Intracellular complexes of viral spike and cellular receptor accumulate during cytopathic murine coronavirus infections

Journal of Virology

Volumn 72, Issue 4, 1998, Pages 3278-3288

  Rao, Pasupuleti V ^a   Gallagher, Thomas M ^a  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS RECEPTOR;

ARTICLE; CELL DEATH; CORONAVIRUS; CYTOPATHOGENIC EFFECT; CYTOPATHOLOGY; HELA CELL; HUMAN; HUMAN CELL; MURINE HEPATITIS CORONAVIRUS; PRIORITY JOURNAL; PROMOTER REGION; SYNCYTIUM; VIRUS CELL INTERACTION; VIRUS INFECTION;

EID: 0031949315     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.4.3278-3288.1998     Document Type: Article

References (59)

1. Ahmed, R., L. A. Morrison, and D. M. Knipe. 1996. Persistence of viruses, p. 219-249. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Fields virology, vol. 1, 3rd ed. Lippincott-Raven, New York, N.Y.
2. Alexander, W. A., B. Moss, and T. R. Fuerst. 1992. Regulated expression of foreign genes in vaccinia virus under the control of bacteriophage T7 RNA polymerase and the Escherichia coli lac represser. J. Virol. 66:2934-2942.
3. Aroeti, B., and Y. I. Henis. 1988. Effects of fusion temperature on the lateral mobility of sendai virus glycoproteins in erythrocyte membranes and on cell fusion indicate that glycoprotein mobilization is required for cell fusion. Biochemistry 27:5654-5661.
4. Asjö, B., I. Ivhed, M. Gidlund, S. Fuerstenberg, E. M. Fenyö, K. Nilsson, and H. Wigzell. 1987. Susceptibility to infection by the human immunodeficiency virus (HIV) correlates with T4 expression in a parental monocytoid cell lines and its subclones. Virology 157:359-365.
5. Baron, U., M. Gossen, and H. Bujard. 1997. Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential. Nucleic Acids Res. 25:2723-2729.
6. Baybutt, H. N., H. Wege, M. J. Carter, and V. Ter Meulen. 1984. Adaptation of coronavirus JHM to persistent infection of murine Sac (-) cells. J. Gen. Virol. 65:915-924.
7. Buchmeier, M. J., R. M. Welsh, F. J. Dutko, and M. B. A. Oldstone. 1980. The virology and immunology of lymphocytic choriomeningitis virus infection. Adv. Immunol. 30:275-331.
8. Cao, J., I.-W. Park, A. Cooper, and J. Sodroski. 1996. Molecular determinants of acute single-cell lysis by human immunodeficiency virus type 1. J. Virol. 70:1340-1354.
9. Cervin, M., and R. Anderson. 1991. Modulation of coronavirus-mediated cell fusion by homeostatic control of cholesterol and fatty acid metabolism. J. Med. Virol. 35:142-149.
10. Chen, W., V. J. Madden, C. R. Bagnell, Jr., and R. S. Baric. 1997. Host-derived intracellular immunization against mouse hepatitis virus infection. Virology 228:318-332.
11. Chen, W., and R. S. Baric. 1996. Molecular anatomy of mouse hepatitis virus persistence: coevolution of increased host cell resistance and virus virulence. J. Virol. 70:3947-3960.
12. Collins, A. R., R. L. Knobler, H. Powell, and M. J. Buchmeier. 1982. Monoclonal antibodies to murine hepatitis virus-4 (strain JHM) define the viral glycoprotein responsible for attachment and cell-cell fusion. Virology 119: 358-371.
13. Dales, S., and R. Anderson. 1995. Pathogenesis and diseases of the central nervous system caused by murine coronaviruses, p. 257-292. In S. G. Siddell (ed.), The Coronaviridae. Plenum Press, New York, N.Y.
14. Dalziel, R. G., P. W. Lampert, P. J. Talbot, and M. J. Buchmeier. 1986. Site-specific alteration of murine hepatitis virus type 4 peplomer glycoprotein E2 results in reduced neurovirulence. J. Virol. 59:463-471.
15. Danieli, T., S. L. Pelletier, Y. I. Henis, and J. M. White. 1996. Membrane fusion mediated by influenza virus hemagglutinin requires the concerted action of at least three hemagglutinin trimers. J. Cell Biol. 133:559-569.
16. Davies, H. A., and M. R. Macnaughton. 1979. Comparison of the morphology of three coronaviruses. Arch. Virol. 59:25-33.
17. Daya, M., M. Cervin, and R. Anderson. 1988. Cholesterol enhances mouse hepatitis virus-mediated cell fusion. Virology 163:276-283.
18. Dennody, T. S., M. L. Nibert, J. D. Wetzel, X. Tong, and B. N. Fields. 1993. Cells and viruses with mutations affecting viral entry are selected during persistent infections of L cells with mammalian reoviruses. J. Virol. 67:2055-2063.
19. Dveksler, G. S., A. A. Basile, C. B. Cardellichio, and K. V. Holmes. 1995. Mouse hepatitis virus receptor activities of an MHVR/mph chimera and MHVR mutants lacking N-linked glycosvlation of the N-terminal domain. J. Virol. 69:543-546.
