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Volumn 9, Issue 1, 1998, Pages 59-68

From rodents to recovery: Development of animal models of schizophrenia

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; COGNITION; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; HIPPOCAMPUS; LATENT INHIBITION; LIGAND BINDING; NEUROLOGIC DISEASE; NEUROTRANSMITTER RELEASE; NONHUMAN; PREPULSE INHIBITION; PRIORITY JOURNAL; RAT; REVIEW; SCHIZOPHRENIA; SOCIAL ISOLATION; SYMPTOMATOLOGY;

EID: 0031952598     PISSN: 11727047     EISSN: None     Source Type: Journal    
DOI: 10.2165/00023210-199809010-00006     Document Type: Review
Times cited : (4)

References (49)
  • 1
    • 0021348560 scopus 로고
    • The validity of animal models of depression
    • Willner P. The validity of animal models of depression. Psychopharmacology 1984; 83: 1-16
    • (1984) Psychopharmacology , vol.83 , pp. 1-16
    • Willner, P.1
  • 2
    • 0019054016 scopus 로고
    • Brain dopamine receptors
    • Seeman P. Brain dopamine receptors. Pharmacol Review 1980; 32: 229-313
    • (1980) Pharmacol Review , vol.32 , pp. 229-313
    • Seeman, P.1
  • 3
    • 0017277759 scopus 로고
    • The dopamine hypothesis of schizophrenia: Focus on the dopamine receptor
    • Snyder SH. The dopamine hypothesis of schizophrenia: focus on the dopamine receptor. Am J Psychiatry 1976; 133: 197-202
    • (1976) Am J Psychiatry , vol.133 , pp. 197-202
    • Snyder, S.H.1
  • 4
    • 0142216698 scopus 로고
    • Animal models: Promises and problems
    • Hanin I. Usdin E. editors. New York: Pergamon Press
    • Kornetsky C. Animal models: promises and problems. In: Hanin I. Usdin E. editors. Animal models in psychiatry and neurology. New York: Pergamon Press, 1977: 1-7
    • (1977) Animal Models in Psychiatry and Neurology , pp. 1-7
    • Kornetsky, C.1
  • 5
    • 0018144051 scopus 로고
    • Classification of neuroleptic drugs according to their ability to inhibit apomorphine-induced locomotion and gnawing: Evidence for two different mechanisms of action
    • Ljunberg T, Ungerstedt U. Classification of neuroleptic drugs according to their ability to inhibit apomorphine-induced locomotion and gnawing: evidence for two different mechanisms of action. Psychopharmacology 1978; 56: 239-47
    • (1978) Psychopharmacology , vol.56 , pp. 239-247
    • Ljunberg, T.1    Ungerstedt, U.2
  • 6
    • 0026091799 scopus 로고
    • The mechanism of action of novel antipsychotic drugs
    • Meltzer HY. The mechanism of action of novel antipsychotic drugs. Schizophr Bull 1991; 17: 263-87
    • (1991) Schizophr Bull , vol.17 , pp. 263-287
    • Meltzer, H.Y.1
  • 7
    • 0028943726 scopus 로고
    • Pre-clinical pharmacology of new atypical antipsychotics in late stage development
    • Goldstein JM. Pre-clinical pharmacology of new atypical antipsychotics in late stage development. Exp Opin Invest Drugs 1995; 4: 291-8
    • (1995) Exp Opin Invest Drugs , vol.4 , pp. 291-298
    • Goldstein, J.M.1
  • 9
    • 0031016120 scopus 로고    scopus 로고
    • Olanzapine: A review of its pharmacological properties and therapeutic efficacy in the management of schizophrenia and related psychoses
    • Fulton B, Goa KL. Olanzapine: a review of its pharmacological properties and therapeutic efficacy in the management of schizophrenia and related psychoses. Drugs 1997; 53: 281-98
    • (1997) Drugs , vol.53 , pp. 281-298
    • Fulton, B.1    Goa, K.L.2
  • 10
    • 0004038456 scopus 로고
    • New York: International University Press
    • Bleuler E. Dementia praecox. New York: International University Press, 1950
    • (1950) Dementia Praecox
