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Volumn 64, Issue 3, 1998, Pages 824-829

Engineering of plasmin-resistant forms of streptokinase and their production in Bacillus subtilis: Streptokinase with longer functional half- life

Author keywords

[No Author keywords available]

Indexed keywords

PLASMIN; STREPTOKINASE;

EID: 0031951905     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/aem.64.3.824-829.1998     Document Type: Article
Times cited : (49)

References (51)
  • 1
    • 0017353766 scopus 로고
    • Activation of human plasminogen by equimolar levels of streptokinase
    • Bajaj, A. P., and F. J. Castellino. 1977. Activation of human plasminogen by equimolar levels of streptokinase. J. Biol. Chem. 252:492-498.
    • (1977) J. Biol. Chem. , vol.252 , pp. 492-498
    • Bajaj, A.P.1    Castellino, F.J.2
  • 2
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding
    • Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 3
    • 0029097037 scopus 로고
    • Prolonged half-life in the circulation of a chemical conjugate between a pro-urokinase derivative and human serum albumin
    • Breton, J., N. Pezzi, A. Molinari, L. Bonomini, J. Lansen, G. Gonzalez De Buitrago, and I. Prieto. 1995. Prolonged half-life in the circulation of a chemical conjugate between a pro-urokinase derivative and human serum albumin. Eur. J. Biochem. 231:563-569.
    • (1995) Eur. J. Biochem. , vol.231 , pp. 563-569
    • Breton, J.1    Pezzi, N.2    Molinari, A.3    Bonomini, L.4    Lansen, J.5    Gonzalez De Buitrago, G.6    Prieto, I.7
  • 4
    • 0016237609 scopus 로고
    • A characterization of native streptokinase and altered streptokinase isolated from a human plasminogen activator complex
    • Brockway, W. J., and F. J. Castellino. 1974. A characterization of native streptokinase and altered streptokinase isolated from a human plasminogen activator complex. Biochemistry 13:2063-2070.
    • (1974) Biochemistry , vol.13 , pp. 2063-2070
    • Brockway, W.J.1    Castellino, F.J.2
  • 5
    • 0025365377 scopus 로고
    • Catabolism of streptokinase and polyethylene glycol-streptokinase: Evidence for transport of intact forms through the biliary system in the mouse
    • Brucato, F. H., and S. V. Pizzo. 1990. Catabolism of streptokinase and polyethylene glycol-streptokinase: evidence for transport of intact forms through the biliary system in the mouse. Blood 76:73-79.
    • (1990) Blood , vol.76 , pp. 73-79
    • Brucato, F.H.1    Pizzo, S.V.2
  • 6
    • 0028960265 scopus 로고
    • The importance of rapidly treating patients with acute myocardial infarction
    • Cannon, C. P., and S. Z. Goldhaber. 1995. The importance of rapidly treating patients with acute myocardial infarction. Chest 107:598-600.
    • (1995) Chest , vol.107 , pp. 598-600
    • Cannon, C.P.1    Goldhaber, S.Z.2
  • 8
    • 0025219617 scopus 로고
    • Plasminogen activator activities of equimolar complexes of streptokinase with variant recombinant plasminogens
    • Davidson, D. J., D. L. Higgins, and F. J. Castellino. 1990. Plasminogen activator activities of equimolar complexes of streptokinase with variant recombinant plasminogens. Biochemistry 29:3585-3590.
    • (1990) Biochemistry , vol.29 , pp. 3585-3590
    • Davidson, D.J.1    Higgins, D.L.2    Castellino, F.J.3
  • 9
    • 0014932863 scopus 로고
    • Plasminogen: Purification from human plasma by affinity chromatography
    • Deutsch, D. G., and E. T. Mertz. 1970. Plasminogen: purification from human plasma by affinity chromatography. Science 170:1095-1096.
    • (1970) Science , vol.170 , pp. 1095-1096
    • Deutsch, D.G.1    Mertz, E.T.2
  • 10
    • 0025335032 scopus 로고
    • GISSI-2: A factorial randomised trial of alteplase versus streptokinase and heparin versus no heparin among 12,490 patients with acute myocardial infarction
    • Gruppo Italiano Per Lo Studio Della Sopravvivenza Nell'Infarto Miocardico. 1990. GISSI-2: a factorial randomised trial of alteplase versus streptokinase and heparin versus no heparin among 12,490 patients with acute myocardial infarction. Lancet 336:65-71.
