Chemopreventive effects of NSAIDS against colorectal cancer: Regulation of apoptosis and mitosis by COX-1 and COX-2

Histology and Histopathology

Volumn 13, Issue 2, 1998, Pages 591-597

  Watson, A J M ^a  

^a HOPE HOSPITAL   (United Kingdom)

Author keywords

Apoptosis; Colorectal neoplasia; Cyclooxygenase enzymes; Intestine

Indexed keywords

NONSTEROID ANTIINFLAMMATORY AGENT;

APOPTOSIS; ARACHIDONIC ACID METABOLISM; CANCER PREVENTION; COLORECTAL CANCER; DRUG EFFECT; HUMAN; MITOSIS; REVIEW;

EID: 0031957419     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (3)

1. Baker S.J., Peisinger A.C., Jessup J.M., Paraskeva C., Markowitz S., Willson J.K.V., Hamilton S. and Vogelstein B. (1990). p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res. 50, 7717-7722.
2. Barnard J.A., Beauchamp R.D., Coffey R.J. and Moses H.L. (1989). Regulation of intestinal epithelial cell growth by transforming factor type beta. Proc. Natl. Acad. Sci. USA 86, 1578-82.
3. Basu A.K. and Marnett L.J. (1983). Unequivocal demonstration that malonidialdehyde is a mutagen. Carcingenesis 3, 331-333.