-associated human chorionic gonadotropin, its subunits and fragments on human cancer cells. Cancer 69: 1818-28.
2. Acevedo HF, Campbell-Acevedo EA, Buffo MJ, Krichevsky A (1994). In vivo expression of membrane-associated human chorionic gonadotropin by cells isolated from cancerous human tissues. Proc Am Assoc Cancer Res 24: 27(abstract).
3. Acevedo HF, Tong JY, Hartsock RJ (1995). Human chorionic gonadotropin β subunit gene expression in cultured human fetal and cancer cells of different types and origins. Cancer 76: 1467-75.
4. Aroney RS, Dermody WC, Aldender P et al (1984). Multiple sequential biomarkers in monitoring patients with carcinoma of the lung. Cancer Treat Res 68: 859-66.
5. Boucher L, Yoneda K (1995). The expression of trophoblastic cell markers by lung carcinoma. 26: 1201-6.
6. Buccheri G, Violante B, Sartoris AM et al (1986). Clinical value of a multiple biomarker assay in patients with bronchogenic carcinoma. Cancer 57: 2389-96.
7. Buccheri GF, Ferrigno D, Vola F (1993). Carcinoembryonic antigen (CEA), tissue polypeptide antigen (TPA) and other prognostic indicators in the squamous cell carcinoma of the lung. Lung Cancer 10: 21-33.
8. Broniek A, Ochnio J, Roginska E, Kwiek S, Rowinska-Zakrzewska E (1986). Wystepowanie podwyzszonych poziomow podjednostek alfa i beta gonadotropiny kosmowkowej w surowicy chorych na pierwotnego raka pluca. Pneum Pol LIV 8: 348-53.
9. Chung CK, Zaino R, Stryker JA, O'Neill M, DeMuth WE (1982). Carcinoma of the lung: evaluation histological grade and factors influencing prognosis. Ann Thorac Surg 33: 599-604.
10. Ferrigno D, Buccheri G (1995). Clinical applications of serum markers for lung cancer. Resp Med 89: 587-97.
11. Ford CJH, Stokes HJ, Newmann CE (1981). Carcinoembryonic antigen and prognosis after medical surgery for lung cancer: immunocytochemical localisation and serum levels. Br J Cancer 44: 145-53.
12. Gropp C, Havemann K, Scheuer A (1980). Ectopic hormones in lung cancer patients at diagnosis and during therapy. Cancer 46: 347-354.
13. Gropp C, Sostman H, Luster W, Kalbfleisch H, Lehmann FG, Havemann K (1981). ACTH, β-lipotrophin, β-endorphin, βHCG, calcitonin, and CEA in lung tumor tissue. In CEA and andere Tumormarker (eds Uhlenbruck G. Wintzer G); Tumordiagnostik Verlag pp. 217-26.
14. Grudzinska JG, Coombees RC, Ratcliffe JG et al (1980). Circulating levels of pregnancy specific beta glycoprotein in patients with testicular, bronchogenic and breast carcinomas. Cancer 45: 102-3.
15. Harach HR, Skinner M, Gibbs AR (1983). Biological markers in human lung carcinoma: an immunopathological study of six antigens. Thorax 38: 937-41.
16. Hattori M, Fukase M, Yoshimi H et al (1978). Ectopic production of human chorionic gonadotropin in malignant tumors. Cancer 42: 2328-33.
17. Heyderman E, Chapman DV, Richardson TC (1982). Biological markers in lung cancer: an immunocytochemical approach. Cancer Detect Prev 5: 427-49.
18. Icard P, Regnard JF, Essomba A et al (1994). Preoperative carcinoembryonic antigen level as a prognostic indicator in resected primary lung cancer. Ann Thorac Surg 54: 811-4.
19. Kozlowicz-Gudzinska I, Pietraszek A, Kaminska J (1989). Wyjsciowe stezenia biologicznych markerow nowotworowych AFP (alfafetoproteiny), HCG (choriogonadotropiny kosmowkowej), SP1 (swoistego bialka ciazowego) w poszczegolnych typach i stopniach zaawansowania klinicznego raka pluca. Nowotwory 39: 162-5.
