A new cytotoxic prenylhydroquinone from a mediterranean tunicate of the genus Aplydium

Natural Product Letters

Volumn 11, Issue 2, 1998, Pages 127-130

  Rueda, Ana ^a   Zubía, Eva ^a   Ortega, María J ^a   Salvá, Javier ^a  

^a UNIVERSITY OF CÁDIZ   (Spain)

Author keywords

Aplydium; Cytotoxicity; Prenylhydroquinone; Tunicate

Indexed keywords

BENZENE DERIVATIVE; HYDROQUINONE DERIVATIVE; PRENYLAMINE;

ANIMAL CELL; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; INVERTEBRATE; LEUKEMIA P 388; LYMPHOMA CELL LINE; MEDITERRANEAN SEA; MOUSE; NONHUMAN; SPECTROSCOPY; TUMOR CELL CULTURE; TUMOR CELL LINE;

EID: 0031950719     PISSN: 10575634     EISSN: None     Source Type: Journal    
DOI: 10.1080/10575639808041208     Document Type: Article

References (7)

1. D.J. Faulkner (1997) Nat. Prod. Rep., 14, 259-302 and previous reviews of this series.
2. W. Fenical (1976) Food-Drugs from the Sea Proceedings 1974, eds. (H.H. Webber and G.D. Ruggieri), Marine Technology Society, Washington D.C. p. 388.
3. B.M. Howard, K. Clarkson, and R.L. Bernstein (1979) Tetrahedron Lett., 4449-4452.
4. N.M. Targett and W.S. Keeran (1984) J. Nat. Prod., 47, 556-557.
5. E. Breitmeier and W. Voelter (1989) Carbon -13 NMR Spectroscopy. 3 rd Ed., VCH, New York, p. 192.
6. M.H.G. Munro, R.T. Luibrand, and J.W. Blunt (1987) Bioorganic Marine Chemistry, vol. 1, ed. (P.J. Scheuer), Springer-Verlag, Berlin, p 108.
7. - The hydroquinone 2 is readly oxidized to the corresponding quinone. This quinone was isolated from less polar fractions of the general chromatography due to the oxidation of 2 during the isolation process.