-
1
-
-
0002438263
-
Dimeric Cantaranthus alkaloids
-
Cassady JM, Douros JD, eds. New York: Academic Press
-
Gerzon K. Dimeric Cantaranthus alkaloids. In: Cassady JM, Douros JD, eds. Anticancer agents based on natural products models. New York: Academic Press 1980: 271-317.
-
(1980)
Anticancer Agents Based on Natural Products Models
, pp. 271-317
-
-
Gerzon, K.1
-
2
-
-
0004028961
-
-
Berlin: Springer-Verlag
-
Dustin P. Microtubules. Berlin: Springer-Verlag, 1984.
-
(1984)
Microtubules
-
-
Dustin, P.1
-
3
-
-
0021229643
-
Taxol: An antimitotic agent with a new mechanism of action
-
Manfredi JJ, Horwitz SB. Taxol: an antimitotic agent with a new mechanism of action. Pharmacol Ther 1984; 25: 83-125.
-
(1984)
Pharmacol Ther
, vol.25
, pp. 83-125
-
-
Manfredi, J.J.1
Horwitz, S.B.2
-
4
-
-
0028235678
-
Comparative effects of taxol and Taxotere on two different human carcinoma cell lines
-
Garcia P, Braguer D, Carles G, et al. Comparative effects of taxol and Taxotere on two different human carcinoma cell lines. Cancer Chemother Pharmacol 1994; 34: 335-43.
-
(1994)
Cancer Chemother Pharmacol
, vol.34
, pp. 335-343
-
-
Garcia, P.1
Braguer, D.2
Carles, G.3
-
5
-
-
0029360519
-
Microtubule dynamics taking aim at a moving target
-
Wilson L, Jordan MA. Microtubule dynamics taking aim at a moving target. Chem Biol 1995; 2: 569-73.
-
(1995)
Chem Biol
, vol.2
, pp. 569-573
-
-
Wilson, L.1
Jordan, M.A.2
-
6
-
-
0027196777
-
Taxol induces internucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cells
-
Bhalla K, Ibrado AM, Tourkina E, Tang C, Mahoney M, Huang Y. Taxol induces internucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cells. Leukemia 1993; 7: 563-8.
-
(1993)
Leukemia
, vol.7
, pp. 563-568
-
-
Bhalla, K.1
Ibrado, A.M.2
Tourkina, E.3
Tang, C.4
Mahoney, M.5
Huang, Y.6
-
7
-
-
0028983396
-
Paclitaxel (taxol) inhibits protein isopropylation and induces apoptosis in PC-3 human prostate cancer cells
-
Danesi R, Figg W, Reed E, Myers C. Paclitaxel (taxol) inhibits protein isopropylation and induces apoptosis in PC-3 human prostate cancer cells. Mol Pharmacol 1995; 47: 1106-11.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 1106-1111
-
-
Danesi, R.1
Figg, W.2
Reed, E.3
Myers, C.4
-
8
-
-
0025651121
-
Disruption of microtubules induces an endogenous suicide pathway in human leukemia HL-60 cells
-
Martin SJ, Cotter T. Disruption of microtubules induces an endogenous suicide pathway in human leukemia HL-60 cells. Cell Tissue Kinet 1990; 23: 545-59.
-
(1990)
Cell Tissue Kinet
, vol.23
, pp. 545-559
-
-
Martin, S.J.1
Cotter, T.2
-
9
-
-
0028875515
-
Microtubuleactivc drugs taxol, vinblastine and nocodazole increase the levels of transcriptionnally active p53
-
Tishler RB, Lamppu DM, Park S, Price B. Microtubuleactivc drugs taxol, vinblastine and nocodazole increase the levels of transcriptionnally active p53. Cancer Res 1995; 55: 6021-5.
