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Volumn 11, Issue 2, 1998, Pages 133-138

New polymerase chain reaction-based diagnostic techniques for bacterial respiratory infection

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC SENSITIVITY; BORDETELLA PERTUSSIS; CHLAMYDOPHILA PNEUMONIAE; DISEASE SEVERITY; HUMAN; MYCOBACTERIUM TUBERCULOSIS; POLYMERASE CHAIN REACTION; RESPIRATORY TRACT INFECTION; REVIEW; STREPTOCOCCUS PNEUMONIAE;

EID: 0031957611     PISSN: 09517375     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001432-199804000-00008     Document Type: Review
Times cited : (4)

References (51)
  • 1
    • 0027524771 scopus 로고
    • Evaluation of polymerase chain reaction for diagnosis of pneumococcal pneumonia
    • Rudolph KM, Parkinson AJ, Black CM, Mayer LW. Evaluation of polymerase chain reaction for diagnosis of pneumococcal pneumonia. J Clin Microb 1993; 31:2661-2666.
    • (1993) J Clin Microb , vol.31 , pp. 2661-2666
    • Rudolph, K.M.1    Parkinson, A.J.2    Black, C.M.3    Mayer, L.W.4
  • 2
    • 0027961021 scopus 로고
    • Comparison of PCR assay with bacterial culture for detecting Streptococcus pneumoniae in middle ear fluid of children with acute otitis media
    • Virolainen A, Salo P, Jero J, Karma P, Eskola J, Leinonen M. Comparison of PCR assay with bacterial culture for detecting Streptococcus pneumoniae in middle ear fluid of children with acute otitis media. J Clin Microbiol 1994; 32:2667-2670.
    • (1994) J Clin Microbiol , vol.32 , pp. 2667-2670
    • Virolainen, A.1    Salo, P.2    Jero, J.3    Karma, P.4    Eskola, J.5    Leinonen, M.6
  • 3
    • 0028873515 scopus 로고
    • Diagnosis of bacteraemic pneumococcal pneumonia by amplification of pneumolysin gene fragment in serum
    • Salo P, Ortqvist A, Leinonen M. Diagnosis of bacteraemic pneumococcal pneumonia by amplification of pneumolysin gene fragment in serum. J Infect Dis 1995; 171:479-482.
    • (1995) J Infect Dis , vol.171 , pp. 479-482
    • Salo, P.1    Ortqvist, A.2    Leinonen, M.3
  • 4
    • 0028209946 scopus 로고
    • Detection of Streptococcus pneumoniae in sputum samples by PCR
    • Gillespie SH, Ullman C, Smith MD, Emery V. Detection of Streptococcus pneumoniae in sputum samples by PCR. J Clin Microbiol 1994; 32:1308-1311.
    • (1994) J Clin Microbiol , vol.32 , pp. 1308-1311
    • Gillespie, S.H.1    Ullman, C.2    Smith, M.D.3    Emery, V.4
  • 6
    • 0028020625 scopus 로고
    • Detection of bacterial DNA in cerebrospinal fluid by an assay for simultaneous detection of Neisseria meningitidis, Heamophilus influenzae, and streptococci using a semi-nested PCR strategy
    • Radstrom P, Backman A, Qian N, Kragsbjerg P, Pahlson C, Olcen P. Detection of bacterial DNA in cerebrospinal fluid by an assay for simultaneous detection of Neisseria meningitidis, Heamophilus influenzae, and streptococci using a semi-nested PCR strategy. J Clin Microbiol 1994; 32:2738-2744.
    • (1994) J Clin Microbiol , vol.32 , pp. 2738-2744
    • Radstrom, P.1    Backman, A.2    Qian, N.3    Kragsbjerg, P.4    Pahlson, C.5    Olcen, P.6
  • 7
    • 0030023805 scopus 로고    scopus 로고
    • Combinational detection of autolysin and penicillin-binding protein 2b genes of Streptococcus pneumoniae by PCR
    • Ubukata K, Asahi Y, Yamane A, Konno M. Combinational detection of autolysin and penicillin-binding protein 2b genes of Streptococcus pneumoniae by PCR. J Clin Microbiol 1996; 34:592-596. The diagnosis of penicillin resistance in S. pneumoniae was achieved using a combination of PCRs directed against sensitive and resistant penicillin-binding protein genes. In addition, an autolysin-specific PCR was used in parallel to indicate that strains were S. pneumoniae.
