Effect of carbohydrate ingestion on adipose tissue lipolysis during long-lasting exercise in trained men

Journal of Applied Physiology

Volumn 84, Issue 5, 1998, Pages 1627-1632

  De Glisezinski, I ^a,b   Harant, I ^a   Crampes, F ^a,b   Trudeau, F ^c   Felez, A ^a   Cottet Emard J M ^d   Garrigues, M ^a,b   Riviere, D ^a,b  

^a CHU PURPAN   (France)

^b CHU RANGUEIL   (France)

^c UNIVERSITÉ DU QUÉBEC À TROIS RIVIÈRES   (Canada)

^d UNIVERSITÉ LYON 1   (France)

Author keywords

Adipose tissue microdialysis; Lipid mobilization; Sucrose

Indexed keywords

ADIPOSE TISSUE; ADULT; ARTICLE; CARBOHYDRATE INTAKE; CARBOHYDRATE METABOLISM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EXERCISE; FATTY ACID BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; INSULIN BLOOD LEVEL; LIPOLYSIS; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

EID: 0031957773     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1998.84.5.1627     Document Type: Article

References (31)

1. Abumrad, N. A., P. R. Perry, and R. R. Whitesell. Insulin antagonizes epinephrine activation of membrane transport of fatty acids. J. Biol. Chem. 261: 2999-3001, 1986.
2. Ahlborg, G., and P. Felig. Influence of glucose ingestion on fuel-hormone response during prolonged exercise. J. Appl. Physiol. 41: 683-688, 1976.
3. Arner, P. Impact of exercise on adipose tissue metabolism in humans. Int. J. Obes. 9, Suppl. 4: S18-S21, 1995.
4. Arner, P., and J. Bolinder. Microdialysis of adipose tissue. J. Intern. Med. 230: 381-386, 1991.
5. Arner, P., E. Kriegholm, P. Engfeld, and J. Bolinder. Adrenergic regulation of lipolysis in situ at rest and during exercise. J. Clin. Invest. 85: 893-898, 1990.
6. Barbe, P., V. Stich, J. Galitzky, M. Kunesova, V. Hainer, M. Lafontan, and M. Berlan. In vivo increase in β-adrenergic lipolytic response in subcutaneous adipose tissue of obese subjects submitted to a hypocaloric diet. J. Clin. Endocrinol. Metab. 82: 63-69, 1997
7. Boyd, A. E., S. R. Giamber, M. Mager, and H. E. Lebovitz. Lactate inhibition of lipolysis in exercising man. Metabolism. 23: 531-542, 1974.
8. Brooks, G. A., and J. Mercier. Balance of carbohydrate and lipid utilization during exercise: the "crossover" concept. J. Appl. Physiol. 76: 2253-2261, 1994.
9. Bülow, J. Human adipose tissue blood flow during prolonged exercise. III. Effect of β-adrenergic blockade, nicotinic acid and glucose infusion. Scand. J. Clin. Lab. Invest. 41: 415-424, 1981.
10. Bülow, J., and J. Madsen. Influence of blood flow on fatty acid mobilization from lipolytically active adipose tissue. Pflügers Arch. 390: 169-174, 1981.
11. Coggan, A. R., and E. F. Coyle. Metabolism and performance following carbohydrate ingestion late in exercise. Med. Sci. Sports Exerc. 21: 59-65, 1989.
12. Connet, R. J., T. E. J. Gayeski, and C. R. Honig. Lactate accumulation in fully aerobic working dog gracilis muscle. Am. J. Physiol. 246 (Heart Circ. Physiol. 15): H120-H128, 1984.
13. Costill, D. L., A. Bennett, G. Branam, and D. Eddy. Glucose ingestion at rest and during prolonged exercise. J. Appl. Physiol. 34: 59-65, 1973.
