Immunohistochemical measurement of cell proliferation as replicative DNA synthesis in the liver of male Fischer 344 rats following a single exposure to nongenotoxic hepatocarcinogens and noncarcinogens

Experimental and Toxicologic Pathology

Volumn 50, Issue 1, 1998, Pages 13-17

  Ohtsuka, Masanori ^a,b   Fukuda, Kazunori ^a   Yano, Hirohisa ^a   Kojiro, Masamichi ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b CHEMICALS EVALUATION AND RESEARCH INSTITUTE   (Japan)

Author keywords

Bromodeoxyuridine immunohistochemistry; Carcinogenicity assay; Cell proliferation, measurement; Dose response studies; Hepatocarcinogens, nongenotoxic; Liver, cell proliferation; Nongenotoxic hepatocarcinogens; Replicative DNA synthesis

Indexed keywords

ASCORBIC ACID; BROXURIDINE; CARBON TETRACHLORIDE; CARCINOGEN; CHLOROFORM; CLOFIBRATE; DIETHYLSTILBESTROL; ETHINYLESTRADIOL; ETHIONINE; LITHOCHOLIC ACID; MANNITOL; PHENOBARBITAL; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; SAFROLE; TANNIN; THIOACETAMIDE; THYMIDINE; TRYPTOPHAN; URETHAN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CARCINOGEN TESTING; CARCINOGENICITY; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DNA REPLICATION; DNA SYNTHESIS; DOSE RESPONSE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LIVER CARCINOGENESIS; LIVER HISTOLOGY; LIVER NECROSIS; LIVER REGENERATION; LIVER TOXICITY; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; TECHNIQUE;

ANIMALIA;

EID: 0031954587     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0940-2993(98)80054-7     Document Type: Article

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