Technetium-99m labeled to human immunoglobulin G through the nicotinyl hydrazine derivative: A clinical study

Journal of Nuclear Medicine

Volumn 39, Issue 1, 1998, Pages 119-124

  Dams, Els T M ^a   Oyen, Wim J G ^a   Boerman, Otto C ^a   Claessens, Roel A M J ^a   Wymenga, Ate B ^a   Van Der Meer, Jos W M ^a   Corstens, Frans H M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

HYNIC; Imaging; Immunoglobulin G; Infection; Inflammation

Indexed keywords

GLYCINE DERIVATIVE; IMMUNOGLOBULIN G; ISONIAZID DERIVATIVE; PENTETATE INDIUM IN 111; PERTECHNETIC ACID TC 99M; TECHNETIUM 99M; TIN DERIVATIVE; TRICINE; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; BONE INFECTION; CHRONIC OSTEOMYELITIS; CLINICAL ARTICLE; CLINICAL PROTOCOL; CLINICAL TRIAL; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG MIXTURE; FEMALE; GRAFT INFECTION; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; JOINT PROSTHESIS; MALE; MUSCULOSKELETAL SYSTEM INFLAMMATION; PRIORITY JOURNAL; RADIOISOTOPE DISTRIBUTION; SCINTIGRAPHY; SOFT TISSUE INFECTION; SPONDYLITIS;

BACTERIAL INFECTIONS; BONE DISEASES, INFECTIOUS; FEMALE; HUMANS; IMMUNOGLOBULIN G; INDIUM RADIOISOTOPES; INFLAMMATION; MALE; MIDDLE AGED; ORGANOTECHNETIUM COMPOUNDS; PENTETIC ACID; PROSPECTIVE STUDIES; PROSTHESIS-RELATED INFECTIONS; RADIOPHARMACEUTICALS; SENSITIVITY AND SPECIFICITY; SOFT TISSUE INFECTIONS;

