Diastereoselective syntheses of N-protected derivatives of 1α,5α,6β- 6-amino-3-azabicyclo[3.1.0]hexane; a route to trovafloxacin 6β-diastereomer

Synthesis

Volumn , Issue 5, 1998, Pages 739-744

  Vilsmaier, Elmar ^a   Goerz, Torsten ^a  

^a Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

Author keywords

Chloroenamines; N protected 1 ,5 ,6 6 amino 3 azabicyclo 3.1.0 hexanes; Synthesis; Trovafloxacin 6 diastereomer

Indexed keywords

1ALPHA,5ALPHA,6BETA 6 (DIBENZYLAMINO) 3 AZABICYCLO[3.1.0]HEXANE; 1ALPHA,5ALPHA,6BETA 6 AMINO 3 (METHOXYCARBONYL) 3 AZABICYCLO[3.1.0]HEXANE; 1ALPHA,5ALPHA,6BETA 6 AMINO 3 BENZYL 3 AZABICYCLO[3.1.0]HEXANE; 3 AZABICYCLO[3.1.0]HEXANE DERIVATIVE; 7 (1ALPHA,5ALPHA,6BETA 6 AMINO 3 AZABICYCLO[3.1.0]HEX 3 YL) 1 (2,4 DIFLUOROPHENYL) 6 FLUORO 4 OXO 1,4 DIHYDRO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; DIBENZYLAMINE; GYRASE INHIBITOR; NAPHTHYRIDINE DERIVATIVE; TROVAFLOXACIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL INFECTION; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; PENICILLIN RESISTANCE; STEREOCHEMISTRY; STREPTOCOCCUS PNEUMONIAE;

EID: 0031955493     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1998-2055     Document Type: Article

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