Cell cycle arrest in Era GTPase mutants: A potential growth rate-regulated checkpoint in Escherichia coli

Molecular Microbiology

Volumn 27, Issue 4, 1998, Pages 739-750

  Britton, Robert A ^a,d   Powell, Bradford S ^b   Dasgupta, Santanu ^b,e   Sun, Qin ^c   Margolin, William ^c   Lupski, James R ^a   Court, Donald L ^b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; GUANOSINE TRIPHOSPHATASE; RIBONUCLEASE III;

ALLELE; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIUM MUTANT; CELL CYCLE; CELL DIVISION; CELL VIABILITY; CHROMOSOME REPLICATION; CONTROLLED STUDY; ESCHERICHIA COLI; GROWTH RATE; NONHUMAN; OPERON; PRIORITY JOURNAL; PROTEIN EXPRESSION; TEMPERATURE;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CELL CYCLE; CELL DIVISION; CYTOSKELETAL PROTEINS; DNA REPLICATION; DNA TRANSPOSABLE ELEMENTS; ENDORIBONUCLEASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; RIBONUCLEASE III; RNA-BINDING PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TEMPERATURE;

EID: 0031953140     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1998.00719.x     Document Type: Article

References (46)

1. Addinall, S.G., Bi, E., and Lutkenhaus, J. (1996) FtsZ ring formation in fis mutants. J Bacteriol 178: 3877-3844.
2. Ahnn, J., March, P.E., Takiff, H.E., and Inouye, M. (1986) A GTP-binding protein of Escherichia coli has homology to yeast RAS proteins. Proc Natl Acad Sci USA 83: 8849-8853.
3. Altschul, S.F., Gish, W., Miller, W., Myers, E.W., and Lipman, D.J. (1990) Basic local alignment search tool. J Mol Biol 215: 403-410.
4. Anderson, P.E., Matsunaga, J., Simons, E.L., and Simons, R.W. (1996) Structure and regulation of the Salmonella typhimurium rnc-era-recO operon. Biochimie 78: 1025-1034.
5. Bardwell, J.C.A., Regnier, P., Chen, S.-M., Nakamura, Y., Grunberg-Manago, M., and Court, D.L. (1989) Autoregulation of RNase III operon by mRNA processing. EMBO J 8: 3401-3407.
6. Bi, E., and Lutkenhaus, J. (1992) FtsZ structure associated with cell division in Escherichia coli. Nature 354: 161-164.
7. Bourne, H.R., Sanders, D.A., and McCormick, F. (1991) The GTPase superfamily: conserved structure and molecular mechanism. Nature 349: 117-127.
8. Bramhill, D., and Thompson, C.M. (1994) GTP-dependent polymerization of Escherichia coli FtsZ protein to form tubules. Proc Natl Acad Sci USA 91: 5813-5817.
9. Bremer, H., and Dennis, P.P. (1987) Modulation of chemical composition and other parameters of the cell by growth rate. In Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology. Neidhardt, F.C., Ingraham, J.L., Low, K.B., Magasanik, B., Schaechter, M., and Umbarger, H.E. (eds). Washington, DC: American Society for Microbiology Press, pp. 1527-1542.
10. Britton, R.A., and Lupski, J.R. (1997) Isolation and characterization of suppressors of two Escherichia coli dnaG mutations, dnaG2903 and parB. Genetics 145: 867-875.
11. Britton, R.A., Powell, B.S., Court, D.L., and Lupski, J.R. (1997) Characterization of mutations affecting the Escherichia coli essential GTPase Era that suppress two temperature-sensitive dnaG alleles. J Bacteriol 179: 4575-4582.
12. Chen, S.-M., Takiff, H.E., Barber, A.M., Dubois, G.G., Bardwell, J.C.A., and Court, D.L. (1990) Expression and characterization of RNase III and Era proteins. J Biol Chem 265: 2888-2895.
13. Court, D. (1993) RNA processing and degradation by RNase III. In Control of Messenger RNA stability. Belasco, J., and Brawerman, G. (eds). San Diego, CA: Academic Press, pp. 71-116.
14. Donachie, W.D., and Begg, K.J. (1989) Chromosome partition in Escherichia coli requires post-replication protein synthesis. J Bacteriol 171: 5405-5409.
15. Dong, H., Kirsebom, L.A., and Nilsson, L. (1996) Growth rate regulation of 4.5S RNA and M1 RNA the catalytic subunit of Escherichia coli RNase P. J Mol Biol 261: 303-308.
16. Dunn, J.J. (1976) RNase III cleavage of single-stranded RNA. Effect of ionic strength on the fidelity of cleavage. J Biol Chem 251: 3807-3814.
17. Elledge, S.J. (1997) Cell cycle checkpoints: preventing an identity crisis. Science 274: 1664-1672.
18. Erickson, H.P., Taylor, D.W., Taylor, K.A., and Bramhill, D. (1996) Bacterial cell division protein FtsZ assembles into protofilament sheets and minirings, structural homologs of tubulin polymers. Proc Natl Acad Sci USA 93: 519-523.
19. Gollop, N., and March, P.E. (1991) A GTP-binding protein (Era) has an essential role in growth rate and cell cycle control in Escherichia coli. J Bacteriol 173: 2265-2270.
20. Grompe, M., Versalovic, J., Koeuth, T., and Lupski, J.R. (1991) Mutations in the Escherichia coli dnaG gene suggest coupling between DNA replication and chromosome partitioning. J Bacteriol 173: 1268-1278.
21. Hale, C.A., and de Boer, P.A. (1997) Direct binding of FtsZ to ZipA, an essential component of the septal ring structure that mediates cell division in E. coli. Cell 88: 175-185.
