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Volumn 79, Issue 4, 1998, Pages 859-864

Effect of a synthetic factor Xa inhibitor, YM-60828, on blood vessel patency in combination with a thrombolytic agent and on blood loss from the operation site in a rat model of arterial thrombosis

Author keywords

[No Author keywords available]

Indexed keywords

ARGATROBAN; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING INHIBITOR; FIBRINOLYTIC AGENT; HEPARIN; N [4 [(1 ACETIMIDOYL 4 PIPERIDYL)OXY]PHENYL] N [(7 AMIDINO 2 NAPHTHYL)METHYL]SULFAMOYL]ACETIC ACID DIHYDROCHLORIDE; PLASMINOGEN ACTIVATOR; SHIMIZU; UNCLASSIFIED DRUG; [N [4 [(1 ACETIMIDOYL 4 PIPERIDYL)OXY]PHENYL] N [(7 AMIDINO 2 NAPHTHYL)METHYL]SULFAMOYL]ACETIC ACID;

EID: 0031957619     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1615078     Document Type: Article
Times cited : (22)

References (36)
  • 1
    • 0026073346 scopus 로고
    • Requirement of heparin for arterial and venous thrombolysis with recombinant tissue-type plasminogen activator
    • Rapold HJ, Lu HR, Wu ZM, Nijs H, Collen D. Requirement of heparin for arterial and venous thrombolysis with recombinant tissue-type plasminogen activator. Blood 1991; 77: 1020-4.
    • (1991) Blood , vol.77 , pp. 1020-1024
    • Rapold, H.J.1    Lu, H.R.2    Wu, Z.M.3    Nijs, H.4    Collen, D.5
  • 2
    • 0023230458 scopus 로고
    • Heparin requirement in tissue-type plasminogen activator-induced experimental coronary thrombolysis: Comparison with urokinase-induced coronary thrombolysis
    • Susawa T, Yui Y, Hattori R, Takahashi M, Aoyama T, Takatsu Y, Sakaguchi K, Yui N, Kawai C. Heparin requirement in tissue-type plasminogen activator-induced experimental coronary thrombolysis: comparison with urokinase-induced coronary thrombolysis. Jpn Circ J 1987; 51: 431-5.
    • (1987) Jpn Circ J , vol.51 , pp. 431-435
    • Susawa, T.1    Yui, Y.2    Hattori, R.3    Takahashi, M.4    Aoyama, T.5    Takatsu, Y.6    Sakaguchi, K.7    Yui, N.8    Kawai, C.9
  • 3
    • 0026099431 scopus 로고
    • Relative efficacy of antithrombin compared with antiplatelet agents in accelerating coronary thrombolysis and preventing early reocclusion
    • Haskel EJ, Prager NA, Sobel BE, Abendschein DR. Relative efficacy of antithrombin compared with antiplatelet agents in accelerating coronary thrombolysis and preventing early reocclusion. Circulation 1991; 83: 1048-56.
    • (1991) Circulation , vol.83 , pp. 1048-1056
    • Haskel, E.J.1    Prager, N.A.2    Sobel, B.E.3    Abendschein, D.R.4
  • 4
    • 0025146426 scopus 로고
    • Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin Ill-independent inhibitors
    • Weitz JI, Hudoba M, Massel D, Maraganore J, Hirsh J. Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin Ill-independent inhibitors. J Clin Invest 1990; 86: 385-91.
    • (1990) J Clin Invest , vol.86 , pp. 385-391
    • Weitz, J.I.1    Hudoba, M.2    Massel, D.3    Maraganore, J.4    Hirsh, J.5
  • 5
    • 0024670167 scopus 로고
    • Fibrin monomer protects thrombin from inactivation by heparin-antithrombin III: Implications for heparin efficacy
    • Hogg PJ, Jackson CM. Fibrin monomer protects thrombin from inactivation by heparin-antithrombin III: implications for heparin efficacy. Proc Natl Acad Sci USA 1989; 86: 3619-23.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3619-3623
    • Hogg, P.J.1    Jackson, C.M.2
  • 6
    • 0027959329 scopus 로고
    • Effects of the synthetic thrombin inhibitor argatroban on fibrin- Or clot-incorporated thrombin: Comparison with heparin and recombinant hirudin
    • Berry CN, Girardot C, Lecoffre C, Lunven C. Effects of the synthetic thrombin inhibitor argatroban on fibrin-or clot-incorporated thrombin: comparison with heparin and recombinant hirudin. Thromb Haemost 1994; 72: 381-6.