    • (1996) J Clin Microbiol , vol.34 , pp. 592-596
    • Ubukata, K.1    Asahi, Y.2    Yamane, A.3    Konno, M.4
  • 8
    • 0028092010 scopus 로고
    • Origin and molecular epidemiology of penicillin binding protein mediated resistance to β-lactam antibiotics
    • Dowson CG, Coffey TJ, Spratt BG. Origin and molecular epidemiology of penicillin binding protein mediated resistance to β-lactam antibiotics. Trends Microbiol 1994; 2:361-365.
    • (1994) Trends Microbiol , vol.2 , pp. 361-365
    • Dowson, C.G.1    Coffey, T.J.2    Spratt, B.G.3
  • 9
    • 29344465367 scopus 로고    scopus 로고
    • Determination of penicillin susceptibility of Streptococcus pneumoniae using the polymerase chain reaction
    • Jalal H, Organji S, Reynolds J, Bennett D, Omason E, Millar MR. Determination of penicillin susceptibility of Streptococcus pneumoniae using the polymerase chain reaction. J Clin Pathol Mol Pathol 1997; 50:45-50. The authors used a combination of PCR reactions directed against sensitive and resistant penicillin-binding protein genes. They were able to detect susceptible strains easily, but many isolates that are resistant were not correctly identified as resistant. This is because the resistant PCR reaction can is only positive if the unknown isolates share seguence homology with these primers. Resistant isolates are highly heterogeneous and it is inevitable that many resistant strains will not be detected by this approach.
    • (1997) J Clin Pathol Mol Pathol , vol.50 , pp. 45-50
    • Jalal, H.1    Organji, S.2    Reynolds, J.3    Bennett, D.4    Omason, E.5    Millar, M.R.6
  • 10
    • 0030692851 scopus 로고    scopus 로고
    • An outbreak of penicillin-resistant Streptococcus pneumoniae (PRSP) investigated by a PCR-based genotyping method
    • Gillespie SH, McHugh TD, Hughes JE, Dickens A, Kyi MS, Kelsey M. An outbreak of penicillin-resistant Streptococcus pneumoniae (PRSP) investigated by a PCR-based genotyping method. J Clin Pathol 1997; 50:847-851. Penicillin-binding protein genes were amplified by PCR and then subjected to endonuclease digestion. Sensitive patterns could be distinguished from resistant patterns and the RFLPs were used to follow the spread of a serotype 9 resistant strain that was causing a hospital outbreak.
    • (1997) J Clin Pathol , vol.50 , pp. 847-851
    • Gillespie, S.H.1    McHugh, T.D.2    Hughes, J.E.3    Dickens, A.4    Kyi, M.S.5    Kelsey, M.6
  • 11
    • 0028089279 scopus 로고
    • The role of polymerase chain reaction in the diagnosis of mycobacterial infections
    • Hawkey PM. The role of polymerase chain reaction in the diagnosis of mycobacterial infections. Rev Med Microbiol 1994; 5:21-32.
    • (1994) Rev Med Microbiol , vol.5 , pp. 21-32
    • Hawkey, P.M.1
  • 12
    • 33746408222 scopus 로고
    • The application of molecular techniques to the diagnosis and epidemiology of mycobacterial diseases
    • Butcher PD, Hutchinson NA, Doran TJ, Banerjee DK. The application of molecular techniques to the diagnosis and epidemiology of mycobacterial diseases. J Appl Bacteriol 1995; 81 (suppl):53-71.
