Autonomic effects of nicotine patch administration in habitual cigarette smokers: A double-blind, placebo-controlled study using spectral analysis of RR interval and systolic arterial pressure variabilities

Journal of Cardiovascular Pharmacology

Volumn 31, Issue 5, 1998, Pages 714-720

  Lucini, Daniela ^b   Bertocchi, Federico ^b   Malliani, Alberto ^b   Pagani, Massimo ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b NONE

Author keywords

Autonomic; Nervous system; Prevention; Risk factors; Smoking

Indexed keywords

NICOTINE;

ADULT; ARTICLE; CARDIOVASCULAR AUTOREGULATION; CARDIOVASCULAR EFFECT; CIGARETTE SMOKING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; HEART RATE VARIABILITY; HUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RR INTERVAL; SMOKING CESSATION; TRANSDERMAL DRUG ADMINISTRATION;

ADMINISTRATION, CUTANEOUS; ADULT; ANALYSIS OF VARIANCE; AUTONOMIC NERVOUS SYSTEM; BLOOD PRESSURE; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; ELECTROCARDIOGRAPHY; GANGLIONIC STIMULANTS; HUMANS; NICOTINE; RISK FACTORS; SMOKING;

EID: 0031956987     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199805000-00010     Document Type: Article

References (39)

1. Hayano J, Yamada M, Sakakibara Y, et al. Short-and long-term effects of cigarette smoking on heart rate variability. Am J Cardiol 1990;65:84-8.
2. Lucini D, Bertocchi F, Malliani A, Pagani M. A controlled study of the autonomic changes produced by habitual cigarette smoking in healthy subjects. Cardiovasc Res 1996;31:633-9.
3. Wannamethee SG, Shaper G, Whincup PH, Walker M. Smoking cessation and the risk of stroke in middle-aged men. JAMA 1995;274:155-60.
4. Manson JE, Tosteson H, Ridker PM, et al. The primary prevention of myocardial infarction. N Engl J Med 1992;326:1406-16.
5. Friedman GD, Petitti DB, Bawol RD, Siegelaub AB. Mortality in cigarette smokers and quitters: effects of baseline differences. N Engl J Med 1981;304:1407-10.
6. Rosenberg L, Kaufman DW, Helmrich SP, Shapiro S. The risk of myocardial infarction after quitting smoking in men under 55 years of age. N Engl J Med 1985;313:1511-4.
7. Rosenberg L, Palmer JR, Shapiro S. Decline in the risk of myocardial infarction among women who stop smoking. N Engl J Med 1990;322:213-7.
8. Salonen JT. Stopping smoking and long-term mortality after acute myocardial infarction. Br Heart J 1980;43:463-9.
9. Sleight P. After the diagnosis of systemic hypertension, is risk factor management important? Am J Cardiol 1992;70:9-13D.
10. Peters RW, Brooks MM, Todd L, Liebson PR, Wilhelmsen L. Smoking cessation and arrhythmic death, the cast experience. J Am Coll Cardiol 1995;26:1287-92.
11. Hallstrom AP, Cobb LA, Ray R. Smoking as a risk factor for recurrence of sudden cardiac arrest. N Engl J Med 1986;314:271-5.
12. Henningfield JE. Nicotine education for smoking cessation. N Engl J Med 1995;333:1196-203.
13. Hardman JG, Limbird LE, eds. Goodman and Gilman's the pharmacological basis of therapeutics. 9th ed. New York: McGraw-Hill, 1996.
14. Julius S. Sympathetic hyperactivity and coronary risk in hypertension. Hypertension 1993;21:886-93.
15. Muller JE, Tofler GH, Verrier RL. Sympathetic activity as the cause of the morning increase in cardiac events: a likely culprit, but the evidence remains circumstantial. Circulation 1995;91:2508-9.
16. Lucini D, Mela GS, Malliani A, Pagani M. Evidence of increased sympathetic vasomotor drive with shorter acting dihydropyridine calcium channel antagonists in human hypertension: a study employing spectral analysis of RR interval and systolic arterial pressure variability. J Cardiovasc Pharmacol 1997;29:676-83.
17. Niedermaier ON, Smith ML, Beightol LA, et al. Influence of cigarette smoking on human autonomic function. Circulation 1993;88:562-71.