-
(1995)
Cancer Res
, vol.55
, pp. 6021-6025
-
-
Tishler, R.B.1
Lamppu, D.M.2
Park, S.3
Price, B.4
-
10
-
-
0031584806
-
Pretreatment by tubulin agents decreases C-myc induction in human colon carcinoma cell line HT29-D4
-
El Khyari S, Bourgarel V, Barra Y, Braguer D, Briand C. Pretreatment by tubulin agents decreases C-myc induction in human colon carcinoma cell line HT29-D4. Biochem Biophys Res Commun 1997; 231: 751-5.
-
(1997)
Biochem Biophys Res Commun
, vol.231
, pp. 751-755
-
-
El Khyari, S.1
Bourgarel, V.2
Barra, Y.3
Braguer, D.4
Briand, C.5
-
12
-
-
0029964257
-
Taxol induces bcl-2 Phosphorylation and death of prostate cancer cells
-
Ilaldar S, Chintapalli J, Croce M. Taxol induces bcl-2 Phosphorylation and death of prostate cancer cells. Cancer Res 1996; 56: 1253-5.
-
(1996)
Cancer Res
, vol.56
, pp. 1253-1255
-
-
Ilaldar, S.1
Chintapalli, J.2
Croce, M.3
-
13
-
-
0030615086
-
Bcl-xL overexpression inhibits progression of molecular events leading to paclitaxel-induced apoptosis of human acute myeloid leukemia HL60 cells
-
Ibrado AM, Liu L, Bhalla K. Bcl-xL overexpression inhibits progression of molecular events leading to paclitaxel-induced apoptosis of human acute myeloid leukemia HL60 cells. Cancer Res 1997; 57: 1109-15.
-
(1997)
Cancer Res
, vol.57
, pp. 1109-1115
-
-
Ibrado, A.M.1
Liu, L.2
Bhalla, K.3
-
14
-
-
0028109983
-
BCL-2 expression in human colorectal adenomas and carcinomas
-
Hague A, Moorghen M, Hicks D, et al. BCL-2 expression in human colorectal adenomas and carcinomas. Oncogene 1994; 9: 3367-70.
-
(1994)
Oncogene
, vol.9
, pp. 3367-3370
-
-
Hague, A.1
Moorghen, M.2
Hicks, D.3
-
15
-
-
0028841187
-
Differentiation of neuroblastoma enhances Bcl-2 expression and induces alterations of apoptosis and drug resistance
-
Lasorella A, lavarone A, Israel MA. Differentiation of neuroblastoma enhances Bcl-2 expression and induces alterations of apoptosis and drug resistance. Cancer Res 1995; 55: 4711-6.
-
(1995)
Cancer Res
, vol.55
, pp. 4711-4716
-
-
Lasorella, A.1
Lavarone, A.2
Israel, M.A.3
-
16
-
-
0027382375
-
Taxol shares the ability of bacterial lipopolysaccharide to induce tyrosine phosphorylation of microtubule-associated protein kinase
-
Ding A, Sanchez E, Nathan CF. Taxol shares the ability of bacterial lipopolysaccharide to induce tyrosine phosphorylation of microtubule-associated protein kinase. J Immunol 1993; 151: 559-606.
-
(1993)
J Immunol
, vol.151
, pp. 559-606
-
-
Ding, A.1
Sanchez, E.2
Nathan, C.F.3
-
17
-
-
0028793720
-
Enhanced interaction between tubulin and microtubule-associated protein 2 via inhibition of MAP kinase and cdc2 kinase by paclitaxel
-
Nishio K, Arioka H, Ishida T. Enhanced interaction between tubulin and microtubule-associated protein 2 via inhibition of MAP kinase and cdc2 kinase by paclitaxel. Int J Cancer 1995; 63: 688-93.
-
(1995)
Int J Cancer
, vol.63
, pp. 688-693
-
-
Nishio, K.1
Arioka, H.2
Ishida, T.3
-
18
-
-
0026723301
-
Taxol: The first of the taxanes, an important new class of antitumor agents
-
Rowinsky EK, Onetto N, Canetta RA. Taxol: the first of the taxanes, an important new class of antitumor agents. Semin Oncol 1992; 19: 646-62.
