Preclinical assessment of immunoreactivity of a new purified equine F(ab′)2 against European viper venom

Journal of Pharmaceutical Sciences

Volumn 87, Issue 2, 1998, Pages 221-225

  Pepin Covatta, Stephanie ^a   Lutsch, Charles ^b   Lang, Jean ^b   Scherrmann, Jean Michel ^a,c  

^a HÔPITAL FERNAND WIDAL   (France)

^b Pasteur Merieux Connaught (PMC)   (France)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN F(AB')2 FRAGMENT; IPSER; UNCLASSIFIED DRUG; VENOM ANTISERUM; VIPER VENOM; VIPERFAV;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN ANTIBODY COMPLEX; AREA UNDER THE CURVE; ARTICLE; BIOSENSOR; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFICACY; DRUG POTENCY; DRUG PURIFICATION; DRUG SCREENING; ENVENOMATION; HORSE; INTRAVENOUS DRUG ADMINISTRATION; LD 50; MALE; MOUSE; NONHUMAN; PASTEURIZATION; RABBIT; SNAKEBITE; STOICHIOMETRY;

EID: 0031952448     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js9701824     Document Type: Article

References (30)

1. Sutherland, S. K. Serum reactions. An analysis of commercial antivenoms and the possible role of anticomplementary activity in de-novo reactions to antivenoms and antitoxins. Med. J. Aust. 1977, 1, 613-615.
2. Sullivan, J. B. Past, Present, and Future Immunotherapy of Snake Venom Poisoning. Ann. Emerg. Med. 1987, 16, 938-944.
3. Smith, T. W.; Haber, E.; Yeatman, L.; Butler, V. P. Reversal of advanced digoxin intoxication with Fab fragments of digoxin-specific antibodies. N. Eng. J. Med. 1976, 294, 797-800.
4. Hickey, A. R.; Wenger, T. L.; Carpenter, V. P. Digoxin Immune Fab therapy in the management of digitalis intoxication: Safety and efficacy results of an observational surveillance study. J. Am. Coll. Cardiol. 1991, 17, 590-598.
5. 2 antivenoms: An example: New polyvalent anti-European vipers (equine). In Envenomings and their treatments; Bon, C., Goyffon, M., Eds.; Fond. Marcel: Merieux, Lyon, 1996; pp 161-172.
6. 2-scorpion venom interactions. Toxicol. Appl. Pharmacol. 1996, 141, 272-277.
7. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970, 227, 680-685.
8. Karlsson, R.; Michaelsson, A.; Mattsson, L. Kinetic analysis of monoclonal antibody-antigen interactions with a new biosensor based analytical system. J. Immunol. Methods. 1991, 145, 229-240.
9. Kretschmann, E.; Raether, H. Radiative decay of nonradiative surface plasmons excited by light. Z. Naturforsch. A. 1968, 23, 2135-2136.
10. Liedberg, B.; Nylander, C.; Lundström, I. Surface plasmon resonance for gas detection and biosensing. Sens. Actua. 1983, 4, 299-304.
11. Fägerstam, L G.; Frostell, A.; Karlsson, R. Detection of antigen-antibody interactions by surface plasmon resonance. J. Mol. Recognit. 1990, 3, 208-214.
12. Löfas, S.; Johnsson, B. A novel hydrogel matrix on gold surfaces in surface plasmon resonance sensors for fast and efficient covalent immobilisation of ligands. J. Chem. Soc. Chem. Commun. 1990, 1526-1528.
13. Johnsson, B. S.; Löfas, S.; Lindqvist, G. Comparison of methods for immobilisation to carboxymethyl dextran sensor surfaces by analysis of the specific activity of monoclonal antibodies. Anal. Biochem. 1991, 198, 268-277.
14. Fägerstam, L G.; Frostell-Karlsson, A.; Karlsson, R.; Persson, B.; Rönnberg, I. Biospecific interaction analysis using surface plasmon resonance detection applied to kinetic, binding site and concentration analysis. J. Chromatograph. 1991, 597, 397-410.
15. Fraker, P. J.; Speck, J. C. Protein and cell membrane iodinations with a sparingly soluble chloroamide 1,3,4,6-tetrachloro-3α-6α-diphenylglycoluril. Biochem. Biophys. Res. Commun. 1978, 80, 849-857.
16. Gibaldi, M.; Perrier, D. In Pharmacokinetics; Gibaldi, M., Perrier, D., Eds.; Marcel Dekker Inc.: New York, 1982; pp 199-219.
17. Chippaux, J. P.; Goyffon, M. Bull. Soc. Path. Ex., 1991, 84, 286-297.
18. Scherrmann, J. M.; Terrien, N.; Urtizberea, M.; Pierson, P.; Denis, H.; Bourre, J. M. Immunotoxicotherapy: Present status and future trends. J. Toxicol. Clin. Toxicol. 1989, 27, 1-35.
19. Butler, V. P.; Schmidt, D. H.; Smith, T. W. Effects of sheep digoxin-specific antibodies and their Fab fragments on digoxin pharmacokinetics in dogs. J. Clin. Invest. 1977, 59, 345-359.
20. Pentel, P.; Pond, S. M.; Schoof, D. Redistribution into plasma of tracer doses of desipramine by anti-desipramine antiserum in rats. Biochem. Pharmacol. 1987, 36, 293-295.
21. Sabouraud, A.; Urtizberea, M.; Cano, N.; Grandgeorge, M.; Rouzioux, J. M.; Scherrmann, J. M. Colchicine-specific Fab fragments alter colchicine disposition in rabbits. J. Pharmacol. Exp. Ther. 1992, 260, 1214-1219.
22. Pentel, P. R.; Keyler, D. E.; Brunn, G. J. Redistribution of tricyclic antidepressants in rats using a drug-specific monoclonal antibody: Dose-response relationship. Drug Metab. Dispos. 1991, 19, 24-28.
23. Sullivan, J. B. Immunotherapy in the poisoned patient. Overview of present applications and future trends. Med. Toxicol. 1986, 1, 47-60.
24. Dos Santos, M. C.; D'Imperio Lima, M. R.; Furtado, G. C.; Colletto, G. M. D. D.; Kipnis, T. L.; Dias Da Silva, W. Purification of F(ab′)2 anti-snake venom by caprylic acid: a fast method for obtaining IgG fragments with high neutralization activity, purify and yield. Toxicon 1989, 27, 297-303.
25. Carroll, S.; Thalley, B.; Theakston, D.; Laing, G. Comparison of purity and efficacy of affinity purified antivenoms with commercial equine crotalid antivenoms. Toxicon 1992, 30, 1017-1025.
26. Sjostrom, L.; Al-Abdulla, I. H.; Rawat, S.; Smith, D. C.; Landon, J. A comparison of ovine and equine antivenoms. Toxicon 1994, 32, 427-433.
27. T from hyperimmune horse anti-snake venom serum: its protective ability. Toxicon 1991, 29, 1373-1379.
28. 2 antivenom from hyperimmunized horse: pharmacokinetics following intravenous and intramuscular administrations in rabbits. Pharm. Res. 1995, 12 (10), 1470-1473.
29. Audebert, F.; Urtizberea, M.; Sabouraud, A.; Scherrmann, J. M.; Bon, C. Pharmacokinetics of Vipera aspis venom after experimental envenomation in rabbits. J. Pharmacol. Exp. Ther. 1994, 268, 1512-1517.
30. Johnston, P., Stevenson, I., Hewick, D. The influence of digoxin-specific antibody fragments on digoxin disposition in the rat. Biochem. Pharmacol. 1987, 36, 2215-2220.