Activation of heterologous gene expression by the large isoform of hepatitis delta antigen

Journal of Virology

Volumn 72, Issue 3, 1998, Pages 2089-2096

  Wei, Y U ^a,b   Ganem, Don ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS DELTA ANTIGEN;

AMINO ACID SUBSTITUTION; ARTICLE; HEPATITIS B VIRUS; HEPATITIS DELTA VIRUS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSACTIVATION;

EID: 0031951651     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.3.2089-2096.1998     Document Type: Article

References (41)

1. Bichko, V., S. Bank, and J. Taylor. 1997. Phosphorylation of the hepatitis delta virus antigens. J. Virol. 71:512-518.
2. Bichko, V. V., and J. M. Taylor. 1996. Redistribution of the delta antigens in cells replicating the genome of hepatitis delta virus. J. Virol. 70:8064-8070.
3. Bonino, F., K. H. Heermann, M. Rizzetto, and W. H. Gerlich. 1986. Hepatitis delta virus: protein composition of delta antigen and its hepatitis B virus-derived envelope. J. Virol. 58:945-950.
4. Bonino, F., F. Negro, M. Baldi, M. R. Brunetto, E. Chiaberge, M. Capalbo, E. Maran, C. Lavarini, N. Rocca, and G. Rocca. 1987. The natural history of chronic delta hepatitis, vol. 234. Alan R. Liss, New York, N.Y.
5. Brazas, R., and D. Ganem. 1996. A cellular homolog of hepatitis delta antigen: implications for viral replication and evolution. Science 274:90-94.
6. 5a. Brazas, R., and D. Ganem. Unpublished data.
7. Chang, F. L., S. J. Chen, S. J. Tu, M. N. Chiu, C. J. Wang, and D. S. Chen. 1991. The large form of hepatitis delta antigen is crucial for the assembly of hepatitis delta virus. Proc. Natl. Acad. Sci. USA 88:8490-8494.
8. Chang, M. F., S. C. Baker, L. H. Soe, T. Kamahora, J. G. Keck, S. Makino, S. Govindajajan, and M. M. C. Lai. 1988. Human hepatitis delta antigen is a nuclear phosphoprotein with RNA-binding activity. J. Virol. 62:2403-2410.
9. Chao, M., S.-Y. Hsieh, and J. Taylor. 1990. Role of two forms of the hepatitis delta virus antigen: evidence for a mechanism of self-limiting genome replication. J. Virol. 64:5066-5069.
10. Cicchetti, P., B. J. Mayer, G. Thiel, and B. Baltimore. 1992. Identification of a protein that binds to the SH3 region of abl and is similar to Bcr and GAP-rho. Science 257:803-806.
11. Cohen, D. R., and T. Curran. 1988. fra-1, a serum-inducible, cellular immediate-early gene that encodes a Fos-related antigen. Mol. Cell. Biol. 8:2063-2069.
12. Doria, M., N. Klein, R. Lucito, and R. J. Schneider. 1995. The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors. EMBO J. 14:4747-4757.
13. Engler-Blum, G., M. Meier, J. Frank, and G. A. Müller. 1993. Reduction of background problems in nonradioactive Northern and Southern blot analyses enables higher sensitivity than 32P-based hybridizations. Anal. Biochem. 210:235-244.
14. Fourel, G., C. Transy, B. C. Tennant, and M. A. Buendia. 1992. Expression of the woodchuck N-myc2 retroposon in brain and in liver tumors is driven by a cryptic N-myc promoter. Mol. Cell. Biol. 12:5336-5344.
15. Fourel, G., C. Trépo, L. Bougueleret, B. Henglein, A. Ponzetto, P. Tiollais, and M. A. Buendia. 1990. Frequent activation of N-myc genes by hepadna-virus insertion in woodchuck liver tumours. Nature 347:294-298.
16. Fu, T.-B., and J. Taylor. 1993. The RNAs of hepatitis delta virus are copied by RNA polymerase II in nuclear homogenates. J. Virol. 67:6965-6972.
17. Glenn, J. S., J. A. Watson, C. M. Havel, and J. M. White. 1992. Identification of a prenylation site in delta virus large antigen. Science 256:1331-1333.
18. Guo, W., M. Chen, T. S. B. Yen, and J. Ou. 1993. Hepatocyte-specific expression of the hepatitis B virus core promoter depends on both positive and negative regulation. Mol. Cell. Biol. 13:443-448.
19. Hwang, S. B., and M. M. C. Lai. 1994. Isoprenylation masks a conformational epitope and enhances trans-dominant inhibitory function of the large hepatitis delta antigen. J. Virol. 68:2958-2964.
20. Kuo, M. Y.-P., M. Chao, and J. Taylor. 1989. Initiation of replication of the human hepatitis delta virus genome from cloned DNA: role of delta antigen. J. Virol. 63:1945-1950.