-
(1992)
Semin Oncol
, vol.19
, pp. 646-662
-
-
Rowinsky, E.K.1
Onetto, N.2
Canetta, R.A.3
-
19
-
-
0029563590
-
Preclinical profiles of docetaxel (Taxotere): Efficacy as a single agent and in combination
-
Bissery MC, Vrignaud P, Lavelle F. Preclinical profiles of docetaxel (Taxotere): efficacy as a single agent and in combination. Semin Oncol 1995; 22: 3-16.
-
(1995)
Semin Oncol
, vol.22
, pp. 3-16
-
-
Bissery, M.C.1
Vrignaud, P.2
Lavelle, F.3
-
20
-
-
0029738931
-
Schedule-dependent interaction between paclitaxel and 5-fluorouracil in human carcinoma cell lines in vitro
-
Kano Y, Akutsu M, Tsunoda S, et al. Schedule-dependent interaction between paclitaxel and 5-fluorouracil in human carcinoma cell lines in vitro. Br J Cancer 1996; 74: 704-10.
-
(1996)
Br J Cancer
, vol.74
, pp. 704-710
-
-
Kano, Y.1
Akutsu, M.2
Tsunoda, S.3
-
21
-
-
0029832490
-
Taxoids in combination chemotherapy for metastatic breast cancer
-
Dieras V, Fumoleau P, Bourgeois H, Misset JL, Azly N, Pouillart P. Taxoids in combination chemotherapy for metastatic breast cancer. Anti-Cancer Drugs 1996; 7: 47-52.
-
(1996)
Anti-Cancer Drugs
, vol.7
, pp. 47-52
-
-
Dieras, V.1
Fumoleau, P.2
Bourgeois, H.3
Misset, J.L.4
Azly, N.5
Pouillart, P.6
-
22
-
-
0026808448
-
Combined antimicrotubule activity of estramustine and taxol in human prostatic carcinoma cell lines
-
Speicher LA, Barone L, Tew KD. Combined antimicrotubule activity of estramustine and taxol in human prostatic carcinoma cell lines. Cancer Res 1992; 52: 4433-40.
-
(1992)
Cancer Res
, vol.52
, pp. 4433-4440
-
-
Speicher, L.A.1
Barone, L.2
Tew, K.D.3
-
23
-
-
0028153260
-
Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: A rational approach to clinical protocol design
-
Chou TC, Motzer RJ, Tong Y, Bost GJ. Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: a rational approach to clinical protocol design. J Natl Cancer Inst 1994; 86: 1517-24.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1517-1524
-
-
Chou, T.C.1
Motzer, R.J.2
Tong, Y.3
Bost, G.J.4
-
24
-
-
0030005778
-
Pilot study of vinorelbine (navelbine) and paclitaxel in patients with refractory non-small cell lung cancer
-
Chang AY, DeVore R, Johnson D. Pilot study of vinorelbine (navelbine) and paclitaxel in patients with refractory non-small cell lung cancer. Semin Oncol 1996; 23: 19-21.
-
(1996)
Semin Oncol
, vol.23
, pp. 19-21
-
-
Chang, A.Y.1
DeVore, R.2
Johnson, D.3
-
25
-
-
0031106360
-
In vitro synergy of paclitaxel (Taxol) and vinorelbine (Navelbine) against human melanoma cell lines
-
Photiou A, Shah P, Leong LK, Moss J, Retsas S. In vitro synergy of paclitaxel (Taxol) and vinorelbine (Navelbine) against human melanoma cell lines, Eur J Cancer 1997; 33: 463-70.
-
(1997)
Eur J Cancer
, vol.33
, pp. 463-470
-
-
Photiou, A.1
Shah, P.2
Leong, L.K.3
Moss, J.4
Retsas, S.5
-
26
-
-
0029021646
-
Vinorelbine tartrate and paclitaxel combinations: Enhanced activity against in vivo P388 murine leukemia cells
-
Knick V, Eberwein D, Miller C. Vinorelbine tartrate and paclitaxel combinations: enhanced activity against in vivo P388 murine leukemia cells. J Natl Cancer Inst 1995; 87: 1072-7.
