Mutations of K-ras oncogene in human adrenal tumours in Taiwan

British Journal of Cancer

Volumn 77, Issue 7, 1998, Pages 1060-1065

  Lin, S R ^a   Tsai, J H ^a   Yang, Y C ^a   Lee, S C ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Adrenal tumour; K ras; Mutation; Taiwan

Indexed keywords

ADRENAL TUMOR; ARTICLE; CLINICAL ARTICLE; CUSHING DISEASE; CUSHING SYNDROME; EXON; FEMALE; GENE MUTATION; HUMAN; MALE; ONCOGENE K RAS; PRIMARY HYPERALDOSTERONISM; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; THYROID TUMOR;

EID: 0031950982     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1998.177     Document Type: Article

References (27)

1. Barbacid M (1987) ras genes. Ann Rev Biochem 56: 779-827
2. Barbacid M (1990) ras oncogenes: their role in neoplasm. Eur J Clin Invest 20: 225-235
3. Bos JL (1989) Ras oncogenes in human cancer: a review. Cancer Res 49: 4682
4. Cantley LC, Auger KR, Carpenter C, Duckworth B, Graziani A, Kapeller R and Soltoff S (1991) Oncogenes and signal transduction. Cell 64: 281-302
5. Capon DJ, Seeburg PH, McGrath JP, Hayflick JS, Edman U, Levinson AD and Goeddel DV (1983) Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations. Nature 304: 507-513
6. Der CJ, Frinkel T and Copper GM (1986) Biological and biochemical of human rasK genes mutated at codon 61. Cell 44: 167-176
7. Eng C, Smith DP, Mulligan LM, Healey CS, Zvelebil MJ, Stonehouse TJ, Ponder MA, Jackson CEJ, Walderfield MD and Ponder BAJ (1995) A novel point mutation in the tyrosine kinase domain of the ret proto-oncogene in sporadic medullary thyroid carcinoma and in a family with FMTC. Oncogene 10: 509-513
8. George DL, Scott AF, de Martinville B and Francke U (1984) Amplified DNA in Y1 mouse adrenal tumor cells: isolation of cDNAs complementary to an amplified c-ki-ras gene and localization of homologous sequences to mouse chromosome 6. Nucleic Acids Res 12: 2731
9. George DL, Scott AF, Trusko S, Glick B, Ford E and Dorney DJ (1985) Structure and expression of amplified c-ki-ras gene sequence in Y1 mouse adrenal cells. EMBO J 4: 1199
10. Gibbs JB, Sigal IS and Scolnick EM (1985) Biochemical properties of normal and oncogenic ras p21. Trends Biochem Sci 10: 350-353
11. Hall A (1990) The cellular functions of small GTP-binding proteins. Science 249: 635-639
12. Knudson AG (1989) Genetics of human cancer. Annu Rev Genet 20: 231-251
13. Landis CA, Masters SB, Spada A, Pace AM, Bourine HR and Vallar L (1989) GTPase inhibiting mutations activate the α chain of Gs and stimulate adenylyl cyclase in human pituitary tumors. Nature 340: 629-696
14. Lemoine NR, Mayall ES, Wyllie FW, Williams ED, Goyns M, Stringer B and Wynford-Thomas D (1989) High frequency of ras oncogene activation in all stages of human thyroid tumorigenesis. Oncogene 4: 159-164
15. Lin SR, Lee YJ and Tasi JH (1994) Mutations of the p53 gene in human functional adrenal neoplasms. J Clin Endocr Metab 78: 483-491
16. Lin SR, Yang YC, Jung JH and Tsai JH (1996) A significant decrease of the transcriptional activity of p53 mutants deriving from human functional adrenal tumors. DNA Cell Biol 15: 793-803
17. Lyons J, Landis AC, Harsh G, Vallar L, Grunewald K, Feichtinger H, Duch Q, Clark OH, Kawasaki E, Bourine HR and McCormick F (1990) Two G protein oncogenes in human endocrine tumors. Science 249: 655-658
18. Mark J (1989) Many gene changes found in cancer. Science 264: 1386-1388
19. Mikaaaako S, Junko F-y, Yutaka I, Hiroshi K, Susumn N and Shigeyuki Y (1992) A glutamic acid residue at codon 31 of ras protein is essential to the signal transduction for neurite outgrowth of PC 12 cells and the stimulation of GTPase activity by GTPras. Oncogene 7: 475-480
20. Moley JF, Brother MB, Wells SA, Spengler BA, Biedler JL and Brodeur GM (1991) Low frequency of ras gene mutations in neuro-blastoma, pheochromocytoma, and medullary thyroid cancers. Cancer Res 51: 1596-1599
21. Moul JT, Theune SM and Chang EM (1993) Abset ras gene mutations in human adrenal cortical neoplasms and pheochromocytomas. J Urol 149: 1389-1394
22. Powers S, O'Neill K and Wigler M (1989) Dominant yeast and mammalian RAS mutations that interfere with the the CD23-dependent activation of wild-type RAS in Saccharomyces cerevisiae. Mol Cell Biol 9(2): 390-395
23. Sambrook J, Fritsch EF and Maniatis T (1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Nolan C (ed.), pp 6.22-6.34
24. Schwab M, Alitalo K, Varmus HE, Bishop JM and George D (1983) A cellular oncogene (c-ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumor cells. Nature 303: 497-501
25. Ras. Oncogene 7: 475-480
26. Sigal IS, Gibbs JB, D'Alonzo JS, Temeles GL, Wolanske BS, Socher SH and Scolnick EM (1986) Mutant ras-encoded proteins with altered nucleotide binding exert domain biological effects. Proc Natl Acad Sci USA 83: 952-956
27. Vogel US, Dixon RAF, Schaber MD, Diehl RE, Marshall MS, Scolnick EM, Sigal IS and Gibbs JB (1988) Cloning of bovine GAP and its interaction with oncogenic ras p21. Nature 335: 90-93