-
1
-
-
0028970047
-
Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9
-
BALDWIN, S. J., BLOOMER, J. C., SMITH, G. J., AYRTON, A. D., CLARKE, S. E. and CHENERY, R. J., 1995, Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9. Xenobiotica, 25, 261-270.
-
(1995)
Xenobiotica
, vol.25
, pp. 261-270
-
-
Baldwin, S.J.1
Bloomer, J.C.2
Smith, G.J.3
Ayrton, A.D.4
Clarke, S.E.5
Chenery, R.J.6
-
2
-
-
0016333916
-
Ethoxyresorufin : Direct fluorimetric assay of microsomal O-dealkylation which is preferentially induced by 3-methycholanthrene
-
BURKE, M. D. and MAYER, R. T., 1974, Ethoxyresorufin : direct fluorimetric assay of microsomal O-dealkylation which is preferentially induced by 3-methycholanthrene. Drug Metabolism and Disposition, 2, 583-588.
-
(1974)
Drug Metabolism and Disposition
, vol.2
, pp. 583-588
-
-
Burke, M.D.1
Mayer, R.T.2
-
3
-
-
0028362263
-
Characterization of the inhibition of P4501A2 by furafylline
-
CLARKE, S. E., AYRTON, A. D. and CHENERY, R. J., 1994, Characterization of the inhibition of P4501A2 by furafylline. Xenobiotica, 24, 517-526.
-
(1994)
Xenobiotica
, vol.24
, pp. 517-526
-
-
Clarke, S.E.1
Ayrton, A.D.2
Chenery, R.J.3
-
4
-
-
77957188094
-
A convenient method for the determination of hepatic lauric acid ω-oxidation based on solvent partition
-
GIERA, D. D. and VAN LIER, R. B. L., 1991, A convenient method for the determination of hepatic lauric acid ω-oxidation based on solvent partition. Fundamental and Applied Toxicology, 16, 348-355.
-
(1991)
Fundamental and Applied Toxicology
, vol.16
, pp. 348-355
-
-
Giera, D.D.1
Van Lier, R.B.L.2
-
5
-
-
0026082836
-
CDNA-expressed human cytochrome P-450s: A new age of molecular toxicology and human risk assessment
-
GONZALEZ, F. J., CRESPI, C. L. and GELBOIN, H. V., 1991, cDNA-expressed human cytochrome P-450s: a new age of molecular toxicology and human risk assessment. Mutation Research, 247, 113-127.
-
(1991)
Mutation Research
, vol.247
, pp. 113-127
-
-
Gonzalez, F.J.1
Crespi, C.L.2
Gelboin, H.V.3
-
6
-
-
0020507505
-
Determination of nitrazepam and temazepam in plasma by high performance liquid chromatography
-
HO, P., TRIGGS, E. J., HEAZLEWOOD, V. and BOURNE, D. W. A., 1983, Determination of nitrazepam and temazepam in plasma by high performance liquid chromatography. Therapeutic Drug Monitoring, 5, 303-307.
-
(1983)
Therapeutic Drug Monitoring
, vol.5
, pp. 303-307
-
-
Ho, P.1
Triggs, E.J.2
Heazlewood, V.3
Bourne, D.W.A.4
-
7
-
-
85081422446
-
In vitro metabolism of CL284,846 using subcellular fraction of human liver
-
submitted
-
KAWASHIMA, K., HOSOI, K., TAINAKA, H., SUBRAHMANYAM, V. V., NARUKE, T., SHIBA, T., KISHI, I. and WATABE, T., 1998, In vitro metabolism of CL284,846 using subcellular fraction of human liver. Drug Metabolism and Disposition (submitted).
-
(1998)
Drug Metabolism and Disposition
-
-
Kawashima, K.1
Hosoi, K.2
Tainaka, H.3
Subrahmanyam, V.V.4
Naruke, T.5
Shiba, T.6
Kishi, I.7
Watabe, T.8
-
8
-
-
0026324040
-
Bufuralol, dextromethorphan, and debrisoquine as prototype substrates for human P450IID6
-
KRONBACH, T., 1991, Bufuralol, dextromethorphan, and debrisoquine as prototype substrates for human P450IID6. Methods in Enzymology, 206, 509-517.
-
(1991)
Methods in Enzymology
, vol.206
, pp. 509-517
-
-
Kronbach, T.1
-
9
-
-
0003122802
-
Preparation and characterisation of microsomal fractions for studies of xenobiotic metabolism
-
edited by K. Snell and B. Mullock (Oxford: IRL)
-
LAKE, B. G., 1987, Preparation and characterisation of microsomal fractions for studies of xenobiotic metabolism. In Biochemical Toxicology : A Practical Approach, edited by K. Snell and B. Mullock (Oxford: IRL), pp. 183-215.