20. Lai R, Hsu H, Lu J, Ger L, Lai N (1996). Cyfra 21-1 enzyme-linked immunosorbent assay. Evaluation as a tumour marker in non-small cell lung cancer. Chest 109: 995-1000.
21. Miyake M, Ito M, Mitsuoka A et al (1987). Alpha-fetoprotein and human chorionic gonadotropin-producing lung cancer. Cancer 59: 227-32.
22. Moro D, Villemain D, Vuillez JP, Delord A, Brambilla C (1995). Cyfra 21-1 and SCC in non-small cell lung cancer. Lung Cancer 13: 169-76.
23. Mountain CF (1993). Lung cancer staging classification. Clin Chest Med 14: 43-51.
24. Niklinski J, Furman M, Laudanski J, Kozlowski M (1992). Prognostic value of pretreatment CEA, SCC-Ag and CA 19-9 levels in sera of patients with non-small cell lung cancer. Eur J Cancer Prev 1: 401-6.
25. Nishiyama T, Stolbach LL, Rule AH, De Lellis R. Inglis NR, Fishman WH (1980). Expression of oncodevelopmental markers (Regan isozyme, HCG, CEA) in tumor tisuues and uninvolved bronchial mucosa. An immunohistochemical study. Acta Histochem Cytochem 13: 245-53.
26. Picardo A, Torres A, Maestro M et al (1994). Quantitative analysis of carcinoembyonic antigen, squamous cell carcinoma antigen, CA 125, and CA 50 cytosolic content in non-small cell lung cancer. Cancer 73: 2305-11.
27. Poulakis N, Sarandakou A, Rizos D, Phocas I, Kontozoglou T (1991). Soluble interleukin-2 receptors and other markers in primary lung cancer. Cancer 68: 1045-9.
28. Regelson W (1995). Have we found the 'Definitive Cancer Biomarker'? Cancer 76: 1299-301.
29. Shinkai T, Saijo N, Tominaga K et al (1986). Serial plasma carcinoembryonic antigen measurement for monitoring patients with advanced lung cancer chemotherapy. Cancer 53: 1318-23.
30. Spinazzi A, Soresi E, Boffi R et al (1994). Evaluation of neuron-specific enolase, tissue polypeptide antigen, and carcinoembryonic antigen as markers for staging and monitoring response to therapy of lung cancer. Cancer Detect Prev 18: 209-20.
31. Sun NC, Edgington TD, Carpentier CL et al (1983). Immunohistochemical localization of carcinoembryonic antigen (CEA), CEA-S, and nonspecific cross-reacting antigen (NCA) in carcinomas of lung. Cancer 52: 1632-41.
32. Szturmowicz M, Wiatr E, Sakowicz A et al (1995). The role of human chorionic gonadotropin β subunit elevation in small-cell lung cancer patients. J Cancer Res Clin Oncol 121: 309-12.
33. Teglund S, Zhou G, Hammarstom S (1995). Characterization of cDNA encoding novel pregnance-specific glycoprotein variants. Biochem Biophys Res Comm 211: 656-64.
34. Vincent R, Chu TM, Lane WW (1979). The value of CEA in patients with carcinoma of the lung. Cancer 44: 685-91.
35. Wachner R, Wittekind Ch, von Kleist S (1984). Localisation of CEA, β-HCG, SP1 and keratin in the tissue of lung carcinomas. Virchows Arch (Pathol Anat) 402: 415-23.
36. Wilson TS, McDowell EM, McIntire KR, Trump BF (1981). Elaboration of human chorionic gonadotropin by lung tumors. Arch Pathol Lab Med 105: 169-73.
37. World Health Organization (1982). The World Health Organization histological typing of lung tumours. 2nd edition. Am J Clin Pathol 77: 123-36.