Production of dihydroabikoviromycin by Streptomyces anulatus: Production parameters and chemical characterization of genotoxicity

Journal of Applied Microbiology

Volumn 85, Issue 1, 1998, Pages 61-68

  Holmalahti, J ^a,d   Raatikainen, O ^a   Von Wright, A ^a   Laatsch, H ^b   Spohr, A ^c   Lyngberg, O K ^c   Nielsen, J ^c  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^d NATIONAL AGENCY FOR MEDICINES   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CHLORINE COMPOUNDS;

AMMONIA CONCENTRATIONS; BIOASSAY DIRECTED FRACTIONATION; CHEMICAL CHARACTERIZATION; CHLOROFORM EXTRACTS; GENOTOXIC ACTIVITY; GENOTOXICITIES; GENOTOXINS; MORPHOLOGICAL PARAMETERS; PARAMETER CHARACTERIZATION; PRODUCTION PARAMETERS;

ESCHERICHIA COLI;

BACTERIAL TOXIN; DIHYDROABIKOVIROMYCIN; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; DNA CLEAVAGE; DRUG DETERMINATION; DRUG EFFECT; DRUG SYNTHESIS; GENOTOXICITY; NONHUMAN; STREPTOMYCES;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; STREPTOMYCES ANULATUS;

EID: 0031950447     PISSN: 13645072     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2672.1998.00472.x     Document Type: Article

References (26)

1. Benthin, S., Nielsen, J. and Villadsen, J. (1991) Characterization and application of precise and robust flow-injection analysers for on-line measurement during fermentations. Analytica Chimica Acta 247, 45-50.
2. Bergter, F.Z. (1978) Kinetic model of mycelial growth. Zeitschrift fur Allgemeine Mikrobiologie 18, 143-145.
3. Cross, T. (1982) Actinomycetes : a continuing source of new metabolites. Developments in Industrial Microbiology 23, 1-8.
4. Daza, A., Martin, J.F., Dominguez, A. and Gil, J.A. (1989) Sporulation of several species of Streptomyces in submerged cultures after nutritional downshift. Journal of General Microbiology 135, 2483-2491.
5. Glazebrook, M.A., Doull, J.L., Stuttard, C. and Vining, L.C. (1990) Sporulation of Streptomyces venezuelae in submerged cultures. Journal of General Microbiology 136, 581-588.
6. + reversion in Escherichia coli. Mutation Research 38, 3-32.
7. Holmalahti, J., Raatikainen, O. and von Wright, A. (1994) Variations in spectra of biological activities of actinomycetes isolated from different soils. Letters in Applied Microbiology 18, 144-146.
8. Hunter-Cevera, J.C., Fonda, M.E. and Belt, A. (1986) Isolation of cultures. In Manual of Industrial Microbiology and Biotechnology ed. Demain, A.L. and Solomon, N.A. p. 3. Washington DC: American Society for Microbiology.
9. Jensen, P.R., Dwight, R. and Fenical, W. (1991) Distribution of actinomycetes in near-shore tropical marine sediments. Applied and Environmental Microbiology 57, 1102-1108.
10. Kendrick, K. and Ensign, J.C. (1990) Sporulation of Streptomyces griseus in submerged culture. Journal of Bacteriology 155, 357-366.
11. Laatsch, H. (1994) AntiBase, A Microbial Metabolites Database. Weinheim, Germany : Chemical Concepts.
12. Miles, E.A. and Trinci, A.P.J. (1983) Effect of pH and temperature on morphology of batch and chemostat cultures of Penicillium chrysogenum. Transactions of the British Mycological Society 81, 517-520.
13. Nielsen, J. (1993) A simple morphologically structured model describing the growth of filamentous microorganisms. Biotechnology and Bioengineering 41, 715-727.
14. Nielsen, J. and Krabben, P. (1995) Hyphal growth and fragmentation of P. chrysogenum in submerged cultures. Biotechnology and Bioengineering 46, 588-598.
15. Nielsen, J. and Villadsen, J. (1994) Bioreaction Engineering Principles. New York : Plenum Press.
16. Ogawa, Y., Tsuruoka, T., Shomura, T., Watanabe, H., Inouye, S. and Nida, T. (1973) On the synergism of SF-973 B and C. Journal of Antibiotics 26, 186-188.
17. Pisano, M.A., Sommer, M.J. and Brett, B.P. (1987) Hudson river sediments as a source of actinomycetes exhibiting antifungal activity. Applied Microbiology and Biotechnology 27, 214-217.
18. Räty, K., Raatikainen, O., Holmalahti, J. et al. (1995) Biological activities of actinomycetes and fungi isolated from the indoor air of problem houses. International Biodeterioration and Biodegradation 34, 143-154.
19. Sambrook, J., Fritsch, F.F. and Maniatis, T. (1989) Molecular Cloning. A Laboratory Manual, 2nd edn. Cold Spring Harbor : Cold Spring Harbor Laboratory Press.
20. Spohr, A., Carslen, M., Nielsen, J. and Villadsen, J. (1997) Morphological characterization of recombinant strains of Aspergillus oryzae producing α-amylase during batch cultivations. Biotechnology Letters 19, 257-261.
21. Takahashi, S., Serita, K., Enokita, R., Okaza, T. and Haneishi, T. (1986) A new antibiotic, N-Hydroxydihydroabikoviromycin. Sankyo Kenkyusho Nempo 38, 105-108.
22. Trinci, A.P.J. (1971) Influence of the width of the peripheral growth zone on the radical growth rate of fungal colonies on solid media. Journal of General Microbiology 67, 325-344.
23. Tsuruoka, T., Shomura, T., Ogawa, Y. et al. (1973) Some properties of SF-973 B substance, the enzyme catalyzing the conversion of dihydroabikoviromycin to abikoviromycin. Journal of Antibiotics 26, 168-174.
24. Tweats, D.J., Green, M.H.L. and Muriel, W.J. (1981) A differential killing assay for mutagens and carcinogens based on an improved repair-deficient strain of Escherichia coli. Carcinogenesis 2, 189-194.
25. Williams, S.T., Goodfellow, M., Wellington, E.M.H., Sneath, P.H.A. and Sackin, M.J. (1983a) Numerical classification of Streptomyces and related genera. Journal of General Microbiology 129, 1743-1813.
26. Williams, S.T., Goodfellow, M., Wellington, E.M.H. et al. (1983b) A probability matrix for the identification of some streptomycetes. Journal of General Microbiology 129, 1815-1830.