    • (1990) Lancet , vol.336 , pp. 65-71
  • 11
    • 0027424433 scopus 로고
    • The effects of tissue plasminogen activator, streptokinase, or both on coronary-artery patency, ventricular function, and survival after acute myocardial infarction
    • GUSTO Angiographic Investigators. 1993. The effects of tissue plasminogen activator, streptokinase, or both on coronary-artery patency, ventricular function, and survival after acute myocardial infarction. N. Engl. J. Med. 329: 1615-1622.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 1615-1622
  • 12
    • 0027240597 scopus 로고
    • An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction
    • 11a. GUSTO Angiographic Investigators. 1993. An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. N. Engl. J. Med. 329:673-682.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 673-682
  • 13
    • 0017698858 scopus 로고
    • Zinc is associated with the beta subunit of DNA dependent RNA polymerase of Bacillus subtilis
    • Halling, S. M., F. J. Sanchez-Anzaldo, R. Fukuda, R. H. Doi, and C. F. Meares. 1977. Zinc is associated with the beta subunit of DNA dependent RNA polymerase of Bacillus subtilis. Biochemistry 16:2880-2884.
    • (1977) Biochemistry , vol.16 , pp. 2880-2884
    • Halling, S.M.1    Sanchez-Anzaldo, F.J.2    Fukuda, R.3    Doi, R.H.4    Meares, C.F.5
  • 14
    • 0024357799 scopus 로고
    • A simple method for site-directed mutagenesis using the polymerase chain reaction
    • Hemsley, A., N. Arnheim, M. D. Toney, G. Cortopassi, and D. J. Galas. 1989. A simple method for site-directed mutagenesis using the polymerase chain reaction. Nucleic Acids Res. 17:6545-6551.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 6545-6551
    • Hemsley, A.1    Arnheim, N.2    Toney, M.D.3    Cortopassi, G.4    Galas, D.J.5
  • 16
    • 0345343901 scopus 로고
    • Construction of a recombinant streptokinase that resists cleavage and inactivation by plasmin
    • Abstract
    • Houng, A., S. Quen, L.-F. Jean, and G. L. Reed. 1995. Construction of a recombinant streptokinase that resists cleavage and inactivation by plasmin. Thromb. Haemostasis 73:1130. (Abstract.)
    • (1995) Thromb. Haemostasis , vol.73 , pp. 1130
    • Houng, A.1    Quen, S.2    Jean, L.-F.3    Reed, G.L.4
  • 17
    • 0029914343 scopus 로고    scopus 로고
    • Thrombolytic therapy in acute myocardial infarction
    • Huber, K. and G. Maurer. 1996. Thrombolytic therapy in acute myocardial infarction. Semin. Thromb. Hemostasis 22:15-26.
    • (1996) Semin. Thromb. Hemostasis , vol.22 , pp. 15-26
    • Huber, K.1    Maurer, G.2
  • 18
    • 0026607185 scopus 로고
    • ISIS-3: A randomised comparison of streptokinase vs tissue plasminogen activator vs anistreplase and of aspirin plus heparin vs aspirin alone among 41 299 cases of suspected acute myocardial infarction
    • ISIS-3 Collaborative Group. 1992. ISIS-3: A randomised comparison of streptokinase vs tissue plasminogen activator vs anistreplase and of aspirin plus heparin vs aspirin alone among 41 299 cases of suspected acute myocardial infarction. Lancet 339:753-770.
    • (1992) Lancet , vol.339 , pp. 753-770
  • 19
    • 0022535440 scopus 로고
    • Active streptokinase from the cloned gene in Streptococcus sanguis is without the carboxyl-terminal 32 residues
    • Jackson, K. W., H. Malke, D. Gerlach, J. J. Ferretti, and J. Tang. 1986. Active streptokinase from the cloned gene in Streptococcus sanguis is without the carboxyl-terminal 32 residues. Biochemistry 25:108-114.
    • (1986) Biochemistry , vol.25 , pp. 108-114
    • Jackson, K.W.1    Malke, H.2    Gerlach, D.3    Ferretti, J.J.4    Tang, J.5
  • 21
    • 0029963497 scopus 로고    scopus 로고
    • C-terminal peptide of streptokinase, Met369-Pro373, is important in plasminogen activation
    • Kim, I. C., J. S. Kim, S. H. Lee, and S. M. Byun. 1996. C-terminal peptide of streptokinase, Met369-Pro373, is important in plasminogen activation. Biochem. Mol. Biol. Int. 40:939-945.
