Comparison of the effect of etomidate and desflurane on brain tissue gases and pH during prolonged middle cerebral artery occlusion

Anesthesiology

Volumn 88, Issue 5, 1998, Pages 1188-1194

  Huffman, William E ^a,b   Charbel, Fady T ^a   Edelman, Guy ^a   Misra, Mukesh ^a   Ausman, James I ^a  

^a Department of Anesthesiology ^*

^b UNIVERSITY OF ILLINOIS HOSPITAL AND HEALTH SCIENCES SYSTEM   (United States)

Author keywords

Anesthesia; Anesthetics; Intravenous; Ischemia; Neuroanesthesia; Volatile

Indexed keywords

DESFLURANE; ETOMIDATE;

ADULT; AGED; ARTICLE; BRAIN ISCHEMIA; BRAIN OXYGEN TENSION; CARBON DIOXIDE TENSION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; INHALATION ANESTHESIA; INHALATIONAL DRUG ADMINISTRATION; INTRAVENOUS ANESTHESIA; INTRAVENOUS DRUG ADMINISTRATION; LASER DOPPLER FLOWMETRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROMODULATION; PH; PRIORITY JOURNAL;

ADULT; AGED; ANESTHETICS, INHALATION; ANESTHETICS, INTRAVENOUS; ANOXIA; BRAIN; CARBON DIOXIDE; CEREBRAL ARTERIES; CONSTRICTION; ETOMIDATE; FEMALE; HEMODYNAMIC PROCESSES; HUMANS; HYDROGEN-ION CONCENTRATION; ISOFLURANE; MALE; MIDDLE AGED; OXYGEN CONSUMPTION;

EID: 0031956634     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199805000-00008     Document Type: Article

References (27)

1. Samson D, Batjer HH, Bowman G, Mootz L, Krippner WJ Jr, Meyer YJ, Allen BC: A clinical study of the parameters and effects of temporary arterial occlusion in the management of intracranial aneurysms. Neurosurgery 1994; 34:22-9
2. Michenfelder JD: The interdependency of cerebral functional and metabolic effects following massive doses of thiopental in the dog. ANESTHESIOLOGY 1974; 40:575-80
3. Cole DJ, Drummond JC, Patel PM, Jacobsen WK: Etomidate, nitric oxide, and cerebral ischemic injury. J Neurosurg Anesth 1996; 8:329-35
4. Drummond JC, Cole DJ, Patel PM, Reynolds LW: Focal cerebral ischemia during anesthesia with etomidate, isoflurane or thiopental: A comparison of the extent of cerebral injury. Neurosurgery 1995; 37:742-9
5. Lutz LJ, Milde JH, Milde LN: The cerebral functional, metabolic and hemodynamic effects of desflurane in dogs. ANESTHESIOLOGY 1990; 73:125-31
6. Seyde WC, Longnecker DE: Cerebral oxygen tension in rats during deliberate hypotension with sodium nitroprusside, 2-chlororadenosine, or deep isoflurane anesthesia. ANESTHESIOLOGY 1986; 64:480-5
7. Hoffman WE, Charbel FT, Edelman G: Desflurane increases brain tissue oxygenation and pH. Acta Anaesth Scand 1997; 41:1162-6
8. Rampil IJ, Lockhart SH, Eger EI II, Yoshuda N, Weiskopf RB, Calahan MK: The electroencephalographic effects of desflurane in humans. ANESTHESIOLOGY 1991; 74:434-9
9. Hoffman WE, Edelman G: Comparison of isoflurane and desflurane anesthetic depth using burst suppression of the electroencephalogram in neurosurgical patients. Anesth Analg 1995; 81:811-6
10. Hoffman WE, Charbel FT, Edelman G: Brain tissue oxygen, carbon dioxide, and pH in neurosurgical patients at risk for ischemia. Anesth Analg 1996; 82:682-6
11. Edelman G, Huffman WE, Charbel FT: Cerebral hypoxia following etomidate administration and temporary cerebral artery occlusion. Anesth Analg 1997; 85:821-5
12. Milde LN, Milde JH, Michenfelder JD: Cerebral functional, metabolic and hemodynamic effects of etomidate in dogs. ANESTHESIOLOGY 1985; 63:371-7
13. Davis DW, Mans AM, Biebuyck JF, Hawkins RA: Regional brain glucose utilization in rats during etomidate anesthesia. ANESTHESIOLOGV 1986; 64:751-7
14. Frizzell RT, Meyer YJ, Borchers DJ, Weprin BE, Allen EC, Pogue WR, Reisch JS, Cherrington AD, Batjer HH: The effects of etomidate on cerebral metabolism and blood flow in a canine model for hypotension. J Neurosurg 1991; 74:263-9
15. Renou AM, Vernhiet J, Macrez P, Constant P, Billerey J, Khadaroo MY, Caille JM: Cerebral blood flow and metabolism during etomidate anaesthesia in man. Br J Anaesth 1978; 50:1047-51
16. Van Reempts J, Borgers M, Eyndhoven, Hermans C: Protective effects of etomidate in hypoxic-ischemic brain damage in the rat: A morphologic assessment. Exp Neurol 1982; 76:181-95
17. Wauquier A, Ashton D, Clinke G, Niemegeers JE: Anti-hypoxic effects of etomidate, thiopental and methohexital. Arch Int Pharmacodyn 1981; 249:330-4
18. Guo J, White JA, Batjer HH: Limited protective effects of etomidate during brainstem ischemia in dogs. J Neurosurg 1995; 82:278-83
19. Sano T, Patel PM, Drummond JC, Cole DJ: A comparison of the cerebral protective effects of etomidate, thiopental, and isoflurane in a model of forebrain ischemia in the rat. Anesth Analg 1993; 76:990-7
20. Watson JC, Drummond JC, Patel PM, Sano T, Akrawi W, Sang H: An assessment of the cerebral protective effects of etomidate in a model of incomplete forebrain ischemia in the rat. Neurosurgery 1992; 30:540-4
21. Smith DS, Keykah MM, O'Neill JJ, Harp JR: The effect of etomidate pretreatment on cerebral high energy metabolites, lactate, and glucose during severe hypoxia in the rat. ANESTHESIOLOGY 1989; 71:438-43
22. Milde LN, Milde JH: Preservation of cerebral metabolites by etomidate during incomplete cerebral ischemia in dogs. ANESTHESIOLOGY 1986; 65:272-7
23. 2 in the brain. Acta Physiol Scand 1966; 67:129-40
24. Newberg L, Milde L, Milde JH: The cerebral and systemic hemodynamic and metabolic effects of desflurane-induced hypotension in dogs. ANESTHESIOLOGY 1991; 74:513-8
25. Stebel S, Lam AM, Matta B, Mayberg TS, Aaslid R, Newell DW: Dynamic and static cerebral autoregulation during isoflurane, desflurane, and propofol anesthesia. ANESTHESIOLOGY 1995; 83:66-76
26. Talke P, Caldwell J, Dodson B, Richardson CA: Desflurane and isoflurane increase lumbar cerebrospinal fluid pressure in normocapnic patients undergoing transphenoidal hypophysectomy. ANESTHESIOLOGY 1996; 85:999-1004
27. Artru AA, Powers KM: Furosemide decreases cerebrospinal fluid formation during desflurane anesthesia in rabbits. J Neurosurg Anesth 1997; 9:166-74