Plasma extravasation through neuronal stimulation in human nasal mucosa in the setting of allergic rhinitis

Journal of Applied Physiology

Volumn 84, Issue 2, 1998, Pages 537-543

  Sanico, Alvin M ^a,b   Atsuta, Satsuki ^a   Proud, David ^a   Togias, Alkis ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

Capsaicin; Neurogenic inflammation

Indexed keywords

ALBUMIN; ATROPINE; BRADYKININ; CAPSAICIN; FIBRINOGEN; LIDOCAINE; LYSOZYME; PLACEBO;

ADULT; AGED; ALLERGIC RHINITIS; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EXTRAVASATION; FEMALE; HUMAN; HUMAN TISSUE; MALE; NERVE STIMULATION; NEUROGENIC INFLAMMATION; NOSE MUCOSA; NOSE MUCUS; NOSE PROVOCATION TEST; PRIORITY JOURNAL; SENSORY NERVE;

EID: 0031952422     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1998.84.2.537     Document Type: Article

References (41)

1. Asakura, K., H. Shirasaki, S. Narita, T. Kojima, and A. Kataura. Study on the dye leakage response of nasal mucosa following topical, capsaicin challenge in guinea pigs. Acta Otolaryngol. 112: 545-551, 1992.
2. Baraniuk, J. N., J. D. Lundgren, H. Mizoguchi, D. Peden, A. Gawin, M. Merida, J. H. Shelhamer, and M. Kaliner. Bradykinin and respiratory mucous membranes: analysis of bradykinin binding site distribution and secretory responses in vitro and in vivo. Am. Rev. Respir. Dis. 141: 706-714, 1990.
3. Baraniuk, J. N., P. B. Silver, M. A. Kaliner, and P. J. Barnes. Perennial rhinitis subjects have altered vascular, glandular, and neural responses to bradykinin nasal provocation. Int. Arch. Allergy Immunol. 103: 202-208, 1994.
4. Barnes, P. J. Neurogenic inflammation in airways. Int. Arch. Allergy Appl. Immunol. 94: 303-309, 1991.
5. Bascom, R., A. Kagey-Sobotka, and D. Proud. Effect of intranasal capsaicin on symptoms and mediator release. J. Pharmacol. Exp. Ther. 259: 1323-1327, 1991.
6. Berman, A. R., M. C. Liu, E. M. Wagner, and D. Proud. Dissociation of bradykinin-induced plasma exudation and reactivity in the peripheral airways. Am. J. Respir. Crit. Care Med. 154: 418-423, 1996.
7. Brokaw, J. J., C. M. Hillenbrand, G. W. White, and D. M. McDonald. Mechanism of tachyphylaxis associated with neurogenic plasma extravasation in the rat trachea. Am. Rev. Respir. Dis. 141: 1434-1440, 1990.
8. Budavari, S., M. J. O'Neil, A. Smith, and P. E. Heckelman. The Merck Index (11th ed.). Rahway, NJ: Merck & Co., Inc., 1989.
9. Churchill, L., J. A. Pongracic, C. J. Reynolds, R. M. Naclerio, and D. Proud. Pharmacology of nasal provocation with bradykinin: studies of tachyphylaxis, cyclooxygenase inhibition, alpha-adrenergic stimulation, and receptor subtype. Int. Arch. Allergy Appl. Immunol. 95: 322-331, 1991.
10. Erjefalt, I., and C. G. A. Persson. Anti-asthma drugs and capsaicin-induced microvascular effects in lower airways. Agents Actions 16: 9-10, 1985.
11. Erjefalt, I., and C. G. A. Persson. Pharmacologic control of plasma exudation into tracheobronchial airways. Am. Rev. Respir. Dis. 143: 1008-1014, 1991.
12. Geppetti, P., B. M. Fusco, S. Marabini, C. A. Maggi, M. Fanciullacci, and F. Sicuteri. Secretion, pain and sneezing induced by the application of capsaicin to the nasal mucosa in man. Br. J. Pharmacol. 93: 509-514, 1988.
13. Greiff, L., C. Svensson, M. Andersson, and C. G. Persson. Effects of topical capsaicin in seasonal allergic rhinitis. Thorax 50: 225-229, 1995.
14. Hardman, J. G., L. E. Limbird, P. B. Molinoff, R. W. Ruddon, and A. G. Gilman. Goodman & Gilman's The Pharmacological Basis of Therapeutics (9th ed.). New York: McGraw-Hill, 1996.
15. Holzer, P. Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol. Rev. 43: 143-201, 1991.
16. Jancso, N., A. Jancso-Gabor, and J. Szolcsanyi. Direct evidence for neurogenic inflammation and its prevention by denervation and by pretreatment with capsaicin. Br. J. Pharmacol. Chemother. 31: 138-151, 1967.
17. Lundberg, J. M., and A. Saria. Capsaicin-sensitive vagal neurons involved in control of vascular permeability in rat trachea. Acta Physiol. Scand. 115: 521-523, 1982.
18. Lundberg, J. M., and A. Saria. Capsaicin-induced densensitization of airway mucosa to cigarette smoke, mechanical and chemical irritants. Nature 302: 251-253, 1983.
19. Lundblad, L., A. Saria, J. M. Lundberg, and A. Anggard. Increased vascular permeability in rat nasal mucosa induced by substance P and stimulation of capsaicin-sensitive trigeminal neurons. Acta Otolaryngol. 96: 479-484, 1983.
