Peroxynitrite and hydrogen peroxide induced cell death in the NSC34 neuroblastoma x spinal cord cell line: Role of poly (ADP-ribose) polymerase

Journal of Neurochemistry

Volumn 70, Issue 2, 1998, Pages 501-508

  Cookson, Mark R ^a,b   Ince, Paul G ^a   Shaw, Pamela J ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE GENERAL HOSPITAL   (United Kingdom)

Author keywords

Free radicals; Motor neurone disease; Neurodegeneration; NSC34 cells; Peroxynitrite; Poly(ADP ribose) polymerase

Indexed keywords

DACTINOMYCIN; FREE RADICAL; HYDROGEN PEROXIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEROXYNITRITE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; HUMAN; HUMAN CELL; HYBRID CELL; MOTOR NEURON DISEASE; NERVE CELL DEGENERATION; NEUROBLASTOMA CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; SPINAL CORD MOTONEURON;

EID: 0031952034     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70020501.x     Document Type: Article

References (40)

1. Abe K., Pan L.-H., Watanabe M., Kato T., and Itoyama Y. (1995) Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis. Neurosci. Lett. 199, 152-154.
2. Banasik M., Komura H., Shimoyama M., and Ueda K. (1992) Specific inhibitors of poly(ADP-ribose)synthetase and mono (ADP-ribosyl)transferase. J. Biol. Chem. 267, 1569-1575.
3. Beal M. F. (1996) Mitochondria, free radicals and neurodegeneration. Curr. Opin. Neurobiol. 6, 661-666.
4. Beckman J. S., Carson M., Smith C. D., and Koppenol W. H. (1993) ALS, SOD and peroxynitrite. Nature 364, 584.
5. Bolaños J. P., Heales S. J. R., Land J. M., and Clark J. B. (1995) Effect of peroxynitrite on mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture. J. Neurochem. 64, 1965-1972.
6. Cashman N. R., Durham H. D., Blusztajn J. K., Oda K., Tabira T., Shaw I. T., Dahrouge S., and Antel J. P. (1992) Neuroblastoma × spinal cord (NSC) hybrid cell lines resemble developing motor neurons. Dev. Dyn. 194, 209-221.
7. Cookson M. R., Mead C., Austwick S. M., and Pentreath V. W. (1995) Use of the MTT assay for estimating toxicity in primary astrocyte and C6 glioma cell cultures. Toxicol. In Vitro 9, 39-48.
8. Cosi C., Chopin P., and Marien M. (1996a) Benzamide, an inhibitor of poly (ADP-ribose) polymerase attenuates methamphetamine-induced dopamine toxicity in the C57B1/6N mouse. Brain Res. 735, 343-348.
9. Cosi C., Colpaert F., Koek W., Degryse A., and Marien M. (1996b) Poly (ADP-ribose) polymerase inhibitors protect against MPTP-induced depletions of striatal dopamine and cortical noradrenaline in C57B1/6 mice. Brain Res. 729, 264-269.
10. Cosi C., Suzuki H., Milani D., Facci L., Menegazzi M., Vantini G., Kanai Y., and Skapper S. D. (1994) Poly (ADP-ribose) polymerase: early involvement in glutamate-induced neurotoxicity in cultured cerebellar granule cells. J. Neurosci. Res. 39, 38-46.
11. Durham H. D., Dahrouge S., and Cashman N. R. (1993) Evaluation of the spinal cord neuron × neuroblastoma hybrid cell line NSC34 as a model for neurotoxicity testing. Neurotoxicology 14, 387-396.
12. Estévez A. G., Radi R., Barbeito L., Shin J. T., Thompson J. A., and Beckman J. S. (1995) Peroxynitrite-induced cytotoxicity in PC12 cells: evidence for an apoptotic mechanism differentially modulated by neurotrophic factors. J. Neurochem. 65, 1543-1550.
13. Ischiropoulos H., Duran D., and Horwitz J. (1995) Peroxynitrite-mediated inhibition of DOPA synthesis in PC12 cells. J. Neurochem. 65, 2366-2372.
14. Kaufmann S. H., Desnoyers S., Ottaviano Y., Davidson N. E., and Poirier G. G. (1993) Specific proteolytic cleavage of poly (ADP-ribose); an early marker of chemotherapy-induced apoptosis. Cancer Res. 53, 3976-3985.
15. Koh J. Y. and Choi D. W. (1987) Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay. J. Neurosci. Methods 20, 83-90.
16. Küpper J. H., DeMurcia G., and Bürkle A. (1990) Inhibition of poly(ADP-ribosyl)ation by overexpressing the poly (ADP-ribose) polymerase DNA binding domain in mammalian cells. J. Biol. Chem. 265, 18721-18724.
17. Lafon-Cazal M., Pietri S., Culcasi M., and Bockaert J. (1993) NMDA-dependent superoxide production and neurotoxicity. Nature 364, 535-537.