    • Bleuler, E.1
  • 12
    • 0028371468 scopus 로고
    • Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients
    • Swerdlow NR, Braff DL, Taaid N, et al. Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients. Arch Gen Psychiatry 1994; 51: 139-54
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 139-154
    • Swerdlow, N.R.1    Braff, D.L.2    Taaid, N.3
  • 13
    • 0027101872 scopus 로고
    • From an animal model of an attentional deficit towards new insights into the pathophysiology of schizophrenia
    • Feldon J, Weiner I. From an animal model of an attentional deficit towards new insights into the pathophysiology of schizophrenia. J Psychiatr Res 1992; 26: 345-66
    • (1992) J Psychiatr Res , vol.26 , pp. 345-366
    • Feldon, J.1    Weiner, I.2
  • 15
    • 0021088528 scopus 로고
    • Stereotyped responding by schizophrenic-patients on a two-choice guessing task
    • Frith CD, Done DJ. Stereotyped responding by schizophrenic-patients on a two-choice guessing task. Psychol Med 1983; 13: 779-86
    • (1983) Psychol Med , vol.13 , pp. 779-786
    • Frith, C.D.1    Done, D.J.2
  • 16
    • 0014174023 scopus 로고
    • Stereotyped activity in several species animal species including man
    • Randrup A, Munkvad I. Stereotyped activity in several species animal species including man. Psychopharmacologia 1967; 11: 300-10
    • (1967) Psychopharmacologia , vol.11 , pp. 300-310
    • Randrup, A.1    Munkvad, I.2
  • 17
    • 0020581260 scopus 로고
    • Increased response switching, perseveration and perseverative switching following d-amphetamine in the rat
    • Evenden JL, Robbins TW. Increased response switching, perseveration and perseverative switching following d-amphetamine in the rat. Psychopharmacology 1983; 80: 67-73
    • (1983) Psychopharmacology , vol.80 , pp. 67-73
    • Evenden, J.L.1    Robbins, T.W.2
  • 18
    • 0023690886 scopus 로고
    • Stereotyped responding on a two-choice guessing task by marmosets and humans treated with amphetamine
    • Ridley RM, Baker HF, Frith CD, et al. Stereotyped responding on a two-choice guessing task by marmosets and humans treated with amphetamine. Psychopharmacology 1988; 95: 560-4
    • (1988) Psychopharmacology , vol.95 , pp. 560-564
    • Ridley, R.M.1    Baker, H.F.2    Frith, C.D.3
  • 19
    • 0000683636 scopus 로고
    • Animal models with construct validity for schizophrenia
    • Ellenbroek BA, Cools AR. Animal models with construct validity for schizophrenia. Behav Pharmacol 1990; 1: 469-90
    • (1990) Behav Pharmacol , vol.1 , pp. 469-490
    • Ellenbroek, B.A.1    Cools, A.R.2
  • 20
    • 0025829428 scopus 로고
    • Prepulse inhibition as a screening test for potential antipsychotics
    • Rigdon GC, Viik K. Prepulse inhibition as a screening test for potential antipsychotics. Drug Dev Res 1991; 23: 91-9
    • (1991) Drug Dev Res , vol.23 , pp. 91-99
    • Rigdon, G.C.1    Viik, K.2
  • 21
    • 0028828716 scopus 로고
    • Examination of drug-induced and isolation-induced disruptions of prepulse inhibition as models to screen antipsychotic drugs
    • Varty GB, Higgins GA. Examination of drug-induced and isolation-induced disruptions of prepulse inhibition as models to screen antipsychotic drugs. Psychopharmacology 1995; 122: 15-26
    • (1995) Psychopharmacology , vol.122 , pp. 15-26
    • Varty, G.B.1    Higgins, G.A.2
  • 22
    • 0028834467 scopus 로고
    • Reversal of a dizocilpine-induced disruption of prepulse inhibition of an acoustic startle response by the 5-HT2 receptor antagonist ketanserin