    • (1994) Thromb Haemost , vol.72 , pp. 381-386
    • Berry, C.N.1    Girardot, C.2    Lecoffre, C.3    Lunven, C.4
  • 7
    • 0028037517 scopus 로고
    • Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndromes
    • GUSTO IIA Investigator. Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndromes. Circulation 1994; 90: 1631-7.
    • (1994) Circulation , vol.90 , pp. 1631-1637
  • 8
    • 0014437059 scopus 로고
    • Investigation of the apparent thrombogenicity of thrombin
    • Yin ET, Wessler S. Investigation of the apparent thrombogenicity of thrombin. Thromb Diath Haemorrh 1968; 20: 465-8.
    • (1968) Thromb Diath Haemorrh , vol.20 , pp. 465-468
    • Yin, E.T.1    Wessler, S.2
  • 9
    • 0027295989 scopus 로고
    • Antithrombotic activity of recombinant tick anticoagulant peptide and heparin in a rabbit model of venous thrombosis
    • Fioravanti C, Burkholder D, Francis B, Siegl PK, Gibson RE. Antithrombotic activity of recombinant tick anticoagulant peptide and heparin in a rabbit model of venous thrombosis. Thromb Res 1993; 71: 317-24.
    • (1993) Thromb Res , vol.71 , pp. 317-324
    • Fioravanti, C.1    Burkholder, D.2    Francis, B.3    Siegl, P.K.4    Gibson, R.E.5
  • 10
    • 0029111442 scopus 로고
    • DX-9065a, an orally active, specific inhibitor of factor Xa, inhibits thrombosis without affecting bleeding time in rats
    • Hara T, Yokoyama A, Tanaba K, Ishihara H, Iwamoto M. DX-9065a, an orally active, specific inhibitor of factor Xa, inhibits thrombosis without affecting bleeding time in rats. Thromb Haemost 1994; 74: 635-9.
    • (1994) Thromb Haemost , vol.74 , pp. 635-639
    • Hara, T.1    Yokoyama, A.2    Tanaba, K.3    Ishihara, H.4    Iwamoto, M.5
  • 12
    • 0028114111 scopus 로고
    • Effects of DX-9065a, an orally active, newly synthesized and specific inhibitor of factor Xa, against experimental disseminated intravascular coagulation in rats
    • Yamazaki M, Asakura H, Aoshima K, Saito M, Jokaji H, Uotani C, Kumabashiri I, Morishima E, Ikeda T, Matsuda T. Effects of DX-9065a, an orally active, newly synthesized and specific inhibitor of factor Xa, against experimental disseminated intravascular coagulation in rats. Thromb Haemost 1994; 72: 393-6.
    • (1994) Thromb Haemost , vol.72 , pp. 393-396
    • Yamazaki, M.1    Asakura, H.2    Aoshima, K.3    Saito, M.4    Jokaji, H.5    Uotani, C.6    Kumabashiri, I.7    Morishima, E.8    Ikeda, T.9    Matsuda, T.10
  • 14
    • 0031964032 scopus 로고    scopus 로고
    • YM-60828, a newly synthesized potent and selective factor Xa inhibitor, exerts its antithrombotic effect with little prolongation of bleeding time
    • Sato K, Kawasaki T, Hisamichi N, Taniuchi Y, Hirayama F, Koshio H, Matsumoto Y. YM-60828, a newly synthesized potent and selective factor Xa inhibitor, exerts its antithrombotic effect with little prolongation of bleeding time. Br J Pharmacol 1998; 123: 92-6.
