Association between HLA class II alleles and protection from or susceptibility to chronic hepatitis C

Journal of Hepatology

Volumn 28, Issue 1, 1998, Pages 1-7

  Zavaglia, Claudio ^a   Martinetti, Miryam ^b   Silini, Enrico ^c   Bottelli, Riccardo ^a   Daielli, Cristina ^b   Asti, Margherita ^c   Airoldi, Aldo ^a   Salvaneschi, Laura ^b   Mondelli, Mario U ^d   Ideo, Gaetano ^a  

^a OSPEDALE NIGUARDA CA GRANDA   (Italy)

^b Transfusion Medicine   (Italy)

^c Pathologic Anatomy   (Italy)

^d Infectious Diseases Department   (Italy)

Author keywords

Chronic hepatitis C; DNA typing; HCV; HLA

Indexed keywords

AMINOTRANSFERASE; HLA ANTIGEN CLASS 2; HLA DQ ANTIGEN; HLA DR ANTIGEN;

ADULT; AGED; ALLELE; AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; GENE AMPLIFICATION; GENE FREQUENCY; GENETIC ANALYSIS; GENOTYPE; HAPLOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN TISSUE; IMMUNOGENETICS; LIVER DISEASE; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0031952381     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(98)80195-5     Document Type: Article

References (31)

1. Alter MJ, Margolis HS, Krawczynski K, Judson FN, Mares A, Alexander WJ, et al. The natural history of community-acquired hepatitis C in the United States. N Engl J Med. 327:1992;1899-1905.
2. Tremolada F, Casarin C, Alberti A, Drago C, Tagger A, Ribero ML, et al. Long-term follow-up of non-A, non-B (type C)post-transfusion hepatitis. J Hepatol. 16:1992;273-281.
3. Silini E, Bono F, Cividini A, Cerino A, Bruno S, Rossi S, et al. Differential distribution of hepatitis C virus genotypes in patients with and without liver function abnormalities. Hepatology. 21:1995;285-290.
4. Lau JY, Davis GL, Kniffen J, Qian KP, Ureda MS, Chan CS, et al. Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lancet. 341:1993;1501-1504.
5. Mondelli MU. Is there a role for immune responses in the pathogenesis of hepatitis C? J Hepatol. 25:1996;232-238.
6. Spengler U, Lechmann M, Irrgang B, Dumoulin FL, Sauerbruch T. Immune responses in hepatitis C virus infection. J Hepatol. 24:1996;20-25. (Suppl. 2).
7. Germain RN. MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell. 76:1994;287-299.
8. Zavaglia C, Bortolon C, Ferrioli G, Rho A, Mondazzi L, Bottelli R, et al. HLA typing in chronic type B, D and C hepatitis. J Hepatol. 24:1996;658-665.
9. Blair CS, Haydon GH, McColl M, Yap PL, Hayes PC. HLA status and severity and progression of chronic hepatitis C [abstract]. Hepatology. 24:1996;149A.
10. Thursz MR, Mantafounis D, Yallop RM, Hewitt PE, Thomas HC. MHC class II and self limiting hepatitis C virus infection [abstract]. Hepatology. 24:1996;382A.
11. Peano G, Menardi G, Ponzetto A, Fenoglio LM. HLA-DR5 antigen - a genetic factor influencing the outcome of hepatitis C virus infection? Arch Intern Med. 154:1994;2733-2736.
12. Kuzushita N, Hayashi N, Katayama K, Hiramatsu N, Yasumaru M, Murata M, et al. Increased frequency of HLA DR13 in hepatitis C virus carriers with persistently normal ALT levels. J Med Virol. 48:1996;1-7.
13. Verdon R, Pol S, Landais P, Mattlinger B, Carnot F, Brechot C, et al. Absence of association between HLA antigens and chronicity of viral hepatitis in haemodialyzed patients. J Hepatol. 21:1994;388-393.
14. Vitte RL, Fortier C, Richardet JP, Grimbert S, Trinchet JC, Beaugrand M, et al. HLA antigens in patients with chronic hepatitis C. Tissue Antigens. 45:1995;356-61.
15. Svejgaard A, Platz P, Ryder LP. Insulin dependent diabetes mellitus. Terasaki PI. Histocompatibility testing 1980. 1980;638-656 UCLA Tissue Typing Laboratory, Los Angeles.
16. Todd JA, Mijovic C, Fletcher J, Jenkins D, Bradwell AR, Barnett AH. Identification of susceptibility loci for insulin-dependent diabetes mellitus by trans-racial gene mapping. Nature. 338:1989;587-589.
17. Ronningen KS, Spurkland A, Iwe T, Vartdal F, Thorsby E. Distribution of HLA-DRB1, -DQA1 and -DQB1 alleles and DQA1-DQB1 genotypes among Norwegian patients with insulin-dependent diabetes mellitus. Tissue Antigens. 37:1991;105-111.
18. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology. 19:1994;1513-1520.
19. De Groote J, Gedigk P, Popper H, Scheuer PJ, Thaler N, Desmet VJ, et al. A classification of chronic hepatitis. Lancet. ii:1968;626-628.
20. Scheuer PJ. Classification of chronic viral hepatitis: a need for reassessment. J Hepatol. 13:1991;372-374.
21. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucl Acids Res. 16:1988;1215.
22. Olerup O, Zetterquist H. HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor recipient matching in cadaveric transplantation. Tissue Antigens. 39:1992;225-235.
23. Czaja AJ, Carpenter H, Santrach PJ, Moore SB. DR human leukocyte antigens and disease severity in chronic hepatitis C. J Hepatol. 24:1996;666-673.
24. Marousis CG, She JX, She JY, Davis GL, Lau JYN. Differential prevalence of class II DQB1 but not DRB1 alleles in Caucasian patients with chronic hepatitis C [abstract]. Hepatology. 22:1995;349A.
25. Tibbs C, Donaldson P, Underhill J, Thomson L, Manabe K, Williams R. Evidence that the HLA DQA1*03 allele confers protection from chronic HCV-infection in Northern European Caucasoids. Hepatology. 24:1996;1342-1345.
26. Congia M, Clemente MG, Dessi C, Cucca F, Mazzoleni AP, Frau F, et al. HLA class II genes in chronic hepatitis C virus-infection and associated immunological disorders. Hepatology. 24:1996;1338-1341.
27. Mangia A, Cascavilla I, Lezzi G, De Maio G, Andriulli A. Different HLA class II haplotypes in antiHCV positive patients [abstract]. Hepatology. 24:1996;542A.
28. Kwok WW, Schwartz D, Nepom BS, Hock RA, Thurtle PS, Nepom GT. HLA-DQ molecules from α-β heterodimers of mixed allotype. J Immunol. 141:1988;3123-3127.
29. Sollid LM, Markussen G, Ek J, Gjerde H, Vartdal F, Thorsby E. Evidence for a primary association of celiac disease to a particular HLA-DQα/β heterodimer. J Exp Med. 169:1989;345-350.
30. Aikawa T, Kojima M, Onishi H, Tamura R, Fukuda S, Suzuki T, et al. HLA DRB1 and DQB1 alleles and haplotypes influencing the progression of hepatitis C. J Med Virol. 49:1996;274-278.
31. Zavaglia C, Belli LS, Alberti A, Silini E, Ideo G. Both immunogenetic factors and HCV genotypes can influence the outcome of chronic HCV infection. Am J Gastroenterol. 92:1997;725-726.