    • Varty GB, Higgins GA. Reversal of a dizocilpine-induced disruption of prepulse inhibition of an acoustic startle response by the 5-HT2 receptor antagonist ketanserin. Eur J Pharmacol 1995; 287: 201-5
    • (1995) Eur J Pharmacol , vol.287 , pp. 201-205
    • Varty, G.B.1    Higgins, G.A.2
  • 23
    • 0018626107 scopus 로고
    • Lateral cerebral ventricular enlargement in chronic schizophrenia
    • Weinberger DR, Torrey EF, Neophytides A, et al. Lateral cerebral ventricular enlargement in chronic schizophrenia. Arch Gen Psychiatry 1979; 36: 735-8
    • (1979) Arch Gen Psychiatry , vol.36 , pp. 735-738
    • Weinberger, D.R.1    Torrey, E.F.2    Neophytides, A.3
  • 24
    • 0025327621 scopus 로고
    • Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia
    • Suddath RL, Christison GW, Torrey EF, et al. Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia. N Engl J Med 1990; 322: 789-94
    • (1990) N Engl J Med , vol.322 , pp. 789-794
    • Suddath, R.L.1    Christison, G.W.2    Torrey, E.F.3
  • 25
    • 0029119055 scopus 로고
    • Schizophrenia: From neuropathology to neurodevelopment
    • Weinberger DR. Schizophrenia: from neuropathology to neurodevelopment. Lancet 1995; 346: 552-7
    • (1995) Lancet , vol.346 , pp. 552-557
    • Weinberger, D.R.1
  • 26
    • 0025316314 scopus 로고
    • Schizophrenia: The cellular biology of a functional psychosis
    • Roberts GW. Schizophrenia: the cellular biology of a functional psychosis. Trends Neurosci 1990; 13: 207-11
    • (1990) Trends Neurosci , vol.13 , pp. 207-211
    • Roberts, G.W.1
  • 27
    • 0023785808 scopus 로고
    • Specification of cerebral cortical areas
    • Rakic P. Specification of cerebral cortical areas. Science 1988; 241: 170-6
    • (1988) Science , vol.241 , pp. 170-176
    • Rakic, P.1
  • 28
    • 0021251731 scopus 로고
    • Dual pathways connecting the dorsolateral prefrontal cortex with the hippocampal formation and parahippocampal cortex in rhesus monkey
    • Goldman-Rakic PS, Selemon LD, Schwartz ML. Dual pathways connecting the dorsolateral prefrontal cortex with the hippocampal formation and parahippocampal cortex in rhesus monkey. Neuroscience 1984; 12: 719-43
    • (1984) Neuroscience , vol.12 , pp. 719-743
    • Goldman-Rakic, P.S.1    Selemon, L.D.2    Schwartz, M.L.3
  • 29
    • 0026452427 scopus 로고
    • Negative symptoms and hypofrontality in chronic schizophrenia
    • Wolkin A, Sanfilipo M, Wolfi AP, et al. Negative symptoms and hypofrontality in chronic schizophrenia. Arch Gen Psychiatry 1992; 49: 959-65
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 959-965
    • Wolkin, A.1    Sanfilipo, M.2    Wolfi, A.P.3
  • 30
    • 0019190758 scopus 로고
    • Effect of lesion of cortical dopamine terminals on subcortical dopamine receptors in the rat
    • Pycock CJ, Kerwin RW, Carter CJ. Effect of lesion of cortical dopamine terminals on subcortical dopamine receptors in the rat. Nature 1980; 286: 74-7
    • (1980) Nature , vol.286 , pp. 74-77
    • Pycock, C.J.1    Kerwin, R.W.2    Carter, C.J.3
  • 31
    • 0026738711 scopus 로고
    • Ibotenic acid lesion of the ventral hippocampus differentially affects dopamine and its metabolites in the nucleus accumbens and prefrontal cortex in the rat
    • Lipska BK, Jaskiw GE, Chrapusta S, et al. Ibotenic acid lesion of the ventral hippocampus differentially affects dopamine and its metabolites in the nucleus accumbens and prefrontal cortex in the rat. Brain Res 1992; 585: 1-6
    • (1992) Brain Res , vol.585 , pp. 1-6
    • Lipska, B.K.1    Jaskiw, G.E.2    Chrapusta, S.3
  • 32
    • 0028886663 scopus 로고
    • Neonatal excitotoxic hippocampal damage in rats causes post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine
    • Lipska BK, Swerdlow NR, Geyer MA, et al. Neonatal excitotoxic hippocampal damage in rats causes post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine. Psychopharmacology 1995; 122: 35-43
    • (1995) Psychopharmacology , vol.122 , pp. 35-43
    • Lipska, B.K.1    Swerdlow, N.R.2    Geyer, M.A.3
  • 33
    • 0002254125 scopus 로고
    • Animal models of schizophrenia
    • Lipton MA, DiMascio A, Killam KF, editors. New York: Raven Press
    • Kornetsky C, Markowitz A. Animal models of schizophrenia. In: Lipton MA, DiMascio A, Killam KF, editors. Psychopharmacology: a generation of progress. New York: Raven Press, 1978: 583-93
    • (1978) Psychopharmacology: A Generation of Progress , pp. 583-593
    • Kornetsky, C.1    Markowitz, A.2
  • 34
    • 0026671676 scopus 로고
    • Dopaminergic and serotonergic function following isolation rearing in rats: Study of behavioural responses and postmortem and in vivo neurochemistry
    • Jones GH, Hernandez TD, Kendall DA, et al. Dopaminergic and serotonergic function following isolation rearing in rats: study of behavioural responses and postmortem and in vivo neurochemistry. Pharmacol Biochem Behav 1992; 43: 17-35
    • (1992) Pharmacol Biochem Behav , vol.43 , pp. 17-35
    • Jones, G.H.1    Hernandez, T.D.2    Kendall, D.A.3
  • 35
    • 0016427881 scopus 로고
    • The effects of psychomotor stimulants on locomotor activity and stereotypy in socially deprived and control rats
    • Sahakian BJ, Robbins TW, Iversen SD. The effects of psychomotor stimulants on locomotor activity and stereotypy in socially deprived and control rats. Brain Res 1975; 84: 195-205
    • (1975) Brain Res , vol.84 , pp. 195-205
    • Sahakian, B.J.1    Robbins, T.W.2    Iversen, S.D.3
  • 36
    • 0025861675 scopus 로고
    • Effect of isolation on 5-HT agonist-induced responses in the rat
    • Wright IK, Ismail H, Upton N, et al. Effect of isolation on 5-HT agonist-induced responses in the rat. Psychopharmacology 1991; 105: 259-63
    • (1991) Psychopharmacology , vol.105 , pp. 259-263
    • Wright, I.K.1    Ismail, H.2    Upton, N.3
  • 37
    • 0001102609 scopus 로고
    • The effects of isolation rearing on behavioural inhibition in the rat
    • Morgan MJ, Einon DF, Nicholas D. The effects of isolation rearing on behavioural inhibition in the rat. Q J Exp Psychol 1975; 27: 615-34
    • (1975) Q J Exp Psychol , vol.27 , pp. 615-634
    • Morgan, M.J.1    Einon, D.F.2    Nicholas, D.3
  • 38
    • 0027515470 scopus 로고
    • Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia
    • Geyer MA, Wilkinson LS, Humby T, et al. Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia. Biol Psychiatry 1993; 34: 361-72
    • (1993) Biol Psychiatry , vol.34 , pp. 361-372
    • Geyer, M.A.1    Wilkinson, L.S.2    Humby, T.3
  • 39
    • 0027296447 scopus 로고
    • m-Chlorophenylpiperazine effects in neuroleptic-free schizophrenic patients
    • Krystal JH, Seibyl JP, Price LH, et al. m-Chlorophenylpiperazine effects in neuroleptic-free schizophrenic patients. Arch Gen Psychiatry 1993; 50: 624-35
    • (1993) Arch Gen Psychiatry , vol.50 , pp. 624-635
    • Krystal, J.H.1    Seibyl, J.P.2    Price, L.H.3
  • 40
    • 15144347892 scopus 로고    scopus 로고
    • Reduced synaptophysin immunoreactivity in the hippocampus of PPI-deficient, isolation reared rats
    • Varty GB, Higgins GA. Reduced synaptophysin immunoreactivity in the hippocampus of PPI-deficient, isolation reared rats. J Psychopharmacology 1996; 10 Suppl.: A24
    • (1996) J Psychopharmacology , vol.10 , Issue.SUPPL.