    • (1998) Br J Pharmacol , vol.123 , pp. 92-96
    • Sato, K.1    Kawasaki, T.2    Hisamichi, N.3    Taniuchi, Y.4    Hirayama, F.5    Koshio, H.6    Matsumoto, Y.7
  • 15
    • 0031588348 scopus 로고    scopus 로고
    • The separation of YM-60828, a newly synthesized potent and selective factor Xa inhibitor, between the antithrombotic effect and the prolongation effect of bleeding time in comparison with conventional anticoagulant agents
    • Sato K, Kawasaki T, Taniuchi Y, Hirayama F, Koshio H, Matsumoto Y. The separation of YM-60828, a newly synthesized potent and selective factor Xa inhibitor, between the antithrombotic effect and the prolongation effect of bleeding time in comparison with conventional anticoagulant agents. Eur J Pharmacol 1997; 339: 141-6.
    • (1997) Eur J Pharmacol , vol.339 , pp. 141-146
    • Sato, K.1    Kawasaki, T.2    Taniuchi, Y.3    Hirayama, F.4    Koshio, H.5    Matsumoto, Y.6
  • 16
    • 0031933443 scopus 로고    scopus 로고
    • Comparative studies of an orally-active factor Xa inhibitor, YM-60828, with other antithrombotic agents in a rat model of arterial thrombosis
    • Kawasaki T, Sato K, Sakai Y, Hirayama F, Koshio H, Taniuchi Y, Matsumoto Y. Comparative studies of an orally-active factor Xa inhibitor, YM-60828, with other antithrombotic agents in a rat model of arterial thrombosis. Thromb Haemost 1998; 79: 410-6.
    • (1998) Thromb Haemost , vol.79 , pp. 410-416
    • Kawasaki, T.1    Sato, K.2    Sakai, Y.3    Hirayama, F.4    Koshio, H.5    Taniuchi, Y.6    Matsumoto, Y.7
  • 17
    • 0027427576 scopus 로고
    • Thrombolytic activity of a novel modified tissue-type plasminogen activator, YM866, in a canine model of coronary artery thrombosis
    • Kawasaki T, Katoh M, Kaku S, Gushima H, Takenaka T, Yui Y, Kawai C. Thrombolytic activity of a novel modified tissue-type plasminogen activator, YM866, in a canine model of coronary artery thrombosis. Jpn J Pharmacol 1993; 63: 9-16.
    • (1993) Jpn J Pharmacol , vol.63 , pp. 9-16
    • Kawasaki, T.1    Katoh, M.2    Kaku, S.3    Gushima, H.4    Takenaka, T.5    Yui, Y.6    Kawai, C.7
  • 18
    • 0027369933 scopus 로고
    • Experimental model of carotid artery thrombosis in rats and the thrombolytic activity of YM866, a novel modified tissue-type plasminogen activator
    • Kawasaki T, Kawamura S, Katoh S, Takenaka T. Experimental model of carotid artery thrombosis in rats and the thrombolytic activity of YM866, a novel modified tissue-type plasminogen activator. Jpn J Pharmacol 1993; 63: 135-40.
    • (1993) Jpn J Pharmacol , vol.63 , pp. 135-140
    • Kawasaki, T.1    Kawamura, S.2    Katoh, S.3    Takenaka, T.4
  • 19
    • 0015247211 scopus 로고
    • Experimental thrombosis in rats with continuous registration
    • Hladovec J. Experimental thrombosis in rats with continuous registration. Thromb Diath Haemorrh 1971; 26: 407-10.
    • (1971) Thromb Diath Haemorrh , vol.26 , pp. 407-410
    • Hladovec, J.1
  • 21
    • 0018168136 scopus 로고
    • Comparison of antithrombotic activity of heparin, ASA, sulfinpyrazone and VK744 in a rat model of arterial thrombosis
    • Philip RB, Francey I, Warren BA. Comparison of antithrombotic activity of heparin, ASA, sulfinpyrazone and VK744 in a rat model of arterial thrombosis. Haemostasis 1978; 7: 282-93.