    • (1996) Biochem. Mol. Biol. Int. , vol.40 , pp. 939-945
    • Kim, I.C.1    Kim, J.S.2    Lee, S.H.3    Byun, S.M.4
  • 22
    • 0024791634 scopus 로고
    • Site-specific alteration of Gly-24 in streptokinase: Its effect on plasminogen activation
    • Lee, B. R., S. K. Park, J. H. Kim, and S. M. Byun. 1989. Site-specific alteration of Gly-24 in streptokinase: its effect on plasminogen activation. Biochem. Biophys. Res. Commun. 165:1085-1090.
    • (1989) Biochem. Biophys. Res. Commun. , vol.165 , pp. 1085-1090
    • Lee, B.R.1    Park, S.K.2    Kim, J.H.3    Byun, S.M.4
  • 23
    • 0031051701 scopus 로고    scopus 로고
    • Identification of the functional importance of valine-19 residue in streptokinase by N-terminal deletion and site-directed mutagenesis
    • Lee, S. H., S. T. Jeong, I. C. Kim, and S. M. Byun. 1997. Identification of the functional importance of valine-19 residue in streptokinase by N-terminal deletion and site-directed mutagenesis. Biochem. Mol. Biol. Int. 41:199-207.
    • (1997) Biochem. Mol. Biol. Int. , vol.41 , pp. 199-207
    • Lee, S.H.1    Jeong, S.T.2    Kim, I.C.3    Byun, S.M.4
  • 24
    • 0030452422 scopus 로고    scopus 로고
    • Mutation of lysines in a plasminogen binding region of streptokinase identifies residues important for generating a functional activator complex
    • Lin, L. F., S. Oeun, A. Houng, and G. L. Reed. 1996. Mutation of lysines in a plasminogen binding region of streptokinase identifies residues important for generating a functional activator complex. Biochemistry 35:16879-16885.
    • (1996) Biochemistry , vol.35 , pp. 16879-16885
    • Lin, L.F.1    Oeun, S.2    Houng, A.3    Reed, G.L.4
  • 25
    • 0027933043 scopus 로고
    • Probing structure-function relationships of tissue-plasminogen activator by site-specific mutagenesis
    • Madison, E. 1994. Probing structure-function relationships of tissue-plasminogen activator by site-specific mutagenesis. Fibrinolysis 8:221-236.
    • (1994) Fibrinolysis , vol.8 , pp. 221-236
    • Madison, E.1
  • 26
    • 0021245163 scopus 로고
    • Streptokinase: Cloning, expression, and excretion by Escherichia coli
    • Malke, H., and J. J. Ferretti. 1984. Streptokinase: cloning, expression, and excretion by Escherichia coli. Proc. Natl. Acad. Sci. USA 81:3557-3561.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 3557-3561
    • Malke, H.1    Ferretti, J.J.2
  • 27
    • 0023664635 scopus 로고
    • Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes
    • Matsudaira, P. 1987. Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes. J. Biol. Chem. 262: 10035-10038.
    • (1987) J. Biol. Chem. , vol.262 , pp. 10035-10038
    • Matsudaira, P.1
  • 28
    • 0024320642 scopus 로고
    • Early versus late hospital arrival for acute myocardial infarction in the Western Washington Thrombolytic Therapy Trials
    • Maynard, C., R. Althouse, M. Olsufka, J. L. Ritchie, K. B. Davis, and J. W. Kennedy. 1989. Early versus late hospital arrival for acute myocardial infarction in the Western Washington Thrombolytic Therapy Trials. Am. J. Cardiol. 63:1296-1300.
    • (1989) Am. J. Cardiol. , vol.63 , pp. 1296-1300
    • Maynard, C.1    Althouse, R.2    Olsufka, M.3    Ritchie, J.L.4    Davis, K.B.5    Kennedy, J.W.6
  • 29
    • 0016290372 scopus 로고
    • Two distinct pathways of the streptokinase-mediated activation of highly purified human plasminogen
    • McClinock, D. K., M. E. Englert, C. Dziobkowski, E. H. Snedeker, and P. H. Bell. 1974. Two distinct pathways of the streptokinase-mediated activation of highly purified human plasminogen. Biochemistry 13:5334-5344.
