Effects of dissolved oxygen levels and the role of extra- and intracellular amino acid concentrations upon the metabolism of mammalian cell lines during batch and continuous cultures

Cytotechnology

Volumn 26, Issue 3, 1998, Pages 185-197

  Heidemann, Rüdiger ^a,b   Lütkemeyer, Dirk ^a   Büntemeyer, Heino ^a   Lehmann, Jürgen ^a  

^a BIELEFELD UNIVERSITY   (Germany)

^b BAYER CORPORATION   (United States)

Author keywords

CHO; Dissolved oxygen (DO); Essential amino acids; Hybridoma; Intracellular amino acids; Monod constants (K(S) values); Productivity; Specific uptake rates

Indexed keywords

CELL LINE; CELL METABOLISM; COMPUTER SIMULATION; MONOD EQUATION;

EID: 0031949631     PISSN: 09209069     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007917409455     Document Type: Article

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