    • (1978) Haemostasis , vol.7 , pp. 282-293
    • Philip, R.B.1    Francey, I.2    Warren, B.A.3
  • 22
    • 0026652586 scopus 로고
    • Selective factor Xa inhibition by recombinant antistasin prevents vascular graft thrombosis in baboon
    • Schaffer LW, Davidson JT, Vlasuk GP, Dunwiddie CT, Siegl PK. Selective factor Xa inhibition by recombinant antistasin prevents vascular graft thrombosis in baboon. Arterioscler Thromb 1992; 12: 879-85.
    • (1992) Arterioscler Thromb , vol.12 , pp. 879-885
    • Schaffer, L.W.1    Davidson, J.T.2    Vlasuk, G.P.3    Dunwiddie, C.T.4    Siegl, P.K.5
  • 23
    • 0030022915 scopus 로고    scopus 로고
    • Comparison of sustained antithrombotic effects of inhibitors of thrombin and factor Xa in experimental thrombosis
    • Biemond BJ, Friederich PW, Levi M, Vlasuk GP, Buller HR, ten Cate JW. Comparison of sustained antithrombotic effects of inhibitors of thrombin and factor Xa in experimental thrombosis. Circulation 1996; 93: 153-60.
    • (1996) Circulation , vol.93 , pp. 153-160
    • Biemond, B.J.1    Friederich, P.W.2    Levi, M.3    Vlasuk, G.P.4    Buller, H.R.5    Ten Cate, J.W.6
  • 24
    • 0030586091 scopus 로고    scopus 로고
    • Antithrombotic actions of selective inhibitors of blood coagulation factor Xa in rat models of thrombosis
    • Wong PC, Grain EJ Jr., Nguan O, Watson CA, Racanelli A. Antithrombotic actions of selective inhibitors of blood coagulation factor Xa in rat models of thrombosis. Thromb Res 1996; 83: 117-26.
    • (1996) Thromb Res , vol.83 , pp. 117-126
    • Wong, P.C.1    Grain Jr., E.J.2    Nguan, O.3    Watson, C.A.4    Racanelli, A.5
  • 25
    • 0030614665 scopus 로고    scopus 로고
    • The antithrombotic effect of synthetic low molecular weight human factor Xa inhibitor. DX-9065a, on He-Ne laser-induced thrombosis in rat mesenteric microvessels
    • Yamashita T, Tsuji T, Matsuoka A, Giddings JC, Yamamoto J. The antithrombotic effect of synthetic low molecular weight human factor Xa inhibitor. DX-9065a, on He-Ne laser-induced thrombosis in rat mesenteric microvessels. Thromb Res 1996; 85: 45-51.
    • (1996) Thromb Res , vol.85 , pp. 45-51
    • Yamashita, T.1    Tsuji, T.2    Matsuoka, A.3    Giddings, J.C.4    Yamamoto, J.5
  • 26
    • 0026556210 scopus 로고
    • Acceleration of recombinant tissue-type plasminogen activator-induced reperfusion and prevention of reocclusion by recombinant antistasin, a selective factor Xa inhibitor, in a canine model of femoral arterial thrombosis
    • Mellott MJ, Holahan MA, Lynch JJ, Vlasuk GP, Dunwiddie CT. Acceleration of recombinant tissue-type plasminogen activator-induced reperfusion and prevention of reocclusion by recombinant antistasin, a selective factor Xa inhibitor, in a canine model of femoral arterial thrombosis. Circ Res 1992; 70: 1152-60.
    • (1992) Circ Res , vol.70 , pp. 1152-1160
    • Mellott, M.J.1    Holahan, M.A.2    Lynch, J.J.3    Vlasuk, G.P.4    Dunwiddie, C.T.5
  • 27
    • 0026558347 scopus 로고
    • Conjunctive enhancement of enzymatic thrombolysis and prevention of thrombotic reocclusion with the selective factor Xa inhibitor, tick anticoagulant peptide
    • Sitko GR, Ramjit DR, Stabilito II, Lehman D, Lynch JJ, Vlasuk GP. Conjunctive enhancement of enzymatic thrombolysis and prevention of thrombotic reocclusion with the selective factor Xa inhibitor, tick anticoagulant peptide. Circulation 1992; 85: 805-15.