14. Crampes, F., M. Beauville, D. Rivière, and M. Garrigues. Effect of physical training in humans on the response of isolated fat cells to epinephrine. J. Appl. Physiol. 61: 25-29, 1986.
15. Cryer, P. E. Glucose counterregulation: prevention and correction of hypoglycemia in humans. Am. J. Physiol. 264 (Endocrinol. Metab. 27): E149-E155, 1993.
16. Felländer, G., B. Linde, and J. Bounder. Evaluation of the microdialysis ethanol technique for monitoring of subcutaneous adipose tissue blood flow in humans. Int. J. Obes. 20: 220-226, 1996.
17. Fredholm, B. B. The effect of lactate in canine subcutaneous adipose tissue in situ. Acta Physiol. Scand. 82: 249-261, 1971.
18. Galbo, H. Hormonal and Metabolic Adaptations to Exercise. Stuttgart, Germany: Thieme, 1983.
19. Galbo, H., N. J. Christensen, K. J. Mikines, B. Sonne, J. Hilsted, C. Hagen, and J. Fahrenkrug. The effect of fasting on the hormonal response to graded exercise. J. Clin. Endocrinol. Metab. 52: 1106-1112, 1981.
20. 2-adrenoceptors in regulating lipid mobilization from human adipose tissue. J. Clin. Invest. 91: 1997-2003, 1993.
21. Hirsh, I. B., J. C. Marker, L. J. Smith, R. Spina, C. A. Parvin, J. O. Holloszy, and P. E. Cryer. Insulin and glucagon in the prevention of hypoglycemia during exercise in humans. Am. J. Physiol. 260 (Endocrinol. Metab. 23): E695-E704, 1991.
22. Hodgetts, V., S. W. Coppack, K. N. Frayn, and T. D. R. Hocleaday. Factors controlling fat mobilization from humans subcutaneous adipose tissue during exercise. J. Appl. Physiol. 71: 445-451, 1991.
23. Jacobson, I., M. Sandberg, and A. Hamberger. Mass transfer in brain dialysis devices - a new method for the estimation of extracellular amino-acid concentration. J. Neurosci. Methods 15: 263-268, 1985.
24. Kather, H., F. Schroder, and B. Simon. Microdetermination of glycerol using bacterial NADH-linked luciferase. Clin. Chim. Acta 120: 295-300, 1982.
25. Koubi, H. E., D. Desplanches, C. Gabrielle, J. M. Cottet-Emard, B. Sempore, and R. J. Favier. Exercise endurance and fuel utilization: a reevaluation of the effects of fasting. J. Appl. Physiol. 70: 1337-1343, 1991.
26. Manganiello, V., and M. Vaughan. An effect of insulin in cyclic adenosine 3′5, monophosphate phosphodiesterase activity in fat cells. J. Biol. Chem. 248: 7164-7170, 1973.
27. Massicote, D., F. Péronnet, E. Adopo, G. R. Brisson, and C. Hillaire-Marcel. Metabolic availability of oral glucose during exercise: a reassessment. Metabolism 41: 1284-1290, 1992.
28. Péquignot, J.-M., L. Peyrin, and G. Pérès. Catecholamine-fuel interrelationships during exercise in fasting men. J. Appl. Physiol. 48: 109-113, 1980.
29. Satabin, P., P. Portero, G. Defer, J. Bricourt, and C. Y. Guezennec. Metabolic and hormonal responses to lipid and carbohydrate diets during exercise in man. Med. Sci. Sports Exerc. 19: 218-223, 1987.
30. Sidossis, L. S., and R. R. Wolfe. Glucose and insulin-induced inhibition of fatty acid oxidation: the glucose-fatty acid cycle reversed. Am. J. Physiol. 270 (Endocrinol. Metab. 33): E733-E738, 1996.
31. Wasserman, D. H., D. B. Lacy, R. E. Goldstein, P. E. Williams, and A. D. Cherrington. Exercise-induced fall in insulin and the increase in fat metabolism during prolonged exercise. Diabetes 38: 484-490, 1989.