    • (1995) J Appl Bacteriol , vol.81 , Issue.SUPPL. , pp. 53-71
    • Butcher, P.D.1    Hutchinson, N.A.2    Doran, T.J.3    Banerjee, D.K.4
  • 13
    • 0030982165 scopus 로고    scopus 로고
    • IS6110 homologs are present in multiple copies in mycobacteria other than tuberculosis
    • McHugh TD, Newport LE, Gillespie SH. IS6110 homologs are present in multiple copies in mycobacteria other than tuberculosis. J Clin Microbiol 1997; 35:1769-1771. This is an extension of a previous observation that a portion of the IS611O insertion sequence shares homology with DNA from non-tuberculosis species. As this insertion sequence is commonly used as a target for diagnostic PCR reactions such homology may result in false positive results. In this study, the authors identified that the homologous DNA was present in multiple copies in the genomic DNA of non-tuberculosis mycobacteria. This indicated that mycobactena may possess a family of IS3 insertion sequences.
    • (1997) J Clin Microbiol , vol.35 , pp. 1769-1771
    • McHugh, T.D.1    Newport, L.E.2    Gillespie, S.H.3
  • 14
    • 0029102666 scopus 로고
    • Routine application of the polymerase chain reaction for detection of Mycobacterium tuberculosis in clinical samples
    • Noordhoek GT, Kaan JA, Mulder S, Wilke H, Kolk AHJ. Routine application of the polymerase chain reaction for detection of Mycobacterium tuberculosis in clinical samples. J Clin Pathol 1995; 48:810-814 .
    • (1995) J Clin Pathol , vol.48 , pp. 810-814
    • Noordhoek, G.T.1    Kaan, J.A.2    Mulder, S.3    Wilke, H.4    Kolk, A.H.J.5
  • 15
    • 19244364157 scopus 로고    scopus 로고
    • Comparison of the amplified Mycobacterium tuberculosis (MTB) direct test, Amplicor MTB PCR and IS6110-PCR for detection of MTB in respiratory specimens
    • Dalovisio JR, Montenegro-James S, Kemmerly SA , Genre CF, Chambers R, Greer D, et al. Comparison of the amplified Mycobacterium tuberculosis (MTB) direct test, Amplicor MTB PCR and IS6110-PCR for detection of MTB in respiratory specimens. Clin Infect Dis 1996; 23:1099-2106.
    • (1996) Clin Infect Dis , vol.23 , pp. 1099-2106
    • Dalovisio, J.R.1    Montenegro-James, S.2    Kemmerly, S.A.3    Genre, C.F.4    Chambers, R.5    Greer, D.6
  • 16
    • 0030978299 scopus 로고    scopus 로고
    • Comparison of two a utomated DNA amplification systems with a manual one-tuber nested PCR assay for the diagnosis of pulmonary tuberculosis
    • Yuen K-Y, Yam C, Wong L-P, Seto W-H. Comparison of two a utomated DNA amplification systems with a manual one-tuber nested PCR assay for the diagnosis of pulmonary tuberculosis. J Clin Microbiol 1997; 35:1385-1389. A clinical evaluation of the Roche Amplicor, Abbot LCx systems and an in-house nested PCR.
    • (1997) J Clin Microbiol , vol.35 , pp. 1385-1389
    • Yuen, K.-Y.1    Yam, C.2    Wong, L.-P.3    Seto, W.-H.4
  • 17
    • 0029024564 scopus 로고
    • Rapid identification of mycobacteria from AIDS patients by capillary electrophoretic profiling of amplified SOD gene
    • Bull TJ, Shanson DC, Archard LC. Rapid identification of mycobacteria from AIDS patients by capillary electrophoretic profiling of amplified SOD gene. J Clin Pathol 1995; 48:M124-M132.
    • (1995) J Clin Pathol , vol.48
    • Bull, T.J.1    Shanson, D.C.2    Archard, L.C.3
  • 20
    • 0029928296 scopus 로고    scopus 로고
    • Comparison of polymerase chain reaction for IS6110 and amplicor in the diagnosis of tuberculosis
    • Dilworth JP, Goyal M, Young DB, Shaw RJ. Comparison of polymerase chain reaction for IS6110 and amplicor in the diagnosis of tuberculosis. Thorax 1996; 51:320-322.
