-
1
-
-
0028232498
-
Involvement of cytochrome P450 3A enzyme family in the major metabolic pathways of toremifene in human liver microsomes
-
Berthou F, Dreano Y, Belloc C, Kangas L, Gautier J-C and Beaune P (1994) Involvement of cytochrome P450 3A enzyme family in the major metabolic pathways of toremifene in human liver microsomes. Biochem Pharmacol 47:1883-1895.
-
(1994)
Biochem Pharmacol
, vol.47
, pp. 1883-1895
-
-
Berthou, F.1
Dreano, Y.2
Belloc, C.3
Kangas, L.4
Gautier, J.-C.5
Beaune, P.6
-
2
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
3
-
-
0029102061
-
7-HETE, 10-HETE, and 13-HETE are major products of liver microsomes in rat liver microsomes: Analysis of their stereochemistry, and the stereochemistry of their acid-catalyzed rearrangement
-
Brash AR, Boeglin WE, Capdevila JH, Yeola S and Blair IA (1995) 7-HETE, 10-HETE, and 13-HETE are major products of liver microsomes in rat liver microsomes: Analysis of their stereochemistry, and the stereochemistry of their acid-catalyzed rearrangement. Arch Biochem Biophys 321:485-492.
-
(1995)
Arch Biochem Biophys
, vol.321
, pp. 485-492
-
-
Brash, A.R.1
Boeglin, W.E.2
Capdevila, J.H.3
Yeola, S.4
Blair, I.A.5
-
4
-
-
0022357068
-
Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between different induced cytochromes P-450
-
Burke MD, Thompson S, Elcombe CR, Halpert J, Haaparanta T and Mayer RT (1985) Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between different induced cytochromes P-450. Biochem Pharmacol 34:3337-3345.
-
(1985)
Biochem Pharmacol
, vol.34
, pp. 3337-3345
-
-
Burke, M.D.1
Thompson, S.2
Elcombe, C.R.3
Halpert, J.4
Haaparanta, T.5
Mayer, R.T.6
-
5
-
-
0029787503
-
The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3
-
Capdevila JH, Wei S, Helvig C, Falck JR, Belosludtsev Y, Truan G, Graham-Lorence SE and Peterson JA (1996) The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3. J Biol Chem 271:22663-22671.
-
(1996)
J Biol Chem
, vol.271
, pp. 22663-22671
-
-
Capdevila, J.H.1
Wei, S.2
Helvig, C.3
Falck, J.R.4
Belosludtsev, Y.5
Truan, G.6
Graham-Lorence, S.E.7
Peterson, J.A.8
-
6
-
-
0002595605
-
Cytochrome P450 and the metabolism of arachidonic acid and oxygenated eicosanoids
-
(Ortiz de Montellano PR, ed) Plenum Press, New York
-
Capdevila JH, Zeldin D, Makita K, Karara A and Falck JR (1995) Cytochrome P450 and the metabolism of arachidonic acid and oxygenated eicosanoids, in Cytochrome P450: Structure, Mechanism, and Biochemistry, 2nd ed (Ortiz de Montellano PR, ed) pp 443-471, Plenum Press, New York.
-
(1995)
Cytochrome P450: Structure, Mechanism, and Biochemistry, 2nd Ed
, pp. 443-471
-
-
Capdevila, J.H.1
Zeldin, D.2
Makita, K.3
Karara, A.4
Falck, J.R.5
-
7
-
-
0031570357
-
Microtiter plate assays for inhibition of human, drug metabolizing cytochromes P450
-
Crespi CL, Miller VP and Penman BW (1997) Microtiter plate assays for inhibition of human, drug metabolizing cytochromes P450. Anal Biochem 248:188-190.
-
(1997)
Anal Biochem
, vol.248
, pp. 188-190
-
-
Crespi, C.L.1
Miller, V.P.2
Penman, B.W.3
-
8
-
-
0027940480
-
Regio- and stereoselective epoxidation of arachidonic acid by human cytochromes P450 2C8 and 2C9
-
Daikh BE, Lasker JM, Raucy JL and Koop DR (1994) Regio- and stereoselective epoxidation of arachidonic acid by human cytochromes P450 2C8 and 2C9. J Pharmacol Exp Ther 271:1427-1433.
