Spindle cell sarcoma of the kidney with ganglionic elements (malignant ectomesenchymoma) associated with chromosomal abnormalities and a review of the literature

Journal of Pediatric Hematology/Oncology

Volumn 20, Issue 2, 1998, Pages 160-164

  Goldsby, Robert E ^a   Bruggers, Carol S ^a   Brothman, Arthur R ^a   Sorensen, Poul H B ^c   Beckwith, J Bruce ^b   Pysher, Theodore J ^a  

^a PRIMARY CHILDREN'S MEDICAL CENTER   (United States)

^b LOMA LINDA UNIVERSITY   (United States)

^c School of Medicine ^*

Author keywords

Chemotherapy; Cytogenetics; Diagnosis; Immunohistochemical stains; Malignant ectomesenchymomas; Outcome; Radiation therapy; Renal neoplasms; Spindle cell sarcoma; T(12; 15)

Indexed keywords

CYCLOPHOSPHAMIDE; DACTINOMYCIN; DOXORUBICIN; MESNA; VINCRISTINE;

ARTICLE; CANCER ADJUVANT THERAPY; CANCER RADIOTHERAPY; CASE REPORT; CHROMOSOME 15; CHROMOSOME ABERRATION; CHROMOSOME TRANSLOCATION 12; HISTOPATHOLOGY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY SARCOMA; MALE; MESENCHYMOMA; NEPHRECTOMY; PRESCHOOL CHILD; PRIORITY JOURNAL; SPINDLE CELL SARCOMA; TREATMENT OUTCOME;

CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; COMBINED MODALITY THERAPY; GANGLIA; HUMANS; INFANT; KIDNEY NEOPLASMS; MALE; MESENCHYMOMA; SARCOMA; TREATMENT OUTCOME;

EID: 0031949716     PISSN: 10774114     EISSN: None     Source Type: Journal    
DOI: 10.1097/00043426-199803000-00015     Document Type: Article

References (21)

1. Pizzo PA, Poplack DG. Principles and Practice of Pediatric Oncology. Philadelphia: Lippincott-Raven Publishers, 1997:174-5.
2. Sorensen PHB, Shimada H, Liu JF, et al. Biphenotypic sarcomas with myogenic and neural differentiation express the Ewing's sarcoma EWS/FLI1 fusion gene. Cancer Res 1995;55:1385-92.
3. Sorensen P, Liu X, Thomas G, et al. (1993) Reverse transcriptase PCR amplification of EWS/FLI1 fusion transcripts as a diagnostic test for peripheral primitive neuroectodermal tumors of childhood. Diagn Mol Pathol 1993;2:147-57.
4. Karcioglu Z, Someren A, Mathes SJ. Ectomesenchymoma: a malignant tumour of migratory neural crest (ectomesenchyme) remnants showing ganglionic, Schwannian, melanocytic, and rhabdomyoblastic differentiation. Cancer 1977;39:2486-96.
5. Kasantikul V, Shuangshoi S, Cutchavaree A, et al. Parapharyngeal malignant ectomesenchymoma: Combined malignant fibrous histiocytoma and primitive neuroectodermal tumor with neuroglial differentiation. J Laryngol Otol 1987;101:508-15.
6. Kawamoto EH, Weidner N, Agostini RM, et al. Malignant ectomesenchymoma of soft tissue. Report of two cases and review of the literature. Cancer 1987;59:1791-802.
7. Cozzutto C, Comelli A, Bandelloni R. Ectomesenchymoma: report of two cases. Virch Arch (Patol Anat) 1982;398:185-95.
8. Holimon JL, Rosenblum WI. Gangliorhabdomyosarcoma: a tumor of ectomesenchyme. J Neurosurg 1971;34:417-22.
9. Kodet R, Kasthuri N, Marsden HB, et al. Gangliorhabdomyosarcoma: a histopathological and immunohistochemical study of three cases. Histopathology 1986;10:181-93.
10. Naka A, Matsumoto S, Shirai T, et al. Ganglioneuroblastoma associated with malignant mesenchymoma. Cancer 1975;36:1050-6.
11. Schmidt D, Mackay B, Osborne BM, et al. Recurring congenital lesion of the cheek. Ultrastruct Pathol 1982;3:85-90.
12. Matsko TH, Schmidt RA, Milam AH, et al. Primary malignant ectomesenchymoma of the orbit. Br J Ophthalmol 1992;76:438-41.
13. Kuo T. Observation of nervous tissue in a Wilms' tumor: its histogenetic significance. Cancer 1977;39:1105-8.
14. Llombart-Bosch A, Peydro-Olaya A, Cerda-Nicolas M. Presence of ganglion cells in Wilms' tumours: a review of the possible neuroepithelial origin of nephroblastoma. Histopathology 1980;4:321-30.
15. Grimes MM, Wolff M, Wolff JA, et al. Ganglion cells in metastatic Wilms' tumor. Am J Surg Pathol 1982;6:565-71.
16. Green DM, D'Angio GJ, Beckwith JB, et al. Wilms tumor. CA Cancer J Clin 1996;46:46-63.
17. Beckwith JB. Mesenchymal renal neoplasms of infancy revisited. J Pediatr Surg 1974;9:803-5.
18. Joshi VV, Kasznica J, Walters TR. Atypical mesoblastic nephroma: pathologic characterization of a potentially aggressive varient of conventional congenital mesoblastic nephroma. Arch Pathol Lab Med 1986;110:100-6.
19. Lowery M, Issa B, Pysher T, et al. Cytogenetic findings in a case of congenital mesoblastic neproma. Cancer Genet Cytogenet 1995;84:113-5.
20. Kaneko Y, Homma C, Maskeki N, et al. Correlation of chromosome abnormalities with histological and clinical features in Wilm's and other childhood renal tumors. Cancer Res 1991;51:5937-42.
21. Schofield DE, Yunis EJ, Fletcher JA. Chromosome aberrations in mesoblastic nephroma. Am J Pathol 1993;143:14-724.