    • (1974) Biochemistry , vol.13 , pp. 5334-5344
    • McClinock, D.K.1    Englert, M.E.2    Dziobkowski, C.3    Snedeker, E.H.4    Bell, P.H.5
  • 30
    • 0029620638 scopus 로고
    • Streptokinase contains two independent plasminogen-binding sites
    • Nihalani, D., and G. Sahni. 1995. Streptokinase contains two independent plasminogen-binding sites. Biochem. Biophys. Res. Commun. 217:1245-1254.
    • (1995) Biochem. Biophys. Res. Commun. , vol.217 , pp. 1245-1254
    • Nihalani, D.1    Sahni, G.2
  • 31
    • 0028049159 scopus 로고
    • Halving of mortality at 1 year by domiciliary thrombolysis in the Grampian Region Early Anistreplase Trial (GREAT)
    • Rawles, J. 1994. Halving of mortality at 1 year by domiciliary thrombolysis in the Grampian Region Early Anistreplase Trial (GREAT). J. Am. Coll. Cardiol. 23:1-5.
    • (1994) J. Am. Coll. Cardiol. , vol.23 , pp. 1-5
    • Rawles, J.1
  • 32
    • 0029079778 scopus 로고
    • Identification of a plasminogen binding region in streptokinase that is necessary for the creation of a functional streptokinase-plasminogen activator complex
    • Reed, G. L., L.-F. Lin, B. Parhami-Seren, and P. Kussie. 1995. Identification of a plasminogen binding region in streptokinase that is necessary for the creation of a functional streptokinase-plasminogen activator complex. Biochemistry 34:10266-10271.
    • (1995) Biochemistry , vol.34 , pp. 10266-10271
    • Reed, G.L.1    Lin, L.-F.2    Parhami-Seren, B.3    Kussie, P.4
  • 37
    • 0019450328 scopus 로고
    • Radial caseinolysis in agarose: A simple method for detection of plasminogen activators in the presence of inhibitory substances and serum
    • Saksela, O. 1981. Radial caseinolysis in agarose: a simple method for detection of plasminogen activators in the presence of inhibitory substances and serum. Anal. Biochem. 111:276-282.
    • (1981) Anal. Biochem. , vol.111 , pp. 276-282
    • Saksela, O.1
  • 38
    • 0030614529 scopus 로고    scopus 로고
    • Staphylokinase requires NH2-terminal proteolysis for plasminogen activation
    • Schlott, B., K. H. Guhrs, M. Hartmann, A. Rocker, and D. Collen. 1997. Staphylokinase requires NH2-terminal proteolysis for plasminogen activation. J. Biol. Chem. 272:6067-6072.
    • (1997) J. Biol. Chem. , vol.272 , pp. 6067-6072
    • Schlott, B.1    Guhrs, K.H.2    Hartmann, M.3    Rocker, A.4    Collen, D.5
  • 39
    • 0027985626 scopus 로고
    • Function of streptokinase fragments in plasminogen activation
    • Shi, G.-Y., B.-I. Chang, S.-M. Chen, D.-H. Wu, and H.-L. Wu. 1994. Function of streptokinase fragments in plasminogen activation. Biochem. J. 304:235-241.
    • (1994) Biochem. J. , vol.304 , pp. 235-241
    • Shi, G.-Y.1    Chang, B.-I.2    Chen, S.-M.3    Wu, D.-H.4    Wu, H.-L.5
  • 40
    • 0017126765 scopus 로고
    • Interaction of streptokinase with plasminogen: Isolation and characterization of a streptokinase degradation product
    • Siefring, G. E., Jr. and F. J. Castellino. 1976. Interaction of streptokinase with plasminogen: isolation and characterization of a streptokinase degradation product. J. Biol. Chem. 251:3913-3920.
    • (1976) J. Biol. Chem. , vol.251 , pp. 3913-3920
    • Siefring Jr., G.E.1    Castellino, F.J.2
  • 41
    • 0019864396 scopus 로고
    • Fibrinolysis with acyl-enzymes: A new approach to thrombolytic therapy
    • Smith, R. A., R. J. Dupe, P. D. English, and J. Green. 1981. Fibrinolysis with acyl-enzymes: a new approach to thrombolytic therapy. Nature 290:505-508.
    • (1981) Nature , vol.290 , pp. 505-508
    • Smith, R.A.1    Dupe, R.J.2    English, P.D.3    Green, J.4
  • 42
    • 0021829611 scopus 로고
    • The DNA sequence of the secreted Bacillus subtilis enzyme levansucrase and its genetic control sites
    • Steinmetz, M., D. LeCoq, S. Aymerich, G. Gonzy-Treboul, and P. Gay. 1985. The DNA sequence of the secreted Bacillus subtilis enzyme levansucrase and its genetic control sites. Mol. Gen. Genet. 200:220-228.
