Reversal of multidrug resistance by a liposome-MDR1 ribozyme complex

Cancer Chemotherapy and Pharmacology

Volumn 42, Issue 1, 1998, Pages 9-16

  Masuda, Yoshihiro ^a   Kobayashi, Hiroyuki ^b   Holland, James F ^a   Ohnuma, Takao ^a,c  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^c MOUNT SINAI MEDICAL CENTER   (United States)

Author keywords

Cationic liposome; Endocytosis; MDR1; Multidrug resistance; Ribozyme

Indexed keywords

DOXORUBICIN; GLYCOPROTEIN P; LIPOSOME; MESSENGER RNA; RIBOZYME; TRIMETREXATE; VINCRISTINE;

ARTICLE; BREAST CANCER; CELL LINE; CELL VACUOLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOLOGY; ENDOCYTOSIS; GENE EXPRESSION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; DRUG RESISTANCE, MULTIPLE; DRUG SCREENING ASSAYS, ANTITUMOR; ENDOCYTOSIS; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; HUMANS; LIPOSOMES; MICROSCOPY, CONFOCAL; MICROSCOPY, PHASE-CONTRAST; P-GLYCOPROTEIN; RNA, CATALYTIC; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0031956591     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050778     Document Type: Article

References (22)

1. Ling V (1985) Multidrug resistant mutants. In: Gottesman MM (ed) Molecular cell genetics. John Wiley, New York, p 773
2. Pastan I, Gottesman MM (1987) Multiple-drug resistance in human cancer. N Engl J Med 316: 1388
3. Croop JM, Gros P, Housman DE (1988) Genetics of multidrug resistance. J Clin Invest 81: 1303
4. Endicott JA, Ling V (1989) The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu Rev Biochem 58: 137
5. Fuqua SAW, Morreti-Rojas IM, Schneíder SL, McGuire WL (1987) P-glycoprotein expression in human breast cancer cells. Cancer Res 47: 2103
6. Lemontt JF, Azzaria M, Gros P (1988) Increased mdr gene expression and decreased drug accumulation in multidrug-resistant human melanoma cells. Cancer Res 48: 6348
7. Li X-K, Kobayashi H, Holland JF, Ohnuma T (1993) Expression of dihydrofolate reductasc and multidrug resistance genes in trimetrexate-resistant human leukemia cell lines. Leuk Res 17: 483
8. Cech TR (1988) Ribozymes and their medical implications. JAMA 260: 3030
9. Haseloff J, Gerlach WJ (1988) Simple RNA enzymes with new and highly specific endoribonuclease activities. Nature 334: 585
10. Marschall P, Thomson JB, Eckstein F (1994) Inhibition of gene expression with ribozymes. Cell Mol Neurobiol 14: 523
11. Kobayashi H, Dorai T, Holland JF, Ohnuma T (1994) Reversal of drug sensitivity in multidrug-resistant tumor cells by an MDR1 (PGY1) ribozyme. Cancer Res 54: 1271
12. Holm PS, Scanlon KJ, Dietel M (1994) Reversion of multidrug resistance in the P-glycoprotein-positive human pancreatic cell line (9EPP85-181RDB) by introduction of a hammerhead ribozyme. Br J Cancer 70: 239
13. Cowan KH, Batist G, Tulpule A, Sinha B, Myers CE (1986) Similar biochemical changes associated with multidrug resistance in human breast cancer cells and carcinogen-induced resistance to xenobiotics in rats. Proc Natl Acad Sci USA 83: 9328
14. Minowada J, Ohnuma T, Moore GE (1972) Rosette-forming human lymphoid cell lines: 1. Establishment and evidence for origin of thymus-derived lymphocytes. J Natl Cancer Inst 49: 891
15. Milligan JF, Groebe DR, Witherell GW, Uhlenbeck OC (1987) Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates. Nucl Acids Res 15: 8783
16. Felgner PL, Ringold GM (1989) Cationic liposome-mediated transfection. Nature 337: 387
17. Takigawa N, Danno K, Furukawa F (1987) Effect of colchicine and cytochalasin B on distribution of concanavalin A receptors in isolated and cultured guinea pig epidermal cells. Arch Dermatol Res 279: 392
18. Finbloom DS, Martin J, Gordon RK (1987) Endocytosis of particulate and soluble IgG immune complexes: differential effects ol cytoskeletal modulating agents. Clin Exp Immunol 67: 205
19. Huang L, Farhood H, Serbina N, Teepe AG, Barsoum J (1995) Endosomolytic activity of cationic liposomes enhances the delivery of human immunodeficiency virus-1 transactivator protein (TAT) to mammalian cells. Biochem Biophys Res Commun 217: 761
20. Kiehntopf M, Brach MA, Licht T, Petschauer S, Karawajew L, Kirschning C, Herrmann F (1994) Ribozyme-mediated cleavage of the MDR1 transcript restores chemosensitivity in previously resistant cancer cells. EMBO J 13: 4645
21. Bonnekoh B, Roeding J, Krueger GRF, Ghyczy M, Mahrle G (1991) Increase of lipid fluidity and suppression of proliferation resulting from liposome uptake by human keratinocytes in vitro. Br J Dermatol 124: 333
22. Veras PST, de Chastellier C, Moreau M-F, Villers V, Thibon M, Mattei D, Rabinovitch M (1994) Fusion between large phagocytic vesicles: targeting of yeast and other particulates to phagolysosomes that shelter the bacterium Coxiella burnetii or the protozoan Leishmania amazonesis in Chinese hamster ovary cells. J Cell Sci 107: 3065