    • (1996) Thorax , vol.51 , pp. 320-322
    • Dilworth, J.P.1    Goyal, M.2    Young, D.B.3    Shaw, R.J.4
  • 21
    • 0028342826 scopus 로고
    • Rapid diagnosis of tuberculous meningitis by a simplified nested amplification protocol
    • Liu PY, Shi ZY, Lau YJ, Hu BS. Rapid diagnosis of tuberculous meningitis by a simplified nested amplification protocol. Neurology 1994; 44:1161-1164.
    • (1994) Neurology , vol.44 , pp. 1161-1164
    • Liu, P.Y.1    Shi, Z.Y.2    Lau, Y.J.3    Hu, B.S.4
  • 22
    • 0026552837 scopus 로고
    • Detection of mucobacterial DNA in pleural fluid from patients with tuberculosis pleurisy by means of the polymerase chain reaction: Comparison of two protocols
    • De Lassence A, Lecossier D, Pierre C, Cadranel J, Stern M, Hance AJ. Detection of mucobacterial DNA in pleural fluid from patients with tuberculosis pleurisy by means of the polymerase chain reaction: comparison of two protocols. Thorax 1992; 47:265-269.
    • (1992) Thorax , vol.47 , pp. 265-269
    • De Lassence, A.1    Lecossier, D.2    Pierre, C.3    Cadranel, J.4    Stern, M.5    Hance, A.J.6
  • 23
    • 0028217204 scopus 로고
    • The detection of Mycobacterium tuberculosis in bone marrow aspirate using the polymerase chain reaction
    • Lombard EH, Victor T, Jordaan A, van Helden PD. The detection of Mycobacterium tuberculosis in bone marrow aspirate using the polymerase chain reaction. Tubercle Lung Dis 1994; 75:65-69.
    • (1994) Tubercle Lung Dis , vol.75 , pp. 65-69
    • Lombard, E.H.1    Victor, T.2    Jordaan, A.3    Van Helden, P.D.4
  • 25
    • 0027538104 scopus 로고
    • Detection of rifampicin resistance mutations in Mycobacterium tuberculosis
    • Telenti A, Imboden P, Marchesi F, Lowrie D, Cole S, Colston J, et al. Detection of rifampicin resistance mutations in Mycobacterium tuberculosis. Lancet 1993; 341:647-650.
    • (1993) Lancet , vol.341 , pp. 647-650
    • Telenti, A.1    Imboden, P.2    Marchesi, F.3    Lowrie, D.4    Cole, S.5    Colston, J.6
  • 26
    • 0028839319 scopus 로고
    • Antimicrobial agent resistance in mycobacteria: Molecular genetic insights
    • Musser JM. Antimicrobial agent resistance in mycobacteria: molecular genetic insights. Clin Microbiol Rev 1995; 8:496-514.
    • (1995) Clin Microbiol Rev , vol.8 , pp. 496-514
    • Musser, J.M.1
  • 27
    • 0031057723 scopus 로고    scopus 로고
    • Genotypic assessment of isoniazid and rifampicin resistance in Mycobacterium tuberculosis: A blind study at reference laboratory level
    • Telenti A, Honore N, Bernasconi C, March J, Ortega A, Heym B, et al. Genotypic assessment of isoniazid and rifampicin resistance in Mycobacterium tuberculosis: a blind study at reference laboratory level. J Clin Microbiol 1997; 35:719-723.
    • (1997) J Clin Microbiol , vol.35 , pp. 719-723
    • Telenti, A.1    Honore, N.2    Bernasconi, C.3    March, J.4    Ortega, A.5    Heym, B.6
  • 28
    • 0031003128 scopus 로고    scopus 로고
    • Evaluation of a line-probe assay kit for characterization of rpoB mutation in rifampicm resistant Mycobacterium tuberculosis isolates from New York City
    • Cooksey RC, Morlock GP, Glickman S, Crawford JT. Evaluation of a line-probe assay kit for characterization of rpoB mutation in rifampicm resistant Mycobacterium tuberculosis isolates from New York City. J Clin Micrbiol 1997; 35:1281-1283. This study used the commercial line probe assay to investigate susceptibility to rifampicin rapidly. It was successful in detecting resistance in almost all of the collection of rifamicin-resistant isolates tested.