22. Hiraga, S., Niki, H., Ogura, T., Ichinose, C., Mori, H., Ezaki, B., et al. (1989) Chromosome partitioning in Escherichia coli: novel mutants producing anucleate cells. J Bacteriol 171: 1496-1505.
23. Hiraga, S., Ogura, T., Ichinose, C., and Mori, H. (1990) Positioning of replicated chromosomes in Escherichia coli. J Bacteriol 172: 31-39.
24. Hirota, Y., Ryter, A., and Jacob, F. (1968) Thermosensitive mutants of E. coli affected in the processes of DNA synthesis and cellular division. Cold Spring Harb Symp Quant Biol 33: 677-693.
25. Hirota, Y., Ricard, M., and Shapiro, B. (1971) The use of thermosensitive mutants of E. coli in the analysis of cell division. Biomembranes 2: 13-31.
26. Holland, I.B. (1987) Genetic analysis of the E. coli division clock. Cell 48: 361-362.
27. Inada, T., Kawakami, K., Chen, S.-M., Takiff, H., Court, D., and Nakamura, Y. (1989) Temperature-sensitive lethal mutant of Era, a G protein in Escherichia coli. J Bacteriol 171: 5017-5024.
28. Lerner, C.G., and Inouye, M. (1991) Pleiotropic changes resulting from depletion of Era, an essential GTP-binding protein in Escherichia coli. Mol Microbiol 5: 951-957.
29. Levin, P.A., and Losick, R. (1996) Transcription factor SpoOA switches the localization of the cell division protein FtsZ from a medial to a bipolar pattern in Bacillus subtilis. Genes Dev 10: 478-488.
30. Lin, Y.P., Sharer, J.D., and March, P.E. (1994) GTPase-dependent signaling in bacteria: characterization of a membrane-binding site for era in Escherichia coli. J Bacteriol 176: 44-49.
31. Ma, X., Ehrhardt, D.W., and Margolin, W. (1996) Co-localization of cell division proteins FtsZ and FtsA to cytoskeletal structures in living Escherichia coli cells by using green fluorescent protein. Proc Natl Acad Sci USA 93: 12998-13003.
32. Marshall, C. (1985) Human oncogenes. In RNA Tumor Viruses. Weiss, R., Teich, N., Varmus, H., and Coffin, J. (eds). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, pp. 487-558.
33. Matsunaga, J., Dyer, M., Simons, E.L., and Simons, R.W. (1996) Expression and regulation of the rnc and pdxJ operons of Escherichia coli. Mol Microbiol 22: 977-989.
34. Miller, J.H. (1972) Experiments in Molecular Genetics. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
35. Morishita, T., Mitsuzawa, H., Nakafuku, M., Nakamura, S., Hattori, S., and Anraku, Y. (1995) Requirement of Saccharomyces cerevisiae Ras for completion of mitosis. Science 270: 1213-1215.
36. Mukherjee, A., and Lutkenhaus, J. (1994) Guanine nucleotide-dependent assembly of FtsZ into filaments. J Bacteriol 176: 2754-2758.
37. Nashimoto, H. (1993) Non-ribosomal proteins affecting the assembly of ribosomes in Escherichia coli. In The Translation Apparatus. Nierhaus, K.H., Franceschi, F., Subramanian, A.R., Erdmann, V.A., and Wittmann-Liebold, B. (eds). New York: Plenum Press, pp. 185-195.
38. Niki, H., Jaffe, A., Imamura, R., Ogura, T., and Hiraga, S. (1991) The new gene mukB codes for a 177kDa protein with coiled coil domains involved in chromosome partitioning in E. coli. EMBO J 10: 183-193.
39. Pillutla, R.C., Sharer, J.D., Gulati, P.S., Wu, E., Yamashita, Y., Lerner, C.G., et al. (1995) Cross-species complementation of the indispensable Escherichia coli era gene high-lights amino acid regions essential for activity. J Bacteriol 177: 2194-2196.
40. Powell, B.S., Court, D.L., Inada, T., Nakamura, Y., Michotey, V., Cui, X., et al. (1995) Novel proteins of the phosphotransferase system encoded within the rpoN operon of Escherichia coli. J Biol Chem 270: 4822-4839.
41. Powell, B.S., Rivas, M.P., Court, D.L., Nakamura, Y., and Turnbough, Jr, C.L. (1994) Rapid confirmation of single copy lambda prophage integration by PCR. Nucleic Acids Res 22: 5765-5766.
42. Sood, P., Lerner, C.G., Shimamoto, T., Lu, Q., and Inouye, M. (1994) Characterization of the autophosphorylation of Era, an essential GTPase in Escherichia coli. Mol Microbiol 12: 201-208.
43. Takiff, H., Chen, S.-M., and Court, D.L. (1989) Genetic analysis of the rnc operon of Escherichia coli. J Bacteriol 171: 2581-2590.
44. Takiff, H.E., Baker, T., Copeland, T., Chen, S.-M., and Court, D.L. (1992) Locating essential Escherichia coli genes by using mini-Tn10 transposons: the pdxJ operon. J Bacteriol 174: 1544-1553.
45. van Helvoort, J.M.L.M., and Woldringh, C.L. (1994) Nucleoid partitioning in Escherichia coli during steady-state growth and upon recovery from chloramphenicol treatment. Mol Microbol 13: 577-583.
46. Zuber, M., Hoover, T.A., Dertzbaugh, M.T., and Court, D.L. (1997) A Francisella tularensis DNA clone complements Escherichia coli defective for the production of Era, an essential Ras-like GTP-binding protein. Gene 189: 31-34.