A functional model of hepatocyte transplantation for in vivo immunologic studies

Transplantation

Volumn 65, Issue 1, 1998, Pages 53-61

  Bumgardner, Ginny L ^a,b   Heininger, Marie ^a   Jiashun, L I ^a   Xia, Dongyuan ^a   Parker Thornburg, Jan ^a   Ferguson, Ronald M ^a   Orosz, Charles G ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL MODEL; ARTICLE; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNE RESPONSE; LIVER TRANSPLANTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TRANSGENIC MOUSE;

ALPHA 1-ANTITRYPSIN; ANIMALS; DISEASE MODELS, ANIMAL; GRAFT SURVIVAL; HALF-LIFE; HUMANS; IMMUNOENZYME TECHNIQUES; LIVER TRANSPLANTATION; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; POLYMERASE CHAIN REACTION; SPLENECTOMY;

EID: 0031951618     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199801150-00011     Document Type: Article

References (44)

1. Bumgardner GL, Chen S, Hoffman RA, et al. Afferent and efferent pathways in T cell responses to MHC class II-hepatocytes. Transplantation 1989; 47(1): 163.
2. Bumgardner GL, Ascher NL, Cahill D, et al. Comparison of in vivo and in vitro immune response to purified hepatocytes. Transplantation 1990; 49: 429.
3. Bumgardner GL, Chen SC, Almond PS, Bach FH, Ascher NL, Matas AJ. Cell subsets responding to purified hepatocytes and evidence of indirect recognition of hepatocyte major histocompatibility complex class I antigen. I. The role of L3T4+ T cells in the development of allospecific cytotoxicity in hepatocyte-sponge matrix allografts. Transplantation 1992; 53: 857.
4. Bumgardner GL, Chen SC, Almond PS, Bach FH, Ascher NL, Matas AJ. Cell subsets responding to purified hepatocytes and evidence of indirect recognition of hepatocyte major histocompatibility complex class I antigen. II. In vitro-generated "memory" cells to class I+ class II- hepatocytes. Transplantation 1992; 53(4): 863.
5. Wiederkehr JC, Kondos GT, Pollak R. Hepatocyte transplantation for the low-density lipoprotein receptor-deficient state: a study in the Watanabe rabbit.. Transplantation 1990; 50(3): 466.
6. Onodera K, Kasai S, Kato K, Nakazawa F, Mito M. Long-term effect of intrasplenic hepatocyte transplantation in congenitally ascorbic acid biosynthetic enzyme-deficient rats. Cell Transpl 1995; 4 (suppl 1): S41.
7. Cobourn CS, Makowka L, Falk JA, Falk RE. Allogeneic intrasplenic hepatocyte transplantation in the Gunn rat using cyclosporine A immunosuppression. Transplant Proc 1987; 19(1 Pt 2): 1002.
8. Rozga J, Holzman M, Moscioni AD, Fujioka H, Morsiani E. Repeated intraportal hepatocyte transplantation in analbuminemic rats. Cell Transplant 1995; 4(2): 237.
9. Kay MA, Rothenberg S, Landen CN, et al. Current therapeutic relevance of liver gene transfer. Hepatology 1994; 20: 253.
10. Matas AJ, Sutherland DER, Steffes MW. Hepatocellular transplantation for metabolic deficiencies: decrease of plasma bilirubin in Gunn rats. Science 1976; 192; 892.
11. Holzman MD, Rozga J, Neuzil DF, Griffin D, Moscioni AD, Demetriou AA. Selective intraportal hepatocyte transplantation in analbuminemic and gunn rats. Transplantation 1993; 55(6): 1213.
12. Moscioni AD, Chowdhury JR, Barbour R, et al. Human liver cell transplantation: Prolonged function in athymic-gunn and athymic-analbuminemic hybrid rats. Gastroenterology 1989; 96: 1546.
13. Groth CG, Arborgh B, Bjorken C, et al. Correction of hyperbilirubinemia in the glucuronyltransferase-deficient rat by intraportal hepatocyte transplantation. Transplant Proc 1977; 9: 313.
14. Mito M, Kusano M, Sawa M. Hepatocyte transplantation for hepatic failure. Transplant Rev 1993; 7(10): 35.
15. Takeshita K, Ishibashi H, Suzuki M, Kodama M. Hepatocellular transplantation for metabolic support in experimental acute ischemic liver failure in rats. Cell Transplant 1993; 2: 319.
16. Sutherland DER, Minoru N, Matas AJ, et al. Hepatocellular transplantation in acute liver failure. Surgery 1977; 82: 124.
17. Sommer BG, Sutherland DER, Matas AJ, Simmons RL, Najarian JS. Hepatocellular transplantation for treatment of d-galactosamine-induced acute liver failure in rats. Transplant Proc 1979; 9(1): 578.
18. Demetriou AA, Reisner A, Sanchez J, Levenson SM, Moscioni AD, Chowdhury JR. Transplantation of microcarrier-attached hepatocytes into 90% partially hepatectomized rats. Hepatology 1988; 8(5): 1006.