    • Varty, G.B.1    Higgins, G.A.2
  • 41
    • 0028853825 scopus 로고
    • Decreased synaptophysin in the medial temporal lobe in schizophrenia demonstrated using immunoautodiography
    • Eastwood SL, Harrison PJ. Decreased synaptophysin in the medial temporal lobe in schizophrenia demonstrated using immunoautodiography. Neuroscience 1995; 69: 339-43
    • (1995) Neuroscience , vol.69 , pp. 339-343
    • Eastwood, S.L.1    Harrison, P.J.2
  • 42
    • 0030848168 scopus 로고    scopus 로고
    • Schizophrenia and L-745870, a novel dopamine D4 receptor antagonist
    • Bristow LJ, Kramer MS, Kulagowski J, et al. Schizophrenia and L-745870, a novel dopamine D4 receptor antagonist. Trends Neurosci 1997; 18: 186-8
    • (1997) Trends Neurosci , vol.18 , pp. 186-188
    • Bristow, L.J.1    Kramer, M.S.2    Kulagowski, J.3
  • 43
    • 0026581360 scopus 로고
    • Gating and habituation of the startle reflex in schizophrenic patients
    • Braff DL, Grillon C, Geyer MA. Gating and habituation of the startle reflex in schizophrenic patients. Arch Gen Psychiatry 1992; 49: 206-15
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 206-215
    • Braff, D.L.1    Grillon, C.2    Geyer, M.A.3
  • 45
    • 0030451234 scopus 로고    scopus 로고
    • Molecular genetics of schizophrenia
    • ODonovan MC, Owen MJ. Molecular genetics of schizophrenia. Ann Med 1996; 28: 541-6
    • (1996) Ann Med , vol.28 , pp. 541-546
    • Odonovan, M.C.1    Owen, M.J.2
  • 46
    • 0029873266 scopus 로고    scopus 로고
    • Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene
    • Williams J, Spurlock G, McGuffin P, et al. Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene. Lancet 1996; 347: 1294-6
    • (1996) Lancet , vol.347 , pp. 1294-1296
    • Williams, J.1    Spurlock, G.2    McGuffin, P.3
  • 47
    • 0029876529 scopus 로고    scopus 로고
    • Schizophrenia, the heteromodal association neocortex and development: Potential for a neurogenic approach
    • Ross CA, Pearlson GD. Schizophrenia, the heteromodal association neocortex and development: potential for a neurogenic approach. Trends Neurosci 1996; 19: 171-6
    • (1996) Trends Neurosci , vol.19 , pp. 171-176
    • Ross, C.A.1    Pearlson, G.D.2
  • 48
    • 0030866899 scopus 로고    scopus 로고
    • Social interaction and sensorimotor gating abnormalities in mice lacking Dv11
    • Lijam N, Paylor R, McDonald MP, et al. Social interaction and sensorimotor gating abnormalities in mice lacking Dv11. Cell 1997; 90: 895-905
    • (1997) Cell , vol.90 , pp. 895-905
    • Lijam, N.1    Paylor, R.2    McDonald, M.P.3
  • 49
    • 0030750286 scopus 로고    scopus 로고
    • Inbred strain differences in prepulse inhibition of the mouse startle response
    • Paylor R, Crawley J. Inbred strain differences in prepulse inhibition of the mouse startle response. Psychopharmacology 1997; 132: 169-80
    • (1997) Psychopharmacology , vol.132 , pp. 169-180
    • Paylor, R.1    Crawley, J.2


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