-
(1987)
Biochemical Toxicology : A Practical Approach
, pp. 183-215
-
-
Lake, B.G.1
-
10
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
LOWRY, O. H., ROSEBROUGH, N. J., FARR, A. L. and RANDALL, R. J., 1951, Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry, 193, 265-275.
-
(1951)
Journal of Biological Chemistry
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
11
-
-
0022344457
-
Mephenytoin hydroxylation polymorphism: Characterization of the enzymatic deficiency in liver microsomes from poor metabolizers phenotyped in vivo
-
MEIER, U. T., DAYER, P., MALÈ, P. J., KRONBACH, T. and MEYER, U.R., 1985, Mephenytoin hydroxylation polymorphism: characterization of the enzymatic deficiency in liver microsomes from poor metabolizers phenotyped in vivo. Clinical Pharmacology and Therapeutics, 38, 488-494.
-
(1985)
Clinical Pharmacology and Therapeutics
, vol.38
, pp. 488-494
-
-
Meier, U.T.1
Dayer, P.2
Malè, P.J.3
Kronbach, T.4
Meyer, U.R.5
-
12
-
-
0023630435
-
Determination of theophylline and its metabolites in plasma and urine by reverse-phase liquid chromatography using an amine modifier
-
NALINE, E., FLOUVAT, B., ADVENIER, C. and PAYS, M., 1987, Determination of theophylline and its metabolites in plasma and urine by reverse-phase liquid chromatography using an amine modifier. Journal of Chromatography, 419, 177-189.
-
(1987)
Journal of Chromatography
, vol.419
, pp. 177-189
-
-
Naline, E.1
Flouvat, B.2
Advenier, C.3
Pays, M.4
-
13
-
-
9044254525
-
P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
-
NELSON, D. R., KOYMANS, L., KAMATAKI, T., STEGEMAN, J. J., FEYEREISEN, R., WAXMAN, D. J., WATERMAN, M. R., GOTOH, O., COON, M. J., ESTABROOK, R. W., GUNSALUS, I. C. and NEBERT, D. W., 1996, P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics, 6, 1-42.
-
(1996)
Pharmacogenetics
, vol.6
, pp. 1-42
-
-
Nelson, D.R.1
Koymans, L.2
Kamataki, T.3
Stegeman, J.J.4
Feyereisen, R.5
Waxman, D.J.6
Waterman, M.R.7
Gotoh, O.8
Coon, M.J.9
Estabrook, R.W.10
Gunsalus, I.C.11
Nebert, D.W.12
-
14
-
-
0028858960
-
Cytochrome P450 inhibitors. Evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes
-
NEWTON, D. J., WANG, R.W. and LU, A. Y. H., 1995, Cytochrome P450 inhibitors. Evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes. Drug Metabolism and Disposition, 23, 154-158.
-
(1995)
Drug Metabolism and Disposition
, vol.23
, pp. 154-158
-
-
Newton, D.J.1
Wang, R.W.2
Lu, A.Y.H.3
-
15
-
-
78651165715
-
The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
-
OMURA, T. and SATO, R., 1964, The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. Journal of Biological Chemistry, 239, 2370-2378.
-
(1964)
Journal of Biological Chemistry
, vol.239
, pp. 2370-2378
-
-
Omura, T.1
Sato, R.2
-
16
-
-
0030056594
-
Specificity of substrate and inhibitor probes for cytochrome P450s: Evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes
-
ONO, S., HATANAKA, T., HOTTA, H., SATOH, T., GONZALEZ, F. J. and TSUTSUI, M., 1996, Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes. Xenobiotica, 26, 681-693.
-
(1996)
Xenobiotica
, vol.26
, pp. 681-693
-
-
Ono, S.1
Hatanaka, T.2
Hotta, H.3
Satoh, T.4
Gonzalez, F.J.5
Tsutsui, M.6
-
17
-
-
0030022629
-
An overview of current cytochrome P450 technology for assessing the safety and efficacy of new materials
-
PARKINSON, A., 1996a, An overview of current cytochrome P450 technology for assessing the safety and efficacy of new materials. Toxicologic Pathology, 24, 45-57.
-
(1996)
Toxicologic Pathology
, vol.24
, pp. 45-57
-
-
Parkinson, A.1
-
19
-
-
0026781890
-
Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes : Effects on coumarin, dicumarol, and testosterone oxidation
-
PEARCE, R., GREENWAY, D. and PARKINSON, A., 1992, Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes : effects on coumarin, dicumarol, and testosterone oxidation. Archives of Biochemistry and Biophysics, 298, 211-225.