    • (1992) Circulation , vol.85 , pp. 805-815
    • Sitko, G.R.1    Ramjit, D.R.2    Stabilito, I.I.3    Lehman, D.4    Lynch, J.J.5    Vlasuk, G.P.6
  • 28
    • 0027161780 scopus 로고
    • Enhancement of recombinant tissue plasminogen activator-induced reperfusion by recombinant tick anticoagulant peptide, a selective factor Xa inhibitor, in a canine model of femoral arterial thrombosis
    • Mellott MJ, Stranieri MT, Sitko GR, Stabilito II, Lynch JJ, Vlasuk GP. Enhancement of recombinant tissue plasminogen activator-induced reperfusion by recombinant tick anticoagulant peptide, a selective factor Xa inhibitor, in a canine model of femoral arterial thrombosis. Fibrinolysis 1993; 7: 195-202.
    • (1993) Fibrinolysis , vol.7 , pp. 195-202
    • Mellott, M.J.1    Stranieri, M.T.2    Sitko, G.R.3    Stabilito, I.I.4    Lynch, J.J.5    Vlasuk, G.P.6
  • 29
    • 0029848088 scopus 로고    scopus 로고
    • Comparative study of a mutant tissue-type plasminogen activator, YM866, with a tissue-type plasminogen activator in a canine model of femoral arterial thrombosis
    • Kawasaki T, Kaku S, Sakai Y, Takenaka T. Comparative study of a mutant tissue-type plasminogen activator, YM866, with a tissue-type plasminogen activator in a canine model of femoral arterial thrombosis. J Pharm Pharmacol 1996; 48: 1041-8.
    • (1996) J Pharm Pharmacol , vol.48 , pp. 1041-1048
    • Kawasaki, T.1    Kaku, S.2    Sakai, Y.3    Takenaka, T.4
  • 32
    • 0029077090 scopus 로고
    • VCL, an antagonist of the platelet GPIb receptor, markedly inhibits platelet adhesion and intimal thickening after balloon injury in the rat
    • Zahger D, Fishbein MC, Garfinkel LI, Shah PK, Forrester JS, Regnstrom J, Yano J, Cercek B. VCL, an antagonist of the platelet GPIb receptor, markedly inhibits platelet adhesion and intimal thickening after balloon injury in the rat. Circulation 1995; 92: 1269-73.
    • (1995) Circulation , vol.92 , pp. 1269-1273
    • Zahger, D.1    Fishbein, M.C.2    Garfinkel, L.I.3    Shah, P.K.4    Forrester, J.S.5    Regnstrom, J.6    Yano, J.7    Cercek, B.8
  • 33
    • 0025143892 scopus 로고
    • Comparative effects of aspirin, a synthetic thrombin inhibitor and a monoclonal antiplatelet glycoprotein IIb/IIIa antibody on coronary artery reperfusion, reocclusion and bleeding with recombinant tissue-type plasminogen activator in a canine preparation
    • Yasuda T, Gold HK, Yaoita H, Leinbach RC, Guerrero JL, Jang IK, Holt R, Fallon JT, Collen D. Comparative effects of aspirin, a synthetic thrombin inhibitor and a monoclonal antiplatelet glycoprotein IIb/IIIa antibody on coronary artery reperfusion, reocclusion and bleeding with recombinant tissue-type plasminogen activator in a canine preparation. J Am Coll Cardiol 1990; 16: 714-22.
    • (1990) J Am Coll Cardiol , vol.16 , pp. 714-722
    • Yasuda, T.1    Gold, H.K.2    Yaoita, H.3    Leinbach, R.C.4    Guerrero, J.L.5    Jang, I.K.6    Holt, R.7    Fallon, J.T.8    Collen, D.9
  • 36
    • 0028001673 scopus 로고
    • Intracranial bleeding, fibrinolysis, and anticoagulation. Causal connections and clinical implications
    • Sobel BE. Intracranial bleeding, fibrinolysis, and anticoagulation. Causal connections and clinical implications. Circulation 1994; 90: 2147-51.
    • (1994) Circulation , vol.90 , pp. 2147-2151
    • Sobel, B.E.1


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