    • (1985) Mol. Gen. Genet. , vol.200 , pp. 220-228
    • Steinmetz, M.1    LeCoq, D.2    Aymerich, S.3    Gonzy-Treboul, G.4    Gay, P.5
  • 43
    • 0015919736 scopus 로고
    • 2-terminal lysine forms of human plasminogen isolated by affinity chromatography and isoelectric focusing methods
    • 2-terminal lysine forms of human plasminogen isolated by affinity chromatography and isoelectric focusing methods. J. Biol. Chem. 248:2984-2991.
    • (1973) J. Biol. Chem. , vol.248 , pp. 2984-2991
    • Summaria, L.1    Arzadon, L.2    Bernabe, P.3    Robbins, K.C.4    Barlow, G.5
  • 45
    • 0027176652 scopus 로고
    • The Myocardial Infarction Triage and Intervention Project Group: Prehospital-initiated vs hospital-initiated thrombolytic therapy. The Myocardial Infarction Triage and Intervention Trial
    • Weaver, W. D., M. Cerqueira, A. P. Hallstrom, P. E. Litwin, J. S. Martin, P. J. Kudenchuk, and M. Eisenberg. 1993. The Myocardial Infarction Triage and Intervention Project Group: prehospital-initiated vs hospital-initiated thrombolytic therapy. The Myocardial Infarction Triage and Intervention Trial. JAMA 270:1211-1216.
    • (1993) JAMA , vol.270 , pp. 1211-1216
    • Weaver, W.D.1    Cerqueira, M.2    Hallstrom, A.P.3    Litwin, P.E.4    Martin, J.S.5    Kudenchuk, P.J.6    Eisenberg, M.7
  • 46
    • 0015526560 scopus 로고
    • Differential specificities of thrombin, plasmin and trypsin with regard to synthetic and natural substrates and inhibitors
    • Weinstein, M. J. and R. F. Doolittle. 1972. Differential specificities of thrombin, plasmin and trypsin with regard to synthetic and natural substrates and inhibitors. Biochim. Biophys. Acta 258:577-582.
    • (1972) Biochim. Biophys. Acta , vol.258 , pp. 577-582
    • Weinstein, M.J.1    Doolittle, R.F.2
  • 47
    • 0018898952 scopus 로고
    • Kinetics of activation of human plasminogen by different activator species at pH 7.4 and 37 degrees C
    • Wohl, R. C., L. Summaria, and K. C. Robbins. 1980. Kinetics of activation of human plasminogen by different activator species at pH 7.4 and 37 degrees C. J. Biol. Chem. 255:2005-2013.
    • (1980) J. Biol. Chem. , vol.255 , pp. 2005-2013
    • Wohl, R.C.1    Summaria, L.2    Robbins, K.C.3
  • 48
    • 0024305946 scopus 로고
    • Development of an inducible and enhancible expression and secretion system in Bacillus subtilis
    • Wong, S.-L. 1989. Development of an inducible and enhancible expression and secretion system in Bacillus subtilis. Gene 83:215-223.
    • (1989) Gene , vol.83 , pp. 215-223
    • Wong, S.-L.1
  • 49
    • 0028012475 scopus 로고
    • Engineering and production of streptokinase in a Bacillus subtilis expression-secretion system
    • Wong, S.-L., R. Ye, and S. Nathoo. 1994. Engineering and production of streptokinase in a Bacillus subtilis expression-secretion system. Appl. Environ. Microbiol. 60:517-523.
    • (1994) Appl. Environ. Microbiol. , vol.60 , pp. 517-523
    • Wong, S.-L.1    Ye, R.2    Nathoo, S.3
  • 50
    • 0026338822 scopus 로고
    • Engineering a Bacillus subtilis expression-secretion system with a strain deficient in six extracellular proteases
    • Wu, X.-C., W. Lee, L. Tran, and S.-L. Wong. 1991. Engineering a Bacillus subtilis expression-secretion system with a strain deficient in six extracellular proteases. J. Bacteriol. 173:4952-4958.
    • (1991) J. Bacteriol. , vol.173 , pp. 4952-4958
    • Wu, X.-C.1    Lee, W.2    Tran, L.3    Wong, S.-L.4


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