Short synthesis of 2,4-disubstituted 1,3-oxathiolane and 1,3-dithiolane cytosine nucleosides: Facile introduction of a 4-benzoate group using benzoyl peroxide

Synthesis

Volumn , Issue 5, 1998, Pages 759-762

  Nguyen Ba, Nghe ^a   Brown, William ^a   Lee, Nola ^a   Zacharie, Boulos ^a  

^a Shire Canada   (Canada)

Author keywords

1,3 Dithiolane; 1,3 Oxathiolane; Benzoate as leaving group; Benzoyl peroxide; cis Nucleoside analogs selectively; Pyrimidine bases; TMSI

Indexed keywords

1,3 DITHIOLANE DERIVATIVE; 1,3 OXATHIOLANE DERIVATIVE; 4 BENZOYLOXY 2 BENZOYLOXYMETHYL 1,3 DITHIOLANE; BENZOYL PEROXIDE; CYTOSINE DERIVATIVE; DIDANOSINE; LAMIVUDINE; PYRIMIDINE NUCLEOSIDE DERIVATIVE; STAVUDINE; UNCLASSIFIED DRUG; ZALCITABINE; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; DRUG SYNTHESIS; HEPATITIS B VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; NUCLEOTIDE METABOLISM; STEREOCHEMISTRY;

EID: 0031955571     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1998-2065     Document Type: Article

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