19. Mito M, Kusano M. Hepatocyte transplantation in man. Cell Transplant 1993; 2: 65.
20. Grossman M, Raper SE, Kozarsky K, et al. Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolemia. Nat Genet 1994; 6: 335.
21. Habibullah CM, Syed IH, Qamar A, Taher-Uz Z. Human fetal hepatocyte transplantation in patients with fulminant hepatic failure. Transplantation 1994; 58: 951.
22. Mito M, Ebata H, Kusan M, et al. Studies on ectopic liver utilizing hepatocyte transplantation into the rat spleen. Transplant Proc 1979; 11(1): 585.
23. Gupta S, Aragona E, Vemuru RP, Bhargava KK, Burk RD, Chowdhury JR. Permanent engraftment and function of hepatocytes delivered to the liver: implications for gene therapy and liver repopulation. Hepatology 1991; 14: 144.
24. Mito M, Ebata H, Kusano M, Onishi T, Saito T, Sakamoto S. Morphology and function of isolated hepatocytes transplanted into rat spleen. Transplantation 1979; 28: 499.
25. Ponder KP, Gupta S, Leland F, et al. Mouse hepatocytes migrate to liver parenchyma and function indefinitely after intrasplenic transplantation. Proc Natl Acad Sci USA 1991; 88: 1217.
26. Ascher NL. Hepatocyte transplantation. Liver Transplant Surg 1995; 1: 139.
27. Qian S, Demetris AJ, Murase N, Rao AS, Fung JJ, Starzl TE. Murine liver allograft transplantation: tolerance and donor cell chimerism. Hepatology 1994; 19: 916.
28. Kamada N. The immunology of experimental liver transplantation in the rat. Immunology 1985; 55: 369.
29. Kamada N. Transplantation tolerance and immunosuppression following liver grafting in rats. Immunol Today 1985; 6(11): 336.
30. Knoop M, Pratt JR, Hutchinson IV. Evidence of alloreactive T suppressor cells in the maintenance phase of spontaneous tolerance after orthotopic liver transplantation in the rat. Transplantation 1994; 57: 1512.
31. Kamada N, Sumimoto R, Baguerizo A, Yoshimatsu A, Teramoto K, Yamaguchi A. Mechanisms of transplantation tolerance induced by liver grafting in rats: involvement of serum factors in clonal deletion. Immunology 1988; 64: 315.
32. Zimmermann FA, Butcher GW, Davies HS, Brons G, Kamada N, Turel O. Techniques for orthotopic liver transplantation in the rat and some studies of the immunologic responses to fully allogeneic liver grafts. Transplant Proc 1979; 11: 571.
33. Nakano H, Nakajima Y, Segawa M, et al. Immunologic significance of hepatocytes in tolerance induction after liver transplantation. Transplant Proc 1987; 14(1): 511.
34. Qian S, Fung JJ, Sun H, Demetris AJ, Starzl TE. Transplantation unresponsiveness induced by liver allografts in mouse strain with various histocompatibility disparities. Transpl Proc 1992; 24(4): 1605.
35. Foster S, Cranston D, Wood KJ, Morris PJ. Production of indefinite renal allograft survival in the rat by pretreatment with viable and nonviable hepatocytes or liver membrane extracts. Transplantation 1988; 45(1): 228.
36. Baumgartner D, LaPlante-O'Neill PM, Sutherland DER, Najarian JS. Effects of intrasplenic injection of hepatocytes, hepatocyte fragments and hepatocyte culture supernatants on D-galactosamine-induced liver failure in rats. Eur Surg Res 1983; 15: 129.
37. Gupta S, Chowdhury NR, Jagtiani R, et al. A novel system for transplantation of isolated hepatocytes utilizing HBsAg-producing transgenic donor cells. Transplantation 1990; 50(3): 472.
38. Hogan B, Constantini F, Lacy E. Manipulating the mouse embryo: a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1986.
39. Seglen PO. Preparation of rat liver parenchymal cells: enzymatic requirements for tissue dispersion. Exp Cell Res. 1973; 82: 391.
40. Seglen PO. Preparation of isolated rat liver cells. Methods Cell Biol 1976; 13: 29.
41. Sifers RN, Carlson JA, Clift SM, DeMayo FJ, Bullock DW, Woo SLC. Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice. Nucleic Acids Res 1987; 15(4): 1459.
42. Bumgardner GL, Li J, Heininger M, Ferguson RM, Orosz CG. In vivo immunogenicity of purified allogeneic hepatocytes in a murine hepatocyte transplant model. Transplantation 1998; 65: 47.
43. Bumgardner GL, Chen S, Almond PS, Ascher NL, Payne WD, Matas AJ. Role of macrophages in the immune response to hepatocytes. J Surg Res 1990; 48: 568.
44. Vemuru RP, Davidson A, Aragona E, Chowdhury JR, Burk RD, Gupta S. Immune tolerance to a defined heterologous antigen after intrasplenic hepatocyte transplantation: implications for gene therapy. FASEB J 1992; 6: 2836.