EID: 0031950735     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Hoffer P. Gallium and infection. J Nucl Med 1980;21:484-488.
2. Staab EV, McCartney WH. Role of gallium-67 in inflammatory disease. Semin Nucl Med 1978;8:219-234.
3. McAfee JG, Thakur ML. Survey of radioactive agents for the in vitro labeling of phagocytic leukocytes. J Nucl Med 1976;17:480-492.
4. Segal AW, Arnot RN, Thakur ML, Lavender JP. Indium-111-labeled leukocytes for localisation of abscesses. Lancet 1976;ii:1056-1058.
5. Froelich JW, Swanson D. Imaging of inflammatory processes with labeled cells. Semin Nucl Med 1984;14:128-140.
6. Peters AM, Danpure HJ, Osman S, et al. Preliminary clinical experience with Tc-99m-HMPAO for labelling leucocytes and imaging infection. Lancet 1986;ii:945-949.
7. Vorne M, Soini I, Lantto T, Paakkinen S. Technetium-99m-HMPAO-labeled leukokytes in detection of inflammatory lesions: comparison with gallium-67-citrate. J Nucl Med 1989;30:1332-1336.
8. Perkins PJ. Early gallium-67 abdominal imaging: pitfalls due to bowel activity. Am J Roentgenol 1981;136:1016-1017.
9. 99mTc-labeled leukocytes, and polyclonal and monoclonal antibodies. Semin Nucl Med 1996;26:51-64.
10. Ebright JR, Soin JS, Manoli RS. The gallium scan. Problems and misuse in examination of patients with suspected infection. Arch Intern Med 1982;142:246-254.
11. Seabold JE, Nepola JV, Conrad GR, et al. Detection of osteomyelitis at fracture nonunion sites: comparison of two scintigraphic methods. Am J Roentgenol 1989;152: 1021-1027.
12. Bekerman C, Hoffer PB, Bitran JD. The role of gallium-67 in the clinical evaluation of cancer. Semin Nucl Med 1984;14:296-323.
13. Lange JMA, Boucher CAB, Hollak CEM, et al. Failure of zidovudine prophylaxis after accidental exposure to HIV-1. N Engl J Med 1990;322:1375-1377.
14. Rubin RH, Fischman AJ, Callahan RJ, et al. In-111-labeled nonspecific immunoglobulin scanning in the detection of focal infection. N Engl J Med 1989;321:935-940.
15. Serafini AN, Garty I, Vargas-Cuba R, et al. Clinical evaluation of a scintigraphic method for diagnosing inflammations/infections using indium-111-labeled nonspecific human IgG. J Nucl Med 1991;32:2227-2232.
16. Datz FL, Anderson CE, Ahluwalia R, et al. The efficacy of indium-111-polyclonal IgG for the detection of infection and inflammation. J Nucl Med 1994;35:74-83.
17. Khalkali I, Mena I, Rauh DA, Diggles LE, Pham HL, Mason GR. 111-Indium-DTPA-IgG lung imaging in patients with pulmonary and HIV infection. Chest 1995;107: 1336-1341.
18. Oyen WJG, Claessens RAMJ, Raemaekers JMM, de Pauw BE, van der Meer JWM, Corstens FHM. Diagnosing infection in febrile granulocytopenic patients with indium-111 labeled human IgG. J Clin Oncol 1992;10:61-68.
19. Fritzberg AR, Abrams PL, Beaumier PL, et al. Specific and stable labeling of antibodies with technetium-99m with a diamide dithiolate chelating agent. Proc Natl Acad Sci USA 1988;85:4025-4029.
20. Hnatowich DJ, Mardirossian G, Rusckowski M, Fogarasi M, Virzi F, Winnard P Jr. Directly and indirectly technetium-99m-labeled antibodies: a comparison of in vitro and animal in vivo properties. J Nucl Med 1993;34:109-119.
21. Oyen WJG, Claessens RAMJ, van der Meer JWM, Corstens FHM. Biodistribution and kinetics of radiolabeled proteins in rats with focal infection. J Nucl Med 1992;33:388-394.
22. Abrams MJ, Juweid M, ten Kate CI, et al. Technetium-99m-human polyclonal IgG radiolabeled via the hydrazino nicotinamide derivative for imaging focal sites of infection in rats. J Nucl Med 1990;31:2022-2028.
23. Claessens RAMJ, Boerman OC, Koenders EB, Oyen WJG, van der Meer JWM, Corstens FHM. Technetium-99m labelled hydrazinonicotinamido human non-specific polyclonal immunoglobulin G for detection of infectious foci: a comparison with two other technetium-labelled immunoglobulin preparations. Eur J Nucl Med 1996;23: 414-421.
24. Nijhof MW, Oyen WJG, van Kampen A, Claessens RAMJ, van der Meer JWM, Corstens FHM. Evaluation of infections of the locomotor system with indium-111-labeled human IgG scintigraphy. J Nucl Med 1997;38:1300-1305.
25. Oyen WJG, Claessens RAMJ, van der Meer JWM, Corstens FHM. Detection of subacute infectious foci with indium-111-labeled autologous leukocytes and with indium-111-labeled human nonspecific immunoglobulin G: a prospective comparative study. J Nucl Med 1991;32:1854-1860.
26. Arka A, Aktolun C, Gooden C, Epenetos A, Papadimitriou A. Tc-99m-labeled nonspecific polyclonal human immunoglobulin G is taken up by malignant tumors. Clin Nucl Med 1994;19:708-712.
27. Fischman AJ, Rubin RH, Khaw BA, et al. Detection of acute inflammation with In-111 labeled nonspecific polyclonal IgG. Semin Nucl Med 1988;18:335-344.
28. Callahan RJ, Barrow SA, Abrams MJ, Rubin RH, Fischman AJ. Biodistibution and dosimetry of technetium-99m-hydrazino nicotinamide IgG: comparison with indium-111-DTPA-IgG. J Nucl Med 1996;37:843-846.
29. Corstens FHM, Oyen WJG, Becker WS. Radioimmunoconjugates in the detection of infection and inflammation. Semin Nucl Med 1993;23:148-164.
30. Claessens RAMJ, Koenders EB, Oyen WJG, Corstens FHM. Retention of technetium-99m in infectious foci in rats after release from technetium-99m labelled human non-specific polyclonal immunoglobulin G: a dual study with hydrazinonicotinamido and iminothiolano immunoglobulin. Eur J Nucl Med 1996;23:1536-1539.
31. 99mTc [Abstract]. J Nucl Med Allied Sci 1989;33:286.
32. Hovi I, Taavitsainen M, Lantto T, Vorne M, Paul R, Remes K. Technetium-99m-HMPAO-labeled leukocytes and technetium-99m-labeled human polyclonal immunoglobulin G in diagnosis of focal purulent disease. J Nucl Med 1993;34:1428-1434.
33. 99mTc-human immunoglobulin (HIG): first results of a new agent for the localization of infection and inflammation. Eur J Nucl Med 1990;16:649-655.
34. Moretti JL, Rapin JR, Saccavini JC, Lageron A, Le Poncin M, Bardy A. 2,3-Dimercaptosuccinic acid chelates: their structure and biological behaviour. In: Raynaud C, ed. Proceedings of the Third World Congress of Nuclear Medicine and Biology. Paris: Nuclear Medicine and Biology; 1982:1651-1654.
35. Spinelli F, Milella M, Sara R, Banfi F, Possa M, Vigorelli R. The value of Tc-99m-labelled human immunoglobulin scan in the evaluation of Crohn's disease. Nucl Med 1990;27:274-278.
36. Amdt JW, van der Sluys-Veer A, Blok D, et al. A prospective comparison of Tc-99m-labeled polyclonal human immunoglobulin and In-111 granulocytes for localization of inflammatory bowel disease. Acta Radiol 1992;33:140-144.
37. 99mTc-labelling of hydrazino nicotinamide modified proteins [Abstract]. J Labelled Compd Rad 1994;35:1-2.