Combination of LC-MS and LC-NMR as a tool for the structure determination of natural products

Journal of Natural Products

Volumn 61, Issue 2, 1998, Pages 175-178

  Vogler, B ^a   Klaiber, I ^a   Roos, G ^a   Walter, C U ^a   Hiller, W ^b   Sandor, P ^b   Kraus, W ^a  

^a UNIVERSITY OF HOHENHEIM   (Germany)

^b Varian GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; SESQUITERPENE LACTONE DERIVATIVE;

ARTICLE; DRUG IDENTIFICATION; DRUG SCREENING; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEAR OVERHAUSER EFFECT; PHYTOCHEMISTRY; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0031950977     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np970416z     Document Type: Article

References (11)

1. Gu, Z.-M.; Zhaou, D.; Wu, J.; Shi, G.; Zeng, L.; McLaughlin, J. L. J. Nat. Prod. 1997, 60, 242-248 and references therein.
2. Smallcombe, S. H.; Patt, S. L.; Keifer, P. A. J. Mag. Reson., Ser. A 1995, 117, 295-303.
3. Albert, K. J. Chromatogr., A 1995, 703, 123-147.
4. Spring, O.; Buschmann, H.; Vogler, B.; Schilling, E. E.; Spraul, M.; Hoffmann, M. Phytochemistry 1995, 39, 609-612.
5. Spring, O.; Heil, N.; Vogler, B. Phytochemistry 1997, 46, 1369-1373.
6. Roos, G.; Naturstoffe aus Butea monosperma (Fabaceae), Vernonia fastigiata (Asteraceae) und Thamnosma africana (Rutaceae) mit anthelminthischer, nematizider und antibakterieller Wirkung (Natural products from Butea monosperma (Fabaceae), Vernonia fastigata (Asteraceae) and Thamnosma africana (Rutaceae) with anthelmintic, nematicidal and antibacterial activities). Dissertation, Universität Hohenheim, 1997, pp 34-62; Shaker Verlag: Aachen, 1998; ISBN 3-8265-3298-8.
7. LC-MS spectra were recorded on a Finnigan TSQ 700 in the APCI mode.
8. LC-NMR spectra were recorded on a Varian Unity Inova 500 MHz spectrometer equipped with a PFG-probe having a flow cell of 65 μL active volume.
9. The resonance of water changes with respect to the referenced acetonitrile signal.
10. Standard Varian Pulse Library.
11. Stott, K.; Keeler, J.; Van, Q. N.; Shaka, A. J. J. Magn. Reson. 1997, 125, 302-324.