-
(1994)
J Pharmacol Exp Ther
, vol.271
, pp. 1427-1433
-
-
Daikh, B.E.1
Lasker, J.M.2
Raucy, J.L.3
Koop, D.R.4
-
9
-
-
0026324036
-
Induction protocols for cytochromes P450IIIA in vivo and in primary cultures of animal and human hepatocytes
-
Daujat M, Pichard L, Fabre I, Pineau T, Fabre G, Bonfils C and Maurel P (1991) Induction protocols for cytochromes P450IIIA in vivo and in primary cultures of animal and human hepatocytes. Methods Enzymol 206:345-353.
-
(1991)
Methods Enzymol
, vol.206
, pp. 345-353
-
-
Daujat, M.1
Pichard, L.2
Fabre, I.3
Pineau, T.4
Fabre, G.5
Bonfils, C.6
Maurel, P.7
-
10
-
-
0029118476
-
Xenobiotic-inducible transcription of cytochrome P450 genes
-
Denison MS and Whitlock JP (1995) Xenobiotic-inducible transcription of cytochrome P450 genes. J Biol Chem 270:18175-18178.
-
(1995)
J Biol Chem
, vol.270
, pp. 18175-18178
-
-
Denison, M.S.1
Whitlock, J.P.2
-
11
-
-
0025311693
-
Cytochrome P-450-dependent oxidation of arachidonic acid to 16-, 17-, and 18-hydroxyeicosatetraenoic acids
-
Falck JR, Lumin S, Blair I, Dishman E, Martin MV, Waxman DJ, Guengerich FP and Capdevila JH (1990) Cytochrome P-450-dependent oxidation of arachidonic acid to 16-, 17-, and 18-hydroxyeicosatetraenoic acids. J Biol Chem 265:10244-10249.
-
(1990)
J Biol Chem
, vol.265
, pp. 10244-10249
-
-
Falck, J.R.1
Lumin, S.2
Blair, I.3
Dishman, E.4
Martin, M.V.5
Waxman, D.J.6
Guengerich, F.P.7
Capdevila, J.H.8
-
12
-
-
0028590127
-
Biochemistry and molecular biology of the human CYP2C subfamily
-
Goldstein JA and de Morais SMF (1994) Biochemistry and molecular biology of the human CYP2C subfamily. Pharmacogenetics 4:285-299.
-
(1994)
Pharmacogenetics
, vol.4
, pp. 285-299
-
-
Goldstein, J.A.1
De Morais, S.M.F.2
-
13
-
-
0000381290
-
Cytochromes P-450 of human liver: Classification and activity profile of the major enzymes
-
(Pacifici GM and Fracchia GN) Official Productions of the European Communities, Brussels
-
Guengerich FP (1995) Cytochromes P-450 of human liver: Classification and activity profile of the major enzymes, in Advances in Drug Metabolism in Man (Pacifici GM and Fracchia GN) pp 179-231, Official Productions of the European Communities, Brussels.
-
(1995)
Advances in Drug Metabolism in Man
, pp. 179-231
-
-
Guengerich, F.P.1
-
14
-
-
0026642570
-
Linoleic acid metabolism in the red alga lithothamnion corallioides: Biosynthesis of 11(R)-hydroxy-9(Z)-octadecadienoic acid
-
Hamberg M, Gerwick WH and Åsén PA (1992) Linoleic acid metabolism in the red alga lithothamnion corallioides: Biosynthesis of 11(R)-hydroxy-9(Z)-octadecadienoic acid. Lipids 27:487-493.
-
(1992)
Lipids
, vol.27
, pp. 487-493
-
-
Hamberg, M.1
Gerwick, W.H.2
Åsén, P.A.3
-
15
-
-
0028888384
-
Fetus-specific CYP3A7 and adult-specific CYP3A4 expressed in Chinese hamster CHL cells have similar capacity to activate carcinogenic mycotoxins
-
Hashimoto H, Nakagawa T, Yokoi T, Sawada M, Itoh S and Kamataki T (1995) Fetus-specific CYP3A7 and adult-specific CYP3A4 expressed in Chinese hamster CHL cells have similar capacity to activate carcinogenic mycotoxins. Cancer Res 55:787-791.
