Benzocaine-induced methemoglobinemia complicating transesophageal echocardiography: A case report

Echocardiography

Volumn 15, Issue 4, 1998, Pages 389-391

  McGrath, Paul D ^a   Moloney, John F ^a   Riker, Richard R ^a  

^a MAINE MEDICAL CENTER   (United States)

Author keywords

Benzocaine; Methemoglobinemia; Transesophageal echocardiography

Indexed keywords

BENZOCAINE; CIMETIDINE; DROPERIDOL; HEPARIN; HYDROCORTISONE; METHEMOGLOBIN; METHYLENE BLUE; MIDAZOLAM; MORPHINE;

ADULT; ARTICLE; CASE REPORT; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LEG ISCHEMIA; METHEMOGLOBINEMIA; OXYGEN SATURATION; PRIORITY JOURNAL; THROMBECTOMY; TRANSESOPHAGEAL ECHOCARDIOGRAPHY;

EID: 0031955139     PISSN: 07422822     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1540-8175.1998.tb00622.x     Document Type: Article

References (15)

1. Barker SJ, Tremper KK, Hyatt J: Effects of methemoglobinemia on pulse oximetry and mixed venous oximetry. Anesthesiology 1989; 70:112-117.
2. Brown CM, Levy SA, Susann PW: Methemoglobinemia: Life-threatening complication of endoscopy premedication. Am J Gastroenterol 1994;89:1108-1109.
3. Dinneen SF, Mohr DN, Fairbanks VF: Methemoglobinemia from topically applied anesthetic spray. Mayo Clin Proc 1994;69:886-888.
4. O'Donohue WJ, Moss LM, Angelillo VA: Acute methemoglobinemia induced by topical benzocaine and lidocaine. Arch Intern Med 1980; 140:1508-1509.
5. Rodriquez LF, Smolik LM, Zbehlik AJ: Benzocaine-induced methemoglobinemia: Report of a severe reaction and review of the literature. Ann Pharmacother 1994;28:643-649.
6. Marcovitz PA, Williamson BD, Armstrong WF: Toxic methemoglobinemia caused by topical anesthetic given before transesophageal echocardiography. J Am Soc Echocardiogr 1991;4: 615-618.
7. Grauer SE, Giraud GD: Toxic methemoglobinemia after topical anesthesia for transesophageal echocardiography. J Am Soc Echocardiogr 1996;9:874-876.
8. Beutler E: Methemoglobinemia and other causes of cyanosis. In Beutler E, Lichtman MA, Coller BS, et al (eds): William 's Hematology, ed 5. McGraw-Hill, New York, 1995, pp. 654-663.
9. Douglas WW, Fairbanks VF: Methemoglobinemia induced by topical anesthetic spray. Chest 1977;71:587-591.
10. Jaffe ER, Hultquist DE: Cytochrome b5 reductase deficiency and enzymopenic hereditary methemoglobinemia. In Scriver CR, Beaudet AL, Sly WS, et al (eds): The Metabolic Basis of Inherited Disease, ed 6. McGraw-Hill, New York, 1989, pp. 2267-2280.
11. Guertler AT, Pearce WA: A prospective evaluation of benzocaine-associated methemoglobinemia in human beings. Ann Emerg Med 1994; 24:626-630.
12. Luckens JN: Methemoglobinemia and other disorders accompanied by cyanosis. In Lee GR, Bithell TC, Foerster J, et al (eds): Wintrobe's Clinical Hematology, ed 9. Lea & Febiger, Philadelphia, 1993, pp. 1262-1271.
13. Curry S: Methemoglobinemia. Ann Emerg Med 1982;11:214-221.
14. Council on Scientific Affairs, American Medical Association. The use of pulse oximetry during conscious sedation. JAMA 1993;270:1463-1467.
15. Guidelines for monitoring and management of pediatric patients during and after sedation for diagnostic and therapeutic procedures. Pediatrics 1992;89:1110-1115.