    • (1997) J Clin Micrbiol , vol.35 , pp. 1281-1283
    • Cooksey, R.C.1    Morlock, G.P.2    Glickman, S.3    Crawford, J.T.4
  • 29
    • 0030893650 scopus 로고    scopus 로고
    • Detection of resistance to isoniazid, rifampicin, and streptomycin in clinical isolates of Mycobacterium tuberculosis by molecular methods
    • Nachamkin I, Kang C, Weinstein MP. Detection of resistance to isoniazid, rifampicin, and streptomycin in clinical isolates of Mycobacterium tuberculosis by molecular methods. Clin Infect Dis 1997; 24:894-900. The authors used RFLP, heteroduplex and direct sequencing to evaluate the molecular basis of resistance in isolates of M. tuberculosis. Known resistance mutations could be detected rapidly for streptomycin, rifampicin and isolniazid. A proportion of resistant strains were not identified by molecular techniques.
    • (1997) Clin Infect Dis , vol.24 , pp. 894-900
    • Nachamkin, I.1    Kang, C.2    Weinstein, M.P.3
  • 30
    • 0031053260 scopus 로고    scopus 로고
    • Monitoring the therapy of pulmonary tuberculosis by nested polymerase chain reaction assay
    • Yuen KY, Chan KS, Chan CM, Ho PL, Ng MH. Monitoring the therapy of pulmonary tuberculosis by nested polymerase chain reaction assay. J Infect 1997; 34:29-33. An IS6110 PCR was used on sequential specimens from patients with pulmonary tuberculosis. Patients who subsequently relapsed were more likely to remain PCR-positive after 6 months of treatment. This was a useful study, but care must be taken that the results are not generalized inappropriately. Only sequential PCR assays can give an indication of the response to treatment, the significance of a single positive or negative sample cannot be interpreted during the course of a patient's therapy.
    • (1997) J Infect , vol.34 , pp. 29-33
    • Yuen, K.Y.1    Chan, K.S.2    Chan, C.M.3    Ho, P.L.4    Ng, M.H.5
  • 31
    • 0028360788 scopus 로고
    • Diagnosis of Mycoplasma pneumoniae infection with community acquired pneumonia by polymerase reaction enzyme immunoassay
    • Gaydos CA, Eiden JJ, Oldach D, Munidy LM, Auwaeter P, Warner ML, et al. Diagnosis of Mycoplasma pneumoniae infection with community acquired pneumonia by polymerase reaction enzyme immunoassay. Clin Infect Dis 1994; 19:157-160.
    • (1994) Clin Infect Dis , vol.19 , pp. 157-160
    • Gaydos, C.A.1    Eiden, J.J.2    Oldach, D.3    Munidy, L.M.4    Auwaeter, P.5    Warner, M.L.6
  • 32
    • 0027321448 scopus 로고
    • Detection of Mycoplasma pneumoniae and Mycoplasma genitalium in clinical samples by polymerase chain reaction
    • De Barbeyrac B, Bernet-Poggi C, Febrer F, Renaudin H, Dupon M, Bébéar C. Detection of Mycoplasma pneumoniae and Mycoplasma genitalium in clinical samples by polymerase chain reaction. Clin Infect Dis 1993; 17:S83-S89.
    • (1993) Clin Infect Dis , vol.17
    • De Barbeyrac, B.1    Bernet-Poggi, C.2    Febrer, F.3    Renaudin, H.4    Dupon, M.5    Bébéar, C.6
  • 33
    • 0029818143 scopus 로고    scopus 로고
    • Detection of Mycoplasma pneumoniae by two polymerase chain reactions and role of M. pneumoniae in acute respiratory tract infections in pediatric patients
    • leven M, Ursi H, van Bever H, Quint W, Neisters HGM, Goosens H. Detection of Mycoplasma pneumoniae by two polymerase chain reactions and role of M. pneumoniae in acute respiratory tract infections in pediatric patients. J Infect Dis 1996; 173:1445-1452.