-
(1995)
J Natl Cancer Inst
, vol.87
, pp. 1072-1077
-
-
Knick, V.1
Eberwein, D.2
Miller, C.3
-
27
-
-
0029909870
-
Paclitaxel and vinorelbine in anthracycline-pretreated breast cancer: A phase- II study
-
Michelotti A, Gennari A, Salvadori B, et al. Paclitaxel and vinorelbine in anthracycline-pretreated breast cancer: a phase- II study. Ann Oncol 1996; 7: 857-60.
-
(1996)
Ann Oncol
, vol.7
, pp. 857-860
-
-
Michelotti, A.1
Gennari, A.2
Salvadori, B.3
-
28
-
-
0000747022
-
Final results of a phase I dose finding and pharmacokinetic (PK) study of docetaxel in combination with vinorelbine in metastatic breast cancer
-
Fumoleau P, Delecroix V, Perrocheau G, et al. Final results of a phase I dose finding and pharmacokinetic (PK) study of docetaxel in combination with vinorelbine in metastatic breast cancer. Ann Oncol 1996; 7: 126.
-
(1996)
Ann Oncol
, vol.7
, pp. 126
-
-
Fumoleau, P.1
Delecroix, V.2
Perrocheau, G.3
-
29
-
-
0029944673
-
Taxol and vinorelbine: A new active combination for disseminated malignant melanoma
-
Retsas S, Mohith A, Mackenzie H. Taxol and vinorelbine: a new active combination for disseminated malignant melanoma Anti-Cancer Drugs 1996; 7: 161-5.
-
(1996)
Anti-Cancer Drugs
, vol.7
, pp. 161-165
-
-
Retsas, S.1
Mohith, A.2
Mackenzie, H.3
-
31
-
-
0024361643
-
Suramin inhibits cell growth and glycolytic activity and triggers differentiation on human colic adenocarcinoma cell clone HT29-D4
-
Fantini J, Rognoni JB, Roccabianca M, Pommier G, Marvaldi J. Suramin inhibits cell growth and glycolytic activity and triggers differentiation on human colic adenocarcinoma cell clone HT29-D4. J Biol Chem 1989; 264: 10282-6.
-
(1989)
J Biol Chem
, vol.264
, pp. 10282-10286
-
-
Fantini, J.1
Rognoni, J.B.2
Roccabianca, M.3
Pommier, G.4
Marvaldi, J.5
-
32
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55-63.
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
33
-
-
0029103212
-
Simultaneous combination of microtubule depolymerizing and stabilizing agents acts at low doses
-
Garcia P, Braguer D, Carles G, Briand C. Simultaneous combination of microtubule depolymerizing and stabilizing agents acts at low doses. Anti-Cancer Drugs 1995; 6: 533-44.
-
(1995)
Anti-Cancer Drugs
, vol.6
, pp. 533-544
-
-
Garcia, P.1
Braguer, D.2
Carles, G.3
Briand, C.4
-
34
-
-
0023139279
-
Comparison of 1,2-dihydropyrido[3,4-6] pyrazynes (1-deaza-7,8-dihydropteridines) with several other inhibitors of mitosis
-
Boxdon BJ, Waud WR, Wheeler GP, Hain R, Dansby C, Temple C. Comparison of 1,2-dihydropyrido[3,4-6] pyrazynes (1-deaza-7,8-dihydropteridines) with several other inhibitors of mitosis. Cancer Res 1987; 47: 1621-6.
-
(1987)
Cancer Res
, vol.47
, pp. 1621-1626
-
-
Boxdon, B.J.1
Waud, W.R.2
Wheeler, G.P.3
Hain, R.4
Dansby, C.5
Temple, C.6
-
35
-
-
0028044792
-
Inhibition of microtubules and cell cycle arrest by a new 1-deaza-7,8-dihydropteridine antitumor drug, and by its chiral isomer, NSC 613863
-
De Ines C, Leynadier D, Barasoain I, et al. Inhibition of microtubules and cell cycle arrest by a new 1-deaza-7,8-dihydropteridine antitumor drug, and by its chiral isomer, NSC 613863. Cancer Res 1994; 54: 75-84.