-
(1992)
Archives of Biochemistry and Biophysics
, vol.298
, pp. 211-225
-
-
Pearce, R.1
Greenway, D.2
Parkinson, A.3
-
20
-
-
0025223625
-
Hydroxylation of chlorzoxazone as a specific probe for human cytochrome P-450IIE1
-
PETER, R., BÖCKER, R., BEAUNE, P. H., IWASAKI, M., GUENGERICH, F. P. and YANG, C. S., 1990, Hydroxylation of chlorzoxazone as a specific probe for human cytochrome P-450IIE1. Chemical Research in Toxicology, 3, 566-573.
-
(1990)
Chemical Research in Toxicology
, vol.3
, pp. 566-573
-
-
Peter, R.1
Böcker, R.2
Beaune, P.H.3
Iwasaki, M.4
Guengerich, F.P.5
Yang, C.S.6
-
21
-
-
0028059953
-
Comparison of levels of aldehyde oxidase with cytochrome P450 activities in human liver in vitro
-
RODRIGUES, A. D., 1994, Comparison of levels of aldehyde oxidase with cytochrome P450 activities in human liver in vitro. Biochemical Pharmacology, 48, 197-200.
-
(1994)
Biochemical Pharmacology
, vol.48
, pp. 197-200
-
-
Rodrigues, A.D.1
-
22
-
-
0023949862
-
Modulation of rabbit and human hepatic cytochrome P-450-cataly;ced steroid hydroxylations by α-naphthoflavone
-
SCHWAB, G. E., RAUCY, J. L. and JOHNSON, E. F., 1988, Modulation of rabbit and human hepatic cytochrome P-450-cataly;ced steroid hydroxylations by α-naphthoflavone. Molecular Pharmacology, 33, 493-499.
-
(1988)
Molecular Pharmacology
, vol.33
, pp. 493-499
-
-
Schwab, G.E.1
Raucy, J.L.2
Johnson, E.F.3
-
23
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals : Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
SHIMADA, T., YAMAZAKI, H., MIMURA, M., INUI, Y. and GUENGERICH, F. P., 1994, Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals : studies with liver microsomes of 30 Japanese and 30 Caucasians. Journal of Pharmacology and Experimental Therapeutics, 270, 414-423.
-
(1994)
Journal of Pharmacology and Experimental Therapeutics
, vol.270
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
Inui, Y.4
Guengerich, F.P.5
-
24
-
-
0023654735
-
Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450
-
SONDERFAN, A. J., ARLOTTO, M. P., DUTTON, D. R., MCKILLEN, S. K. and PARKINSON, A., 1987, Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450. Drug Metabolism and Disposition, 255, 27-41.
-
(1987)
Drug Metabolism and Disposition
, vol.255
, pp. 27-41
-
-
Sonderfan, A.J.1
Arlotto, M.P.2
Dutton, D.R.3
Mckillen, S.K.4
Parkinson, A.5
-
25
-
-
0028241592
-
Caffeine metabolism by human hepatic cytochromes P450: Contributions of 1A2, 2E1 and 3A isoforms
-
TASSANEEYAKUL, W., BIRKETT, D. J., MCMANUS, M. E., TASSANEEYAKUL, W., VERONESE, M. E., ANDERSSON, T., TUKEY, R. H. and MINERS, J. O., 1994, Caffeine metabolism by human hepatic cytochromes P450: contributions of 1A2, 2E1 and 3A isoforms. Biochemical Pharmacology, 47, 1767-1776.
-
(1994)
Biochemical Pharmacology
, vol.47
, pp. 1767-1776
-
-
Tassaneeyakul, W.1
Birkett, D.J.2
Mcmanus, M.E.3
Tassaneeyakul, W.4
Veronese, M.E.5
Andersson, T.6
Tukey, R.H.7
Miners, J.O.8
-
26
-
-
0031028518
-
Cooperativity in oxidations catalyzed by cytochrome P450 3A4
-
UENG, Y.-F., KUWABARA, T., CHUN, Y.-J. and GUENGERICH, F. P., 1997, Cooperativity in oxidations catalyzed by cytochrome P450 3A4. Biochemistry, 36, 370-381.
-
(1997)
Biochemistry
, vol.36
, pp. 370-381
-
-
Ueng, Y.-F.1
Kuwabara, T.2
Chun, Y.-J.3
Guengerich, F.P.4
-
27
-
-
0027756106
-
In vitro methods for assessing human hepatic drug metabolism: Their use in drug development
-
WRIGHTON, S. A., VANDENBRANDEN, M., STEVENS, J. C., SHIPLEY, L. A., RING, B. J., RETTIE, A. E. and CASHMAN, J. R., 1993, In vitro methods for assessing human hepatic drug metabolism: their use in drug development. Drug Metabolism Reviews, 25, 453-484.
-
(1993)
Drug Metabolism Reviews
, vol.25
, pp. 453-484
-
-
Wrighton, S.A.1
Vandenbranden, M.2
Stevens, J.C.3
Shipley, L.A.4
Ring, B.J.5
Rettie, A.E.6
Cashman, J.R.7
|