    • (1996) J Infect Dis , vol.173 , pp. 1445-1452
    • Leven, M.1    Ursi, H.2    Van Bever, H.3    Quint, W.4    Hgm, N.5    Goosens, H.6
  • 34
    • 0029395958 scopus 로고
    • Diagnosis of Mycoplasma pneumoniae pneumonia in pediatrie patients by polymerase chain reaction
    • Buck GE, Eid NS. Diagnosis of Mycoplasma pneumoniae pneumonia in pediatrie patients by polymerase chain reaction. Pediatr Pulmonol 1995: 20:297-300.
    • (1995) Pediatr Pulmonol , vol.20 , pp. 297-300
    • Buck, G.E.1    Eid, N.S.2
  • 35
    • 0028843413 scopus 로고
    • Comparison of nasopharyngeal aspirates and throat swab specimens in a polymerase chain reaction based test for Mycoplasma pneumoniae
    • Renzikov M, Blackmore TK, Finlay-Jones JJ, Gorden DL. Comparison of nasopharyngeal aspirates and throat swab specimens in a polymerase chain reaction based test for Mycoplasma pneumoniae. Eur J Clin Microbiol Infect Dis 1995; 14:58-61.
    • (1995) Eur J Clin Microbiol Infect Dis , vol.14 , pp. 58-61
    • Renzikov, M.1    Blackmore, T.K.2    Finlay-Jones, J.J.3    Gorden, D.L.4
  • 36
    • 0027423293 scopus 로고
    • Rapid detection of Legionella species in bronchoalveolar lavage fluids with the EnviroAmp Legionella PCR amplification and detection kit
    • Kessler HH, Rheinthaler FF, Pschaid A. Piere K, KleinHappl B, Eber E, Marth E. Rapid detection of Legionella species in bronchoalveolar lavage fluids with the EnviroAmp Legionella PCR amplification and detection kit. J Clin Microbiol 1993; 31:3325-3328.
    • (1993) J Clin Microbiol , vol.31 , pp. 3325-3328
    • Kessler, H.H.1    Rheinthaler, F.F.2    Pschaid, A.3    Piere, K.4    Kleinhappl, B.5    Eber, E.6    Marth, E.7
  • 38
    • 0028263393 scopus 로고
    • Comparison of conventional culture and PCR for the detection of Legionella in hospital water supplies
    • Maiwald M, Kissel K, Srimnang S, von Knebel-Doebenitz M, Sonntag HG. Comparison of conventional culture and PCR for the detection of Legionella in hospital water supplies. J Appl Bacteriol 1994; 76:216-225.
    • (1994) J Appl Bacteriol , vol.76 , pp. 216-225
    • Maiwald, M.1    Kissel, K.2    Srimnang, S.3    Von Knebel-Doebenitz, M.4    Sonntag, H.G.5
  • 41
    • 0028288878 scopus 로고
    • Diagnostic utility of PCR, enzyme immunoassay. culture and serology for detection of Chlamydia pneumoniae in symptomatic and asymptomatic patients
    • Gaydos CA, Roblin PM, Hammerschlag MR, Hyman CL, Eiden JJ. Schacter J, Quinn TC. Diagnostic utility of PCR, enzyme immunoassay. culture and serology for detection of Chlamydia pneumoniae in symptomatic and asymptomatic patients. J Clin Microbiol 1994; 32:903-905.
    • (1994) J Clin Microbiol , vol.32 , pp. 903-905
    • Gaydos, C.A.1    Roblin, P.M.2    Hammerschlag, M.R.3    Hyman, C.L.4    Eiden, J.J.5    Schacter, J.6    Quinn, T.C.7
  • 42
    • 0030960414 scopus 로고    scopus 로고
    • Rapid diagnosis of respiratory Clamydia pneumoniae infection by nested touchdown polymerase chain reaction compared with culture and antigen detection EIA
    • Boman J, Allard A, Persson K, Lundborg M, Juto P, Wadell G. Rapid diagnosis of respiratory Clamydia pneumoniae infection by nested touchdown polymerase chain reaction compared with culture and antigen detection EIA. J Infect Dis 1997; 175:1523-1526. A nested PCR protocol was used to detect C. pneumoniae in sputum from patients with community-acquired pneumonia in Sweden. The PCR proved almost as sensitive as serological methods in making a diagnosis. This represents an improved diagnostic yield, and may allow further epidemiological investigations to establish the role of this pathogen in community-acquired pneumonia.