-
(1994)
Cancer Res
, vol.54
, pp. 75-84
-
-
De Ines, C.1
Leynadier, D.2
Barasoain, I.3
-
36
-
-
0028143480
-
Characterization of a navelbine-resistant bladder carcinoma cell line cross-resistant to taxoids
-
Debal V, Allam N, Morjani H, et al. Characterization of a navelbine-resistant bladder carcinoma cell line cross-resistant to taxoids. Br J Cancer 1994; 70: 1118-25.
-
(1994)
Br J Cancer
, vol.70
, pp. 1118-1125
-
-
Debal, V.1
Allam, N.2
Morjani, H.3
-
37
-
-
0028070358
-
1 phase by interference spindle formation without affecting other microtubule functions during anaphase and telephase
-
1 phase by interference spindle formation without affecting other microtubule functions during anaphase and telephase. Cancer Res 1994; 54: 4335-61.
-
(1994)
Cancer Res
, vol.54
, pp. 4335-4361
-
-
Long, B.H.1
Fairchild, C.R.2
-
38
-
-
0030020158
-
Mitotic block induced in Hela cells by low concentrations of Paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death
-
Jordan MA, Wenkell K, Gardiner S, Derry W, Copp M, Wilson L. Mitotic block induced in Hela cells by low concentrations of Paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death. Cancer Res 1996; 56: 816-25.
-
(1996)
Cancer Res
, vol.56
, pp. 816-825
-
-
Jordan, M.A.1
Wenkell, K.2
Gardiner, S.3
Derry, W.4
Copp, M.5
Wilson, L.6
-
39
-
-
0025688199
-
Microtubules are stabilized in confluent epithelial cells but not in fibroblasts
-
Pepperkok R, Bre MH, Davoust J, Kreis TE. Microtubules are stabilized in confluent epithelial cells but not in fibroblasts. J Cell Biol 1990; 111: 3003-12.
-
(1990)
J Cell Biol
, vol.111
, pp. 3003-3012
-
-
Pepperkok, R.1
Bre, M.H.2
Davoust, J.3
Kreis, T.E.4
-
40
-
-
0023403268
-
Microtubules containing detyrosinated tubulin are less dynamic
-
Kreis TE. Microtubules containing detyrosinated tubulin are less dynamic. EMBO J 1987; 6: 2597-606.
-
(1987)
EMBO J
, vol.6
, pp. 2597-2606
-
-
Kreis, T.E.1
-
41
-
-
0027365430
-
Identification and molecular characterization of E-MAP-115, a novel microtubule-associated protein predominantly expressed in epithelial cells
-
Masson D, Kreis T. Identification and molecular characterization of E-MAP-115, a novel microtubule-associated protein predominantly expressed in epithelial cells J Cell Biol 1993; 133: 357-71.
-
(1993)
J Cell Biol
, vol.133
, pp. 357-371
-
-
Masson, D.1
Kreis, T.2
-
42
-
-
0028140020
-
Cellular microtubules heterogeneous in their content of microtubule-associated protein 4 (MAP4)
-
Chapin SJ, Bulinski JC. Cellular microtubules heterogeneous in their content of microtubule-associated protein 4 (MAP4). Cell Motil Cytosk 1994; 27: 133-49.
-
(1994)
Cell Motil Cytosk
, vol.27
, pp. 133-149
-
-
Chapin, S.J.1
Bulinski, J.C.2
-
43
-
-
0029781269
-
Differential expression of tubulin isotypes during the cell cycle
-
Dumontet C, Duran GE, Steger KA, et al. Differential expression of tubulin isotypes during the cell cycle. Cell Motil Cytosk 1996; 35: 49-58.
