Synthesis of [123I]-8-[4-[2-(5-iodothienyl)]-4-oxobutyl]-3-methyl-1- phenyl-1,3,8-triazaspiro[4.5]decan-4-one: A potential dopamine D2 receptor radioligand for SPECT

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 41, Issue 5, 1998, Pages 363-376

  Waterhouse, Rikki N ^a,d   Gotsick, J Timothy ^b   Kabalka, George W ^b   Goodman, Mark M ^c   O'Brien, J C ^d  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROPHYSIOLOGY;

DOPAMINE; HIGH AFFINITY; IN-VITRO; LIPOPHILICITY; POTENTIAL LIGAND; RADIOCHEMICAL YIELD; RADIOLIGANDS; SPECIFIC ACTIVITY; SYNTHESISED; THIENYL;

AMINES;

8 [4 [2 (5 IODOTHIENYL)] 4 OXOBUTYL] 3 METHYL 1 PHENYL 1,3,8 TRIAZASPIRO[4.5]DECAN 4 ONE; DOPAMINE 2 RECEPTOR; IODINE 123; RADIOLIGAND; UNCLASSIFIED DRUG;

ARTICLE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; LIPOPHILICITY; PROTON NUCLEAR MAGNETIC RESONANCE; RADIOIODINATION; RECEPTOR AFFINITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SYNTHESIS;

EID: 0031955523     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1344(199805)41:5<363::AID-JLCR90>3.0.CO;2-B     Document Type: Article

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