-
(1995)
Cancer Res
, vol.55
, pp. 787-791
-
-
Hashimoto, H.1
Nakagawa, T.2
Yokoi, T.3
Sawada, M.4
Itoh, S.5
Kamataki, T.6
-
16
-
-
0030586792
-
Dexamethasone induces bisallylic hydroxylation of polyunsaturated fatty acids by rat liver microsomes
-
Hörnsten L, Bylund J and Oliw EH (1996) Dexamethasone induces bisallylic hydroxylation of polyunsaturated fatty acids by rat liver microsomes. Arch Biochem Biophys 332:261-268.
-
(1996)
Arch Biochem Biophys
, vol.332
, pp. 261-268
-
-
Hörnsten, L.1
Bylund, J.2
Oliw, E.H.3
-
17
-
-
0026654417
-
Role of phospholipids in reconstituted cytochrome P450 3A form and mechanism of their activation of catalytic activity
-
Imaoka S, Imai Y, Shimada T and Funae Y (1992) Role of phospholipids in reconstituted cytochrome P450 3A form and mechanism of their activation of catalytic activity. Biochemistry 31:6063-6069.
-
(1992)
Biochemistry
, vol.31
, pp. 6063-6069
-
-
Imaoka, S.1
Imai, Y.2
Shimada, T.3
Funae, Y.4
-
18
-
-
0027143654
-
cDNA cloning and caracterization of a novel member of steroid-induced cytochrome P450 3A in rats
-
Kirita S and Matsubara T (1993) cDNA cloning and caracterization of a novel member of steroid-induced cytochrome P450 3A in rats. Arch Biochem Biophys 307:253-258.
-
(1993)
Arch Biochem Biophys
, vol.307
, pp. 253-258
-
-
Kirita, S.1
Matsubara, T.2
-
19
-
-
0028015588
-
Major glucocorticoid-inducible P450 in rat liver is not P450 3A1
-
Komori M and Oda Y (1994) Major glucocorticoid-inducible P450 in rat liver is not P450 3A1. J Biochem 116:114-120.
-
(1994)
J Biochem
, vol.116
, pp. 114-120
-
-
Komori, M.1
Oda, Y.2
-
20
-
-
0027164207
-
Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1
-
Laethem RM, Balazy M, Falck JR, Laethem CL and Koop DR (1993) Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1. J Biol Chem 268:12912-12918.
-
(1993)
J Biol Chem
, vol.268
, pp. 12912-12918
-
-
Laethem, R.M.1
Balazy, M.2
Falck, J.R.3
Laethem, C.L.4
Koop, D.R.5
-
21
-
-
0029100876
-
Phenobarbital induction of CYP2B1, CYP2B2, and CYP3A1 in rat liver: Genetic differences in a common regulatory mechanism
-
Larsen MC and Jefcoate CR (1995) Phenobarbital induction of CYP2B1, CYP2B2, and CYP3A1 in rat liver: Genetic differences in a common regulatory mechanism. Arch Biochem Biophys 321:467-476.
-
(1995)
Arch Biochem Biophys
, vol.321
, pp. 467-476
-
-
Larsen, M.C.1
Jefcoate, C.R.2
-
22
-
-
0027264432
-
Cytochrome P450TB (CYP2C): A major monooxygenase catalysing diclofenac 4′-hydroxylation in human liver
-
Leemann T, Transon C and Dayer P (1992) Cytochrome P450TB (CYP2C): A major monooxygenase catalysing diclofenac 4′-hydroxylation in human liver. Life Sci 52:29-34.
-
(1992)
Life Sci
, vol.52
, pp. 29-34
-
-
Leemann, T.1
Transon, C.2
Dayer, P.3
-
23
-
-
0030973315
-
+ channels in coronary smooth muscle through a quanine nucleotide binding protein
-
+ channels in coronary smooth muscle through a quanine nucleotide binding protein. Circ Res 80:877-884.
-
(1997)
Circ Res
, vol.80
, pp. 877-884
-
-
Li, P.L.1
Campbell, W.B.2
-
24
-
-
0025780578
-
Cytochrome P450 metabolism of arachidonic acid
-
McGiff JC (1991) Cytochrome P450 metabolism of arachidonic acid. Annu Rev Pharmacol Toxicol 31:339-369.