-
(1996)
Cell Motil Cytosk
, vol.35
, pp. 49-58
-
-
Dumontet, C.1
Duran, G.E.2
Steger, K.A.3
-
44
-
-
0030931827
-
Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific-tubulin isotypes
-
. Kavallaris M, Kuo D, Burkhart CA, et al. Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific-tubulin isotypes. J Clin Invest 1997; 100: 1282-93.
-
(1997)
J Clin Invest
, vol.100
, pp. 1282-1293
-
-
Kavallaris, M.1
Kuo, D.2
Burkhart, C.A.3
-
45
-
-
0031036307
-
Raf-1/bcl-2 phosphorylation: A step from microtubule damage to cell death
-
Blagosklonny MV, Giannakakou P, El-Deiry WS, et al. Raf-1/bcl-2 phosphorylation: a step from microtubule damage to cell death. Cancer Res 1997; 57: 130-5.
-
(1997)
Cancer Res
, vol.57
, pp. 130-135
-
-
Blagosklonny, M.V.1
Giannakakou, P.2
El-Deiry, W.S.3
-
48
-
-
0027988155
-
Immunohistochemical analysis of in vivo patterns of Bcl-x expression
-
Krajewski S, Krajewska M, Shabaik A, et al. Immunohistochemical analysis of in vivo patterns of Bcl-x expression. Cancer Res 1994; 54: 5501-7.
-
(1994)
Cancer Res
, vol.54
, pp. 5501-5507
-
-
Krajewski, S.1
Krajewska, M.2
Shabaik, A.3
-
49
-
-
0029939651
-
Increased intestinal Bak expression results in apoptosis
-
Moss SF, Agarwal B, Arber N, et al. Increased intestinal Bak expression results in apoptosis. Biochem Biophys Res Commun 1996; 223: 199-203.
-
(1996)
Biochem Biophys Res Commun
, vol.223
, pp. 199-203
-
-
Moss, S.F.1
Agarwal, B.2
Arber, N.3
-
50
-
-
0031036695
-
p53 status does not affect sensitivity of human ovarian cancer cell lines to paclitaxel
-
Debernadis D, Siré EG, De Feudis P, et al. p53 status does not affect sensitivity of human ovarian cancer cell lines to paclitaxel. Cancer Res 1997; 57: 870-4.
-
(1997)
Cancer Res
, vol.57
, pp. 870-874
-
-
Debernadis, D.1
Siré, E.G.2
De Feudis, P.3
-
51
-
-
0028881885
-
Induction of the differentiated phenotype in human colon cancer cells is associated with the attenuation of subcellular tyrosine phosphorylation
-
Schwartz B, Lamprecht SA, Polak-Charcon S, Niv Y, Kim YS. Induction of the differentiated phenotype in human colon cancer cells is associated with the attenuation of subcellular tyrosine phosphorylation. Oncol Res 1995; 7: 277-87.
-
(1995)
Oncol Res
, vol.7
, pp. 277-287
-
-
Schwartz, B.1
Lamprecht, S.A.2
Polak-Charcon, S.3
Niv, Y.4
Kim, Y.S.5
-
52
-
-
0030929913
-
Select alterations in protein kinases and phosphatases during apoptosis of differentiated PC12 cells
-
Davis PK, Dudek SM, Johnson GV. Select alterations in protein kinases and phosphatases during apoptosis of differentiated PC12 cells. J Neurochem 1997; 68: 2338-47.
-
(1997)
J Neurochem
, vol.68
, pp. 2338-2347
-
-
Davis, P.K.1
Dudek, S.M.2
Johnson, G.V.3
-
53
-
-
0011886457
-
Clinical activity in other tumors
-
McGuire WP, Rowinsky EK, eds. New York: Marcel Dekker
-
Muggia FM. Clinical activity in other tumors. In: McGuire WP, Rowinsky EK, eds. Paclitaxel in cancer treatment. New York: Marcel Dekker 1995: 329-37.
-
(1995)
Paclitaxel in Cancer Treatment
, pp. 329-337
-
-
Muggia, F.M.1
|