Hypoxemic resuscitation in newborn piglets: Recovery of somatosensory evoked potentials, hypoxanthine, and acid-base balance

Pediatric Research

Volumn 43, Issue 5, 1998, Pages 690-696

  Feet, Björn Aage ^a,b   Medbö, Sverre ^a,b   Rootwelt, Terje ^a   Ganes, Trond ^a   Saugstad, Ola D ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ACID; BASE; HYPOXANTHINE; OXYGEN;

ACID BASE BALANCE; ALKALOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL CARBON DIOXIDE TENSION; ARTERIAL OXYGEN TENSION; ARTICLE; CONTROLLED STUDY; EVOKED SOMATOSENSORY RESPONSE; NEWBORN; NEWBORN HYPOXIA; NONHUMAN; OXYGEN THERAPY; PRIORITY JOURNAL; RESUSCITATION; SWINE;

EID: 0031957120     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199805000-00019     Document Type: Article

References (45)

1. Saugstad OD 1990 Oxygen toxicity in the neonatal period. Acta Paediatr Scand 79:881-892
2. Saugstad OD 1996 Resuscitation of newborn infants: do we need new guidelines? Prenatal Neonatal Med 1:1-3
3. Rootwelt T, Loberg EM, Moen A, Oyasaeter S, Saugstad OD 1992 Hypoxemia and reoxygenation with 21% or 100% oxygen in newborn pigs: changes in blood pressure, base deficit, and hypoxanthine and brain morphology. Pediatr Res 32:107-113
4. 2 in newborn pigs. J Appl Physiol 75:2054-2060
5. Zwemer CF, Whitesall SE, D'Alecy LG 1994 Cardiopulmonary-cerebral resuscitation with 100% oxygen exacerbates neurological dysfunction following nine minutes of normothermic cardiac arrest in dogs. Resuscitation 27:159-170
6. (+)-ATPase activity in striatum of newborn piglets. Brain Res 696:161-164
7. 2 in newborn piglets: extracellular hypoxanthine in cerebral cortex and femoral muscle. Crit Care Med 25:1384-1391
8. Ramji S, Ahuja S, Thirupuram S, Rootwelt T, Rooth G, Saugstad OD 1993 Resuscitation of asphyxie newborn infants with room air or 100% oxygen. Pediatr Res 34:809-812
9. Fercakova A, Marsala M, Marsala J 1994 Influence of graded postischemic reoxgenation on reperfusion alterations in rabbit dorsal root ganglion neurons. J Hirnforsch 35:295-302
10. Orendacova J, Marsala M, Marsala J 1991 The blood-brain barrier permeability in graded postischemic spinal cord reoxygenation in rabbits. Neurosci Lett 128:143-146
11. Fridovich I 1970 Quantitative aspects of the production of superoxide anion radical by milk xanthine oxidase. J Biol Chem 245:4053-4057
12. Saugstad OD, Aasen AO 1980 Plasma hypoxanthine concentrations in pigs. A prognostic aid in hypoxia. Eur Surg Res 12:123-129
13. Siesjo BK 1992 Pathophysiology and treatment of focal cerebral ischemia. II. Mechanisms of damage and treatment. J Neurosurg 77:337-354
14. Vannucci RC 1990 Experimental biology of cerebral hypoxia-ischemia: relation to perinatal brain damage. Pediatr Res 27:317-26
15. Saugstad OD 1975 Hypoxanthine as a measurement of hypoxia. Pediatr Res 9:158-161
16. Saugstad OD 1988 Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production. Pediatr Res 23:143-150
17. Simmonds RJ, Coade SB, Harkness RA, Drury L, Hytten FE 1982 Nucleotide, nucleoside and purine base concentrations in human placentae. Placenta 3:29-38
18. Craner SL, Ray RH 1991 Somatosensory cortex of the neonatal pig. I. Topographic organization of the primary somatosensory cortex. J Comp Neurol 306:24-38
19. Simmonds RJ, Harkness RA 1981 High-performance liquid chromatographic methods for base and nucleoside analysis in extracellular fluids and in cells. J Chromatogr 226:369-381
20. Poulsen JP, Oyasaeter S, Saugstad OD 1993 Hypoxanthine, xanthine, and uric acid in newborn pigs during hypoxemia followed by resuscitation with room air or 100% oxygen. Crit Care Med 21:1058-1065
21. Rooth G, Engleson G, Törnblom M 1966 A follow-up study of premature infants treated with low oxygen tension. Acta Paediatr Scand 55:85-87
22. Engleson G, Rooth G, Sjöstedt S 1958 Treatment of premature infants with 15% oxygen. Acta Paediatr Scand Suppl 118:47-49