-
(1991)
Annu Rev Pharmacol Toxicol
, vol.31
, pp. 339-369
-
-
McGiff, J.C.1
-
25
-
-
9044254525
-
P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
-
Nelson DR, Koymans L, Kamataki T, Stegeman JJ, Feyereisen R, Waxman DJ, Waterman MR, Gotoh O, Coon MJ, Estabrook RW, Gunsalus IC and Nebert DW (1996) P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics 6:1-42.
-
(1996)
Pharmacogenetics
, vol.6
, pp. 1-42
-
-
Nelson, D.R.1
Koymans, L.2
Kamataki, T.3
Stegeman, J.J.4
Feyereisen, R.5
Waxman, D.J.6
Waterman, M.R.7
Gotoh, O.8
Coon, M.J.9
Estabrook, R.W.10
Gunsalus, I.C.11
Nebert, D.W.12
-
26
-
-
0028858960
-
Cytochrome P450 inhibitors: Evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes
-
Newton DJ, Wang RW and Lu AYH (1995) Cytochrome P450 inhibitors: Evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes. Drug Metab Dispos 23:154-158.
-
(1995)
Drug Metab Dispos
, vol.23
, pp. 154-158
-
-
Newton, D.J.1
Wang, R.W.2
Lu, A.Y.H.3
-
27
-
-
0024473078
-
Biosynthesis of 18(R)-hydroxyeicosatetraenoic acid from arachidonic acid by microsomes of monkey seminal vesicles: Some properties of a novel fatty acid omega 3-hydroxylase and omega 3-epoxygenase
-
1989
-
Oliw EH (1989) Biosynthesis of 18(R)-hydroxyeicosatetraenoic acid from arachidonic acid by microsomes of monkey seminal vesicles: Some properties of a novel fatty acid omega 3-hydroxylase and omega 3-epoxygenase. J Biol Chem 264:17845-17853, 1989.
-
(1989)
J Biol Chem
, vol.264
, pp. 17845-17853
-
-
Oliw, E.H.1
-
28
-
-
0027394892
-
Bis-Allylic hydroxylation of linoleic acid and arachidonic acid by human hepatic monooxygenases
-
Oliw EH (1993) bis-Allylic hydroxylation of linoleic acid and arachidonic acid by human hepatic monooxygenases. Biochim Biophys Acta 1166:258-263.
-
(1993)
Biochim Biophys Acta
, vol.1166
, pp. 258-263
-
-
Oliw, E.H.1
-
29
-
-
0028335991
-
Oxygenation of polyunsaturated fatty acids by cytochrome P450 monooxygenase
-
Oliw EH (1994) Oxygenation of polyunsaturated fatty acids by cytochrome P450 monooxygenase. Prog Lipid Res 33:329-354.
-
(1994)
Prog Lipid Res
, vol.33
, pp. 329-354
-
-
Oliw, E.H.1
-
30
-
-
0027216936
-
Bis-Allylic hydroxylation of polyunsaturated fatty acids by hepatic monooxygenases and its relation to the enzymatic and nonenzymatic formation of conjugated hydroxy fatty acids
-
Oliw EH, Brodowsky ID, Hörnsten L and Hamberg M (1993) bis-Allylic hydroxylation of polyunsaturated fatty acids by hepatic monooxygenases and its relation to the enzymatic and nonenzymatic formation of conjugated hydroxy fatty acids. Arch Biochem Biophys 300:434-439.
-
(1993)
Arch Biochem Biophys
, vol.300
, pp. 434-439
-
-
Oliw, E.H.1
Brodowsky, I.D.2
Hörnsten, L.3
Hamberg, M.4
-
31
-
-
0029817648
-
Bisallylic hydroxylation and epoxidation of polyunsaturated fatty acids by cytochrome P450
-
Oliw EH, Bylund J and Herman C (1996) Bisallylic hydroxylation and epoxidation of polyunsaturated fatty acids by cytochrome P450. Lipids 31:1003-1021.
-
(1996)
Lipids
, vol.31
, pp. 1003-1021
-
-
Oliw, E.H.1
Bylund, J.2
Herman, C.3
-
32
-
-
0030056594
-
Specificity of substrate and inhibitor probes for cytochrome P450s: Evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes
-
Ono S, Hatanaka T, Hotta H, Satoh T, Gonzales FJ and Tsutsui M (1996) Specificity of substrate and inhibitor probes for cytochrome P450s: Evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes. Xenobiotica 26:681-693.