18. Fagestrom KO. Measuring degree of physical dependence to tobacco smoke with reference to individualization or treatment. Addict Behav 1978;3:235-41.
19. Green MS, Jucha E, Luz J. Blood pressure in smokers and non-smokers: epidemiologic findings. Am Heart J 1986;111:932-9.
20. Grassi G, Seravalle G, Calhoun DA, et al. Mechanisms responsible for sympathetic activation by cigarette smoking in humans. Circulation 1994;90:248-53.
21. Mulligan SC, Masterson JG, Devane JG, Kelly JG. Clinical and pharmacokinetics properties of a transdermal nicotine patch. Clin Pharmacol Ther 1990;47:331-7.
22. Furlan R, Piazza S, Dell'Orto S, et al. Aftereffects of exercise and athletic training on neural mechanisms controlling heart period. Cardiol Res 1993;27:482-8.
23. Pagani M, Rimoldi O, Pizzinelli P, et al. Assessment of the neural control of the circulation during psychological stress. J Auton Nerv Syst 1991;35:33-42.
24. Pagani M, Lombardi F, Guzzetti S, et al. Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog. Circ Res 1986;59:178-93.
25. Malliani A, Pagani M, Lombardi F, Cerutti S. Advances in research series: cardiovascular neural regulation explored in the frequency domain. Circulation 1991;84:482-92.
26. Pagani M, Montano N, Porta A, et al. Relationship between spectral components of cardiovascular variabilities and direct measure of muscle sympathetic nerve activity in humans. Circulation 1997;95:1441-8.
27. Cerutti S, Baselli G, Civardi S, et al. Spectral analysis of heart rate and arterial blood pressure variability signals for physiological and clinical purposes. In: Computers in cardiology. Silver Springs, MD: IEEE Computer Society Press, 1987:435-8.
28. Pagani M, Somers V, Furlan R, et al. Changes in autonomic regulation induced by physical training in mild hypertension. Hypertension 1988;12:600-10.
29. Lucini D, Pagani M, Mela GS, Malliani A. Sympathetic restraint of baroreflex control of heart period in normotensive and hypertensive subjects. Clin Sci 1994;86:547-56.
30. Malliani A, Pagani M, Furlan R, et al. Individual recognition by heart rate variability of two different autonomic profiles related to posture. Circulation 1997;96:4143-5.
31. Benowitz AL, Fitzgerald GA, Wilson M, Zhang Q. Nicotine effects on eicosanoid formation and hemostatic function: comparison of transdermal nicotine and cigarette smoking. J Am Coll Cardiol 1993;22:1159-67.
32. Lee LY, Gerharfstein DC, Wang AL, Burki NK. Nicotine is responsible for airway irritation evoked by cigarette smoke inhalation in men. J Appl Physiol 1993;75:1955-61.
33. Lombardi F, Malliani A, Pagani M. Nervous activity of afferent sympathetic fibers innervating the pulmonary vein. Brain Res 1976;113:197-200.
34. Malliani A, Pagani M, Lombardi F. Positive feedback reflexes In: Zanchetti A, Tarazi RC, eds. Handbook of hypertension vol 8: pathophysialogy of hypertension-regulatory mechanisms. Amsterdam: Elsevier Science Publishing, 1986:69-81.
35. Joseph AM, Norman SM, Ferry LH, et al. The safety of transdermal nicotine as an aid to smoking cessation in patients with cardiac disease. N Engl J Med 1996;335:1792-8.
36. Kottke TE. Smoking cessation therapy for the patient with heart disease. J Am Coll Cardiol 1993;22:1168-9.
37. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology: Heart Rate Variability. Standards of measurements, physiological interpretation, and clinical use. Circulation 1996;93:1043-65.
38. Lakier JB. Smoking and cardiovascular disease. Am J Med 1992; 93(suppl 1A):8-12S.
39. Working Group for the Study of Transdermal Nicotine in Patients with Coronary Artery Disease. Nicotine replacement therapy for patients with coronary artery disease. Arch Intern Med 1994; 154:989-95.