21. Lai, M. M. C. 1995. The molecular biology of hepatitis delta virus. Annu. Rev. Biochem. 64:259-286.
22. Lazinski, D. W., and J. M. Taylor. 1994. Recent developments in hepatitis delta virus research. Adv. Virus Res. 43:187-231.
23. Lazinski, D. W., and J. M. Taylor. 1993. Relating structure to function in the hepatitis delta virus antigen. J. Virol. 67:2672-2680.
24. Lin, J.-H., M.-F. Chang, S. C. Baker, S. Govindarajan, and M. M. C. Lai. 1990. Characterization of hepatitis delta antigen: specific binding to hepatitis delta virus RNA. J. Virol. 64:4051-4058.
25. Lukac, D. M., J. R. Manuppello, and J. C. Alwine. 1994. Transcriptional activation by the human cytomegalovirus immediate-early proteins: requirements for simple promoter structures and interactions with multiple components of the transcription complex. J. Virol. 68:5184-5193.
26. Luo, G., M. Chao, S.-Y. Hsieh, C. Sureau, K. Nishikura, and J. Taylor. 1990. A specific base transition occurs on replicating hepatitis delta virus RNA. J. Virol. 64:1021-1027.
27. MacNaughton, T. B., E. J. Gowans, S. P. McNamara, and C. J. Burrell. 1991. Hepatitis delta antigen is necessary for access of hepatitis delta virus RNA to the cell transcriptional machinery but is not part of the transcriptional complex. Virology 184:387-390.
28. Otto, J. C., and P. J. Casey. 1996. The hepatitis delta virus large antigen is farnesylated both in vitro and in animal cells. J. Biol. Chem. 27:4569-4572.
29. Ponzetto, A., P. J. Cote, H. Popper, B. H. Boyer, W. T. London, E. C. Ford, F. Bonino, R. H. Purcell, and J. L. Gerin. 1984. Transmission of the hepatitis B-associated delta agent to the eastern woodchuck. Proc. Natl. Acad. Sci. USA 81:2208-2212.
30. Rizzetto, M., M. G. Canese, J. Arico, O. Crivelli, F. Bonino, C. G. Trepo, and G. Verme. 1977. Immunofluorescence detection of a new antigen-antibody system associated to the hepatitis B virus in the liver and in the serum of HDsAg carriers. Gut 18:997-1003.
31. Rizzetto, M., M. G. Canese, J. L. Gerin, W. T. London, D. L. Sly, and R. H. Purcell. 1980. Transmission of the hepatitis B virus-associated delta antigen to chimpanzees. J. Infect. Dis. 141:590-602.
32. Rizzetto, M., B. Hoyer, M. G. Canese, J. W.-K. Shih, R. H. Purcell, and J. L. Gerin. 1980. Delta agent: association of delta antigen with hepatitis B surface antigen and RNA in serum of delta-infected chimpanzees. Proc. Natl. Acad. Sci. USA 77:6124-6128.
33. Saracco, G., S. Macagno, F. Rosina, and M. Rizzetto. 1988. Serologic markers with fulminant hepatitis in persons positive for hepatitis B surface antigen. A worldwide epidemiologic and clinical survey. Ann. Intern. Med. 108:380.
34. Taylor, I. C. A., and R. E. Kingston. 1990. Factor substitution in a human HSP70 gene promoter: TATA-dependent and TATA-independent interactions. Mol. Cell. Biol. 10:165-175.
35. Taylor, J., W. Mason, J. Summers, J. Goldberg, C. Aldrich, L. Coates, J. Gerin, and E. Gowans. 1987. Replication of human hepatitis delta virus in primary cultures of woodchuck hepatocytes. J. Virol. 61:2891-2895.
36. Ueda, K., Y. Wei, and D. Ganem. 1996. Activation of N-myc2 gene expression by cis-acting elements of oncogenic hepadnaviral genomes: key role of enhancer II. Virology 217:413-417.
37. Ueda, K., Y. Wei, and D. Ganem. 1996. Cellular factors controlling the activity of woodchuck hepatitis virus enhancer II. J. Virol. 70:4714-4723.
38. Wang, J.-G., and S. M. Lemon. 1993. Hepatitis delta virus antigen forms dimers and multimeric complexes in vivo. J. Virol. 67:446-454.
39. Weiner, A. J., Q.-L. Choo, K.-S. Wang, S. Govindarajan, A. G. Redeker, J. L. Gerin, and M. Houghton. 1988. A single antigenomic open reading frame of the hepatitis delta virus encodes the epitope(s) of both hepatitis delta antigen polypeptides p24δ and p27δ. J. Virol. 62:594-599.
40. Wu, J.-C., P.-J. Chen, M. Y. P. Kuo, S.-D. Lee, D.-S. Chen, and L.-P. Ting. 1991. Production of hepatitis delta virus and suppression of helper hepatitis B virus in a human hepatoma cell line. J. Virol. 65:1099-1104.
41. Zhou, D., and T. S. B. Yen. 1990. Differential regulation of the hepatitis B virus surface gene promoters by a second viral enhancer. J. Biol. Chem. 265:20731-20734.