-
(1996)
Xenobiotica
, vol.26
, pp. 681-693
-
-
Ono, S.1
Hatanaka, T.2
Hotta, H.3
Satoh, T.4
Gonzales, F.J.5
Tsutsui, M.6
-
33
-
-
0002751786
-
Oxygenation activation and reactivity
-
(Ortiz de Montellano PR, ed) Plenum Press, New York
-
Ortiz de Montellano KR (1995) Oxygenation activation and reactivity, in Cytochrome P450: Structure, Mechanism, and Biochemistry, 2nd ed (Ortiz de Montellano PR, ed) pp 245-303, Plenum Press, New York.
-
(1995)
Cytochrome P450: Structure, Mechanism, and Biochemistry, 2nd Ed
, pp. 245-303
-
-
Ortiz De Montellano, K.R.1
-
34
-
-
0028918373
-
Differential regulation of the cytochrome P450 3A1 gene transcription by dexamethasone in immature and adult rat liver
-
Pereira TM and Lechner MC (1995) Differential regulation of the cytochrome P450 3A1 gene transcription by dexamethasone in immature and adult rat liver. Eur J Biochem 229:171-177.
-
(1995)
Eur J Biochem
, vol.229
, pp. 171-177
-
-
Pereira, T.M.1
Lechner, M.C.2
-
35
-
-
0028959042
-
Mechanisms of free radical oxidation of unsaturated lipids
-
Porter NA, Caldwell SE and Mills KA (1995) Mechanisms of free radical oxidation of unsaturated lipids. Lipids 30:277-290.
-
(1995)
Lipids
, vol.30
, pp. 277-290
-
-
Porter, N.A.1
Caldwell, S.E.2
Mills, K.A.3
-
36
-
-
0030889716
-
The role of cytochrome P450-dependent metabolites of arachidonic acid in blood pressure regulation and renal function: A review
-
Rahman M, Wright JT and Douglas JG (1997) The role of cytochrome P450-dependent metabolites of arachidonic acid in blood pressure regulation and renal function: A review. Am J Hypertens 10:356-365.
-
(1997)
Am J Hypertens
, vol.10
, pp. 356-365
-
-
Rahman, M.1
Wright, J.T.2
Douglas, J.G.3
-
37
-
-
0029039791
-
Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1, and 1A2: Regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomes
-
Rifkind AB, Lee C, Chang TKH and Waxman DJ (1995) Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1, and 1A2: Regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomes. Arch Biochem Biophys 320:380-389.
-
(1995)
Arch Biochem Biophys
, vol.320
, pp. 380-389
-
-
Rifkind, A.B.1
Lee, C.2
Chang, T.K.H.3
Waxman, D.J.4
-
38
-
-
0023949862
-
Modulation of rabbit and human hepatic cytochrome P-450-catalyzed hydroxylations by α-naphthoflavone
-
Schwab GE, Raucy JL and Johnson EF (1988) Modulation of rabbit and human hepatic cytochrome P-450-catalyzed hydroxylations by α-naphthoflavone. Mol Pharmacol 33:493-499.
-
(1988)
Mol Pharmacol
, vol.33
, pp. 493-499
-
-
Schwab, G.E.1
Raucy, J.L.2
Johnson, E.F.3
-
39
-
-
0026808682
-
Identification of the pharmacogenetic determinants of alfentanil metabolism: Cytochrome P-450 3A4
-
Yun CH, Wood M, Wood AJ and Guengerich FP (1992) Identification of the pharmacogenetic determinants of alfentanil metabolism: Cytochrome P-450 3A4, Anesthesiology 77:467-474.
-
(1992)
Anesthesiology
, vol.77
, pp. 467-474
-
-
Yun, C.H.1
Wood, M.2
Wood, A.J.3
Guengerich, F.P.4
-
40
-
-
0029122098
-
Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform
-
Zeldin DC, DuBois RN, Falck JR and Capdevila JH (1995) Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform. Arch Biochem Biophys 322:76-86.
-
(1995)
Arch Biochem Biophys
, vol.322
, pp. 76-86
-
-
Zeldin, D.C.1
DuBois, R.N.2
Falck, J.R.3
Capdevila, J.H.4
|