    • (1997) J Infect Dis , vol.175 , pp. 1523-1526
    • Boman, J.1    Allard, A.2    Persson, K.3    Lundborg, M.4    Juto, P.5    Wadell, G.6
  • 43
    • 0029757423 scopus 로고    scopus 로고
    • Clinical characteristics and diagnostic value of polymerase chain reaction detection in BAL
    • Dalhof K, Maass M. Clinical characteristics and diagnostic value of polymerase chain reaction detection in BAL. Chest 1996; 110:351-356. PCR targeted on the HL1/HLR primer pair was used to investigate lavage fluid prospectively. The population included a number of HIV-seropositive individuals. C. pneumoniae was found as a single pathogen in many hospital patients. This included the HIV-infected individuals who would otherwise have been difficult to diagnose by conventional serological methods.
    • (1996) Chest , vol.110 , pp. 351-356
    • Dalhof, K.1    Maass, M.2
  • 44
    • 0027223231 scopus 로고
    • Detection of Chlamydia pneumoniae and Chlamydia psittaci in sputum samples by PCR
    • Tong CY, Sillis M. Detection of Chlamydia pneumoniae and Chlamydia psittaci in sputum samples by PCR. J Clin Pathol 1993; 46:313-317.
    • (1993) J Clin Pathol , vol.46 , pp. 313-317
    • Tong, C.Y.1    Sillis, M.2
  • 46
    • 0030611310 scopus 로고    scopus 로고
    • Comparison of nasopharyngeal and throat swabs for the detection of Chlamydia pneumoniae and Mycoplasma pneumoniae by polymerase chain reaction
    • Gnarpe J, Lundback A, Gnarpe H, Sundelof B. Comparison of nasopharyngeal and throat swabs for the detection of Chlamydia pneumoniae and Mycoplasma pneumoniae by polymerase chain reaction. Scand J Infect Dis 1997; 104:11-12.
    • (1997) Scand J Infect Dis , vol.104 , pp. 11-12
    • Gnarpe, J.1    Lundback, A.2    Gnarpe, H.3    Sundelof, B.4
  • 47
    • 0028912506 scopus 로고
    • Polymerase chain reaction identification of Bordetella pertussis infections in vaccinees and family members in a pertussis vaccine efficacy trial in Germany
    • Schläpfer G, Cherry U, Heininger M, Uberall S, Schmitt-Grohé S, Laussucq S, Just M, Stehr K. Polymerase chain reaction identification of Bordetella pertussis infections in vaccinees and family members in a pertussis vaccine efficacy trial in Germany. Pediatr Infect Dis 1995; 14:209-214.
    • (1995) Pediatr Infect Dis , vol.14 , pp. 209-214
    • Schläpfer, G.1    Cherry, U.2    Heininger, M.3    Uberall, S.4    Schmitt-Grohé, S.5    Laussucq, S.6    Just, M.7    Stehr, K.8
  • 48
    • 0028205609 scopus 로고
    • Sensitive and specific polymerase chain reaction assays for detection of Bordetella pertussis in nasopharyngeal samples
    • He Q, Mertsola J, Soiini H, Viljanen MK. Sensitive and specific polymerase chain reaction assays for detection of Bordetella pertussis in nasopharyngeal samples. J Pediatr 1994; 124:421-426.
    • (1994) J Pediatr , vol.124 , pp. 421-426
    • He, Q.1    Mertsola, J.2    Soiini, H.3    Viljanen, M.K.4
  • 50
    • 0027533351 scopus 로고
    • Identification of Bordetella pertussis in nasopharyngeal swabs by PCR amplification of a region of the adenyl cyclase gene
    • Douglas E, Coote JG, Parton R, McPheat W. Identification of Bordetella pertussis in nasopharyngeal swabs by PCR amplification of a region of the adenyl cyclase gene. J Med Microbiol 1993; 38:140-144.
    • (1993) J Med Microbiol , vol.38 , pp. 140-144
    • Douglas, E.1    Coote, J.G.2    Parton, R.3    McPheat, W.4


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