20. McDonald, D. M., R. A. Mitchell, G. Gabella, and A. Haskell. Neurogenic inflammation in the rat treachea. II. Identity and distribution of nerves mediating the increase in vascular permeability. J. Neurocytol. 17: 606-628, 1988.
21. Mizoguchi, H., and J. G. Widdicombe. Lateral nasal gland secretion in the anesthetized ferret. J. Appl. Physiol. 67: 2553-2555, 1989.
22. 1-receptor antagonist, RP 67580, inhibits neurogenic inflammation postsynaptically. Br. J. Pharmacol. 109: 259-264, 1993.
23. Mullol, J., G. D. Raphael, J. D. Lundgren, J. N. Baraniuk, M. Merida, J. H. Shelhamer, and M. A. Kaliner. Comparison of human nasal mucosal secretion in vivo and in vitro. J. Allergy Clin. Immunol. 89: 584-592, 1992.
24. Naclerio, R. M., H. L. Meier, A. Kagey-Sobotka, N. F. Adkinson, Jr., D. A. Meyers, P. S. Norman, and L. M. Lichtenstein. Mediator release after nasal airway challenge with allergen. Am. Rev. Respir. Dis. 128: 597-602, 1983.
25. Namimatsu, A., K. Go, H. Tanimoto, and M. Okuda. Mechanism of nasal secretion mediated via nerve reflex in guinea pigs and evaluation of antiallergic drugs. Int. Arch. Allergy Immunol. 97: 139-145, 1992.
26. Pernow, B. Role of tachykinins in neurogenic inflammation. J. Immunol. 135: 812-815, 1985.
27. Philip, G., F. M. Baroody, D. Proud, R. M. Naclerio, and A. G. Togias. The human nasal response to capsaicin. J. Allergy Clin. Immunol. 94: 1035-1045, 1994.
28. Philip, G., R. Jankowski, R. M. Naclerio, and A. Togias. Local anesthesia does not inhibit nasal glandular function (Abstract). Ann Allergy 70: 62, 1993.
29. Piedimonte, G., R. J. Pickles, J. R. Lehmann, D. McCarty, D. L. Costa, and R. C. Boucher. Replication-deficient adenoviral vector for gene transfer potentiates airway neurogenic inflammation. Am. J. Respir. Cell Mol. Biol. 16: 250-258, 1997.
30. Proud, D., C. J. Reynolds, S. LaCapra, A. Kagey-Sobotka, L. M. Lichtenstein, and R. M. Naclerio. Nasal provocation with bradykinin induces symptoms of rhinitis and a sore throat. Am. Rev. Respir. Dis. 137: 613-616, 1988.
31. Ramnarine, S. I., Y. Hirayama, P. J. Barnes, and D. F. Rogers. "Sensory-efferent" neural control of secretion: characterization using tachykinin receptor antagonists in ferret trachea in vitro. Br. J. Pharmacol. 113: 1183-1190, 1994.
32. Raphael, G. D., E. V. Jeney, J. N. Baraniuk, I. Kim, S. D. Meredith, and M. A. Kaliner. Pathophysiology of rhinitis: lactroferrin and lysozyme in nasal secretions. J. Clin. Invest. 84: 1528-1535, 1989.
33. Raphael, G. D., S. D. Meredith, J. N. Baraniuk, H. M. Druce, S. M. Banks, and M. A. Kaliner. The pathophysiology of rhinitis: II. Assessment of the sources of protein in histamine-induced nasal secretions. Am. Rev. Respir. Dis. 139: 791-800, 1989.
34. Reynolds, C. J., K. Porter, and D. Proud. Repeated intranasal administration of bradykinin to allergic individuals leads to tachyphylalxis (Abstract). J. Allergy Clin. Immunol. 99: S419, 1997.
35. Riccio, M. M., and D. Proud. Evidence that enhanced nasal reactivity to bradykinin in patients with symptomatic allergy is mediated by neural reflexes. J. Allergy Clin. Immunol. 97: 1252-1263, 1996.
36. Riccio, M. M., C. J. Reynolds, D. W. Hay, and D. Proud. Effects of intranasal administration of endothelin-1 to allergic and nonallergic individuals. Am. J. Respir. Crit. Care Med. 152: 1757-1764, 1995.
37. Sanico, A. M., S. Atsuta, D. Proud, and A. Togias. Dose dependent effects of capsaicin nasal challenge: in vivo evidence of human airway neurogenic inflammation. J. Allergy Clin. Immunol. 100: 632-641, 1997.
38. Sanico, A. M., G. Philip, D. Proud, R. M. Naclerio, and A. Togias. Neuronal responsiveness in nonallergic and allergic rhinitis: effects of capsaicin nasal challenge. Clin. Exp. Allergy 28: 92-100, 1998.
39. Saria, A., J. M. Lundberg, G. Skofitsch, and F. Lembeck. Vascular protein leakage in various tissues induced by substance P, capsaicin, bradykinin, serotonin, histamine and by antigen challenge. Naunyn Schmiedebergs Arch. Pharmacol. 324: 212-218, 1983.
40. Stelzner, T. J., C. H. Welsh, E. Berger, R. G. McCullough, K. Morris, J. E. Repine, and J. V. Weil. Antiarrhythmic agents diminish thiourea-induced pulmonary vascular protein leak in rats. J. Appl. Physiol. 63: 1877-1883, 1987.
41. Svensson, C., U. Pipkorn, U. Alkner, C. R. Baumgarten, and C. G. Persson. Topical vasoconstrictor oxymetazoline does not affect histamine-induced mucosal exudation of plasma in human nasal airways. Clin. Exp. Allergy 22: 411-416, 1992.