18. Leist M., Single B., Künstle G., Volbracht C., Hentze H., and Nicotera P. (1997) Apoptosis in the absence of poly-(ADP-ribose) polymerase. Biochem. Biophys. Res. Commun. 233, 518-522.
19. Lin K.-T., Xue J.-Y., Nomen M., Spur B., and Wong P. Y.-K. (1995) Peroxynitrite-induced apoptosis in HL-60 cells. J. Biol. Chem. 270, 16487-16490.
20. Lipton S. A., Choi Y.-B., Pan Z.-H., Lei S. Z., Chen H.-S. V., Sucher N. J., Loscalzo J., Singel D. J., and Stamler J. S. (1993) A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 364, 626-632.
21. Olanow C. W. (1993) A radical hypothesis for neurodegeneration. Trends Neurosci. 16, 439-444.
22. Patel M., Day B. J., Crapo J. D., Fridovich I., and McNamara J. O. (1996) Requirement for superoxide in excitotoxic cell death. Neuron 16, 345-355.
23. Portera-Cailliau C., Price D. L., and Martin L. J. (1997a) Excitotoxic neuronal death in the immature brain is an apoptosis-necrosis morphological continuum. J. Comp. Neurol. 378, 70-87.
24. Portera-Cailliau C., Price D. L., and Martin L. J. (1997b) Non-NMDA and NMDA receptor-mediated excitotoxic neuronal deaths in adult brain are morphologically distinct: further evidence for an apoptosis-necrosis continuum. J. Comp. Neurol. 378, 88-104.
25. Pryor W. A., Cueto R., Jin X., Koppenol W. H., Ngu-Schwemlein M., Squadrito G. L., Uppu P. L., and Uppu R. M. (1995) A practical method for preparing peroxynitrite solutions of low ionic strength and free of hydrogen peroxide. Free Radic. Biol. Med. 18, 75-83.
26. Reynolds I. J. and Hastings I. G. (1995) Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J. Neurosci. 15, 3318-3327.
27. Rosen D. R., Siddique T., Patterson D., Figelwicz D. A., Sapp P., Hentati A., Donaldson D., Goto J., O'Regan J. P., Deng H.-X., Rahmani Z., Krizus A., McKenna-Yasek D., Cayabyab A., Gaston S. M., Berger R., Tanzi R. E., Halperin J. J., Herzfeldt B., VandenBergh R., Hung W.-Y., Bird T., Deng G., Mulder D. W., Smyth C., Laing N. G., Soriano E., Pericak-Vance M. A., Haines J., Rouleau G. A., Gusella J. S., Horvitz H. R., and Brown R. H. (1993) Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 59-62.
28. Salgo M. G., Squadrito G. L., and Pryor W. A. (1995) Peroxynitrite causes apoptosis in rat thymocytes. Biochem. Biophys. Res. Commun. 215, 1111-1118.
29. Sandoval M., Zhang X.-J., Liu X., Mannick E. E., Clark D. A., and Miller M. J. S. (1997) Peroxynitrite-induced apoptosis in T84 and RAW 264.7 cells: attenuation by L-ascorbic acid. Free Radic. Biol. Med. 22, 489-495.
30. Satoh M. S. and Lindahl T. (1992) Role of poly(ADP-ribose) formation in DNA repair. Nature 356, 356-358.
31. Schulz J. B., Henshaw D. R., Siwek D., Jenkins B. G., Ferrante R. J., Cipolloni P. B., Kowall N. W., Rosen B. G., and Beal M. F. (1995) Involvement of free radicals in excitotoxicity in vivo. J. Neurochem. 64, 2239-2247.
32. Sendtner M. and Thöenen H. (1994) Oxidative stress and motorneuron disease. Curr. Biol. 4, 1036-1039.
33. Szabó C., Zingarelli B., O'Connor M., and Salzman A. L. (1996a) DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity in macrophages and smooth muscle cells exposed to peroxynitrite. Proc. Natl. Acad. Sci. USA 93, 1753-1758.
34. Szabó C., Zingarelli B., and Salzman A. L. (1996b) Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite. Circ. Res. 78, 1051-1063.
35. Tewari M., Quan L. T., O'Rourke K., Desnoyers S., Zheng Z., Beidler D. R., Poirier G. G., Slavesen G. S., and Dixit V. M. (1995) Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase. Cell 81, 801-809.
36. 2 but not apoptosis. Gastroenterology 109, 472-482.
37. Whittemore E. R., Loo D. T., and Cotman C. W. (1994) Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons. Neuroreport 5, 1485-1488.
38. Yakes F. M. and VanHouten B. (1997) Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc. Natl. Acad. Sci. USA 94, 514-519.
39. Zhang J., Dawson V. L., Dawson T. M., and Snyder S. H. (1994) Nitric oxide activation of poly (ADP-ribose) synthetase in neurotoxicity. Science 263, 687-689.
40. Zhang J., Pieper A., and Snyder S. H. (1995) Poly(ADP-ribose) synthetase activation: an early indicator of neurotoxic DNA damage. J. Neurochem. 65, 1411-1414.