23. Mortola JP, Frappell PB, Frappell DE, Villena-Cabrera N, Villena-Cabrera M, Pena F 1992 Ventilation and gaseous metabolism in infants born at high altitude, and their responses to hyperoxia. Am Rev Respir Dis 146:1206-1209
24. Fandrey J 1995 Hypoxia-inducible gene expression. Respir Physiol 101:1-10
25. Guillemin K, Krasnow MA 1997 The hypoxic response: huffing and HIFing. Cell 89:9-12
26. Perry MA, Wadhwa SS 1988 Gradual reintroduction of oxygen reduces reperfusion injury in cat stomach. Am J Physiol 254:G366-G372
27. Clark ET, Gewertz BL 1992 Limiting oxygen delivery attenuates intestinal reperfusion injury. J Surg Res 53:485-489
28. Vannucci RC, Towfighi J, Heitjan DF, Brucklacher RM 1995 Carbon dioxide protects the perinatal brain from hypoxic-ischemic damage: an experimental study in the immature rat. Pediatrics 95:868-874
29. Ropper AH 1986 Evoked potentials in cerebral ischemia. Stroke 17:3-5
30. Hurn PD, Koehler RC, Norris SE, Blizzard KK, Traystman RJ 1991 Dependence of cerebral energy phosphate and evoked potential recovery on end-ischemic pH. Am J Physiol 260:H532-H541
31. McPherson RW, Zeger S, Traystman RJ 1986 Relationship of somatosensory evoked potentials and cerebral oxygen consumption during hypoxic hypoxia in dogs. Stroke 17:30-36
32. Nishijima MK, Koehler RC, Hurn PD, Eleff SM, Norris S, Jacobus WE, Traystman RJ 1989 Postischemic recovery rate of cerebral ATP, phosphocreatine, pH, and evoked potentials. Am J Physiol 257:H1860-H1870
33. Willis J, Duncan C, Bell R 1987 Short-latency somatosensory evoked potentials in perinatal asphyxia. Pediatr Neurol 3:203-207
34. Majnemer A, Rosenblatt B, Riley PS 1990 Prognostic significance of multimodality evoked response testing in high-risk newborns. Pediatr Neurol 6:367-374
35. Lorek A, Takei Y, Cady EB, Wyatt JS, Penrice J, Edwards AD, Peebles D, Wylezinska M, Owen-Reece H, Kirkbride V, Cooper CE, Aldridge RF, Roth SC, Brown G, Delphy DT, Reynolds EOR 1994 Delayed ("secondary") cerebral energy failure after acute hypoxia-ischemia in the newborn piglet: continuous 48-hour studies by phosphorus magnetic resonance spectroscopy. Pediatr Res 36:699-706
36. Hope PL, Costello AM, Cady EB, Delpy DT, Tofts PS, Chu A, Hamilton PA, Reynolds EO, Wilkie DR 1984 Cerebral energy metabolism studied with phosphorus NMR spectroscopy in normal and birth-asphyxiated infants. Lancet 2:366-370
37. Roth SC, Edwards AD, Cady EB, Delpy DT, Wyatt JS, Azzopardi D, Baudin J, Townsend J, Stewart AL, Reynolds EO 1992 Relation between cerebral oxidative metabolism following birth asphyxia, and neurodevelopmental outcome and brain growth at one year. Dev Med Child Neurol 34:285-295
38. LeBlanc MH, Huang M, Vig V, Patel D, Smith EE 1993 Glucose affects the severity of hypoxic-ischemic brain injury in newborn pigs. Stroke 24:1055-1062
39. LeBlanc MH, Huang M, Patel D, Smith EE, Devidas M 1994 Glucose given after hypoxic ischemia does not affect brain injury in piglets. Stroke 25:1443-1447
40. Akeson J, Nilsson F, Ryding E, Messeter K 1992 A porcine model for sequential assessments of cerebral haemodynamics and metabolism. Acta Anaesthesiol Scand 36:419-426
41. Shapiro HM 1986 Anesthesia effects upon cerebral blood flow, cerebral metabolism, electroencephalogram, and evoked potentials. In: Miller RD (ed) Anesthesia. Churchill-Livingstone, New York, pp 1249-1288
42. Ganes T, Lundar T 1983 The effect of thiopentone on somatosensory evoked responses and EEGs in comatose patients. J Neurol Neurosurg Psychiatry 46:509-514
43. Strom J, Haggmark S, Reiz S, Sorensen MB 1987 Cardiovascular effects of pentobarbital in pigs, and the lack of response to naloxone in pentobarbital induced circulatory failure. Acta Anaesthesiol Scand 31:413-416
44. Haworth SG, Hislop AA 1981 Adaptation of the pulmonary circulation to extra-uterine life in the pig and its relevance to the human infant. Cardiovasc Res 15:108-119
45. Laptook A, Stonestreet BS, Oh W 1982 The effects of different rates of plasmanate infusions upon brain blood flow after asphyxia and hypotension in newborn piglets. J Pediatr 100:791-796