Influence of adjunctive ticlopidine on the treatment of experimental Staphylococcus aureus endocarditis

International Journal of Antimicrobial Agents

Volumn 9, Issue 4, 1998, Pages 227-229

  Nicolau, David P ^a,b   Tessier, Pamela R ^a   Nightingale, Charles H ^a,b   Quintiliani, Richard ^a,c  

^a HARTFORD HOSPITAL   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

^c UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

Author keywords

Antiplatelet therapy; Staphylococcus aureus endocarditis; Ticlopidine

Indexed keywords

ANTIINFECTIVE AGENT; ANTITHROMBOCYTIC AGENT; TICLOPIDINE; VANCOMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL THERAPY; AORTA VALVE; ARTICLE; BACTERIAL ENDOCARDITIS; BACTERIUM ISOLATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; EXPERIMENTAL INFECTION; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; RABBIT; STAPHYLOCOCCUS AUREUS; VEGETATION;

ANIMALS; ANTI-BACTERIAL AGENTS; ENDOCARDITIS, BACTERIAL; FEMALE; PLATELET AGGREGATION INHIBITORS; RABBITS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TICLOPIDINE; TREATMENT OUTCOME;

EID: 0031949396     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-8579(97)00056-3     Document Type: Article

References (8)

1. Nicolau DP, Freeman CD, Nightingale CH et al. Reduction of bacterial titers by low-dose aspirin in experimental aortic valve endocarditis. Infect Immun. 61:1993;1593-1595.
2. Nicolau DP, Marangos MN, Nightingale CH, Quintiliani R Influence of aspirin on the development and treatment of experimental S. aureus endocarditis. Antimicrob Agents Chemother. 39:1995;1748-1751.
3. Nicolau DP, Tessier PR, Nightingale CH, Quintiliani R Influence of ticlopidine on the development of experimental Staphylococcus aureus endocarditis. Int J Antimicrob Agents. 7:1996;271-274.
4. National Institutes of Health (NIH). Guide for the care and use of laboratory animals. NIH Pub. No. 85-23. Washington, D.C.: US Department of Health and Human Services, 1985.
5. Durack DT, Beeson PB, Petersdorf RG Experimental bacterial endocarditis. III. Production and progress of the disease in rabbits. Br J Exp Pathol. 54:1973;142-151.
6. Garrison PK, Freedman LR Experimental endocarditis. I. Staphylococcal endocarditis in rabbits resulting from placement of a polyethylene catheter in the right side of the heart. Yale J Biol Med. 42:1970;394-410.
7. Taha TH, Durrant SS, Mazeika PK, Nihoyannopoulos P, Oakley CM Aspirin to prevent growth of vegetations and cerebral emboli in infective endocarditis. J Intern Med. 231:1992;534-546.
8. Schomig A, Neumann FJ, Ksatrati A et al. A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stems. N Engl J Med. 334:1996;1084-1089.