20. Dveksler, G. S., M. N. Pensiero, C. W. Dieffenbach, C. B. Cardellichio, A. A. Basile, P. E. Elia, and K. V. Holmes. 1993. Mouse hepatitis virus strain A59 and blocking antireceptor monoclonal antibody bind to the N-terminal domain of cellular receptor. Proc. Natl. Acad. Sci. USA 90:1716-1720.
21. Dveksler, G. S., M. N. Pensiero, C. B. Cardellichio, R. K. Williams, G.-S. Jiang, K. V. Holmes, and C. W. Dieffenbach. 1991. Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV. J. Virol. 65:6881-6891.
22. Fazakerley, J. K., S. E. Parker, F. Bloom, and M. J. Buchmeier. 1992. The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system. Virology 187:178-188.
23. Frana, M. F., J. N. Behnke, L. S. Sturman, and K. V. Holmes. 1985. Proteolytic cleavage of the E2 glycoprotein of murine coronavirus:host-dependent differences in proteolytic cleavage and cell fusion. J. Virol. 56:912-920.
24. Frey, S., M. Marsh, S. Günther, A. Pelchen-Matthews, P. Stephens, S. Ortlepp, and T. Stegmann. 1995. Temperature dependence of cell-cell fusion induced by the envelope glycoprotein of human immunodeficiency virus type 1. J. Virol. 69:1462-1472.
25. Fuerst, T. R., P. L. Earl, and B. Moss. 1987. Use of a hybrid vaccinia virus-T7 RNA polymerase system for expression of target genes. Mol. Cell. Biol. 7:2538-2544.
26. Fuerst, T. R., E. G. Niles, F. W. Studier, and B. Moss. 1986. Eukaryotic transient expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase. Proc. Natl. Acad. Sci. USA 83:8122-8126.
27. Gagneten, S., O. Gout, M. Dubois-Dalcq, P. Rottier, J. Rossen, and K. V. Holmes. 1995. Interaction of mouse hepatitis virus (MHV) spike glycoprotein with receptor glycoprotein MHVR is required for infection with an MHV strain that expresses the hemagglutinin-esterase glycoprotein. J. Virol. 69:889-895.
28. Gallagher, T. M. 1997. A role for naturally occurring variation of the murine coronavirus spike protein in stabilizing association with the cellular receptor. J. Virol. 71:3129-3137.
29. Gallagher, T. M. 1996. Murine coronavirus membrane fusion is blocked by modification of thiols buried within the spike protein. J. Virol. 70:4683-4690.
30. Gallagher, T. M. 1995. Overexpression of the MHV receptor: effect on progeny virus secretion. Adv. Exp. Med. Biol. 380:331-336.
31. Gallagher, T. M., M. J. Buchmeier, and S. Perlman. 1992. Cell receptor-independent infection by a neurotropic murine coronavirus. Virology 191: 517-522.
32. Gallagher, T. M., C. Escarmis, and M. J. Buchmeier. 1991. Alteration of the pH dependence of coronavirus-induced cell fusion: effect of mutations in the spike glycoprotein. J. Virol. 65:1916-1928.
33. Gombold, J. L., S. T. Hingley, and S. R. Weiss. 1993. Fusion-defective mutants of mouse hepatitis virus A59 contain a mutation in the spike protein cleavage signal. J. Virol. 67:4504-4512.
34. Gossen, M., S. Freundlieb, G. Bender, G. Müller, W. Hillen, and H. Bujard. 1995. Transcriptional activation by tetracyclines in mammalian cells. Science 268:1766-1769.
35. Gossen, M., and H. Bujard. 1992. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA 89:5547-5551.
36. Klumperman, J., J. K. Locker, A. Meijer, M. C. Horzinek, H. J. Geuze, and P. J. M. Rottier. 1994. Coronavirus M proteins accumulate in the golgi complex beyond the site of virion budding. J. Virol. 68:6523-6534.
37. Knobler, R. L., P. W. Lampert, and M. B. A. Oldstone. 1982. Virus persistence and recurring demyelination produced by a temperature-sensitive mutant of MHV-4. Nature 298:279-280.
38. Konopka, K., E. Pretzer, and N. Duzgunes. 1995. Differential effects of a hydrophobic tripeptide on human immunodeficiency virus type 1 (HIV-1)-induced syncytium formation and viral infectivity. Biochem. Biophys. Res. Commun. 208:75-81.
39. Koolen, M. J. M., S. Love, W. Wouda, J. Calafat, M. C. Horzinek, and B. A. M. Van Der Zeijst. 1987. Induction of demyelination by a temperature-sensitive mutant of the coronavirus MHV-A59 is associated with restriction of viral replication in the brain. J. Gen. Virol. 68:703-714.
40. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
41. Lai, M. M. C. 1990. Coronavirus: organization, replication and expression of genome. Annu. Rev. Microbiol. 44:303-333.
42