Smoking alters the phenotype of macrophages in induced sputum

Respiratory Medicine

Volumn 92, Issue 3, 1998, Pages 415-420

  Lensmar, C ^a   Elmberger, G ^a   Skold M ^a   Eklund, A ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD68 ANTIGEN; CD71 ANTIGEN; HLA DR ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; MONOCLONAL ANTIBODY; SODIUM CHLORIDE;

ANTIGEN PRESENTATION; ARTICLE; CELL COUNT; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IMMUNOHISTOCHEMISTRY; INHALATION; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE; NEUTROPHIL; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; SMOKING; SPUTUM;

EID: 0031955295     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0954-6111(98)90284-0     Document Type: Article

References (22)

1. Poulter LW. Changes in lung macrophages during disease. FEMS Microbiol Immunol 1990; 64: 327-332.
2. Spiteri MA, Poulter LW. Characterization of immune inducer and suppressor macrophages from the normal human lung. Clin Exp Immunol 1991; 83: 157-162.
3. Strickland DH, Thepen T, Kees UR, Kraal G, Holt PG. Regulation of T-cell function in lung tissue by pulmonary alveolar macrophages. Immunology 1993; 80: 266-272.
4. Strickland DH, Kees UR, Holt PG. Suppression of T-cell activation by pulmonary alveolar macrophages: dissociation of effects on TcR, IL-2R expression, and proliferation. Eur Respir J 1994; 7: 2124-2130.
5. Montefort S, Holgate ST. Adhesion molecules and their role in inflammation. Respir Med 1991; 85: 91-99.
6. Sköld CM, Eklund A, Hallden G, Hed J. Autofluorescence in human alveolar macrophages from smokers: relation to cell surface markers and phagocytosis. Exp Lung Res 1989; 15: 823-835.
7. Nakstad B, Lyberg T, Skjörten F, Boye NP. Subpopulations of human lung alveolar macrophages: ultrastructural features. Ultrastruct Pathol 1989; 13: 1-13.
8. Schaberg T, Lauer C, Lode H, Fischer J, Haller H. Increased number of alveolar macrophages expressing adhesion molecules of the leucocyte adhesion molecule family in smoking subjects. Am Rev Respir Dis 1992; 146: 1287-1293.
9. Costabel U, Guzman J. Effect of smoking on bronchoalveolar lavage constituents. Editorial. Eur Respir J 1992; 5: 776-779.
10. Hoogsteden HC, van Hal PThW, Wijkhuijs JM, Hop W, Verkaik APK, Hilvering C. Expression of the CD11/CD18 cell surface adhesion glycoprotein family on alveolar macrophages in smokers and nonsmokers. Chest 1991; 100: 1567-1571.
11. Mancini NM, Béné MC, Gérard H et al. Early effects of short-time cigarette smoking on the human lung: a study of bronchoalveolar lavage fluids. Lung 1993; 171: 277-291.
12. Pankow W, Neumann K, Rüschoff J, Schröder R, von Wiehert P. Reduction in HLA-DR antigen density on alveolar macrophages of smokers. Lung 1991; 169: 255-262.
13. Fahy JV, Liu J, Wong H, Boushey HA. Cellular and biochemical analysis of induced sputum from asthmatics and from healthy subjects. Am Rev Respir Dis 1993; 147: 1126-1131.
14. Iredale MJ, Wanklyn SAR, Phillips IP, Krausz T, Ind PW. Non-invasive assessment of bronchial inflammation in asthma: no correlation between eosinophilia of induced sputum and bronchial responsiveness to inhaled hypertonic saline. CHn Exp All 1994; 24: 940-945.
15. Keatings VM, Collins PD, Scott DM, Barnes PJ. Differences in interleukin-8 and tumour necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med 1996; 153: 530-534.
16. Sköld CM, Lundahl J, Hallden G, Hallgren M, Eklund A. Chronic smoke exposure alters the phenotype pattern and the metabolic response in human airway macrophages. Clin Exp Immunol 1996; 106: 108-113.
17. Stríz I, Wang YM, Svarcová I, Trnka L, Sorg C, Costabel U. The phenotype of alveolar macrophages and its correlation with immune cells in bronchoalveolar lavage. Eur Respir J 1993; 6: 1287-1294.
18. Striz I, Wang YM, Kalaycioglu O, Costabel U. Expression of alveolar macrophage adhesion molecules in pulmonary sarcoidosis. Chest 1992; 102: 882-886.
19. Melis M, Gjomarkaj M, Pace E, Malizia G, Spatafora M. Increased expression of leucocyte function associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1) by alveolar macrophages of patients with sarcoidosis. Chest 1991; 100: 910-916.
20. Haslam PL, Parker DJ, Townsend PJ. Increases in HLA-DQ, DP, DR and transferrin receptors on alveolar macrophages in sarcoidosis and allergic alveolitis compared with fibrosing alveolitis. Chest 1990; 97: 651-661.
21. Holt PG. Regulation of antigen-presenting cell function(s) in lung and airway tissues. Review. Eur Respir J 1993; 6: 120-129.
22. Rankin JA, Marcy T, Rochester CL et al. Human airway macrophages. Am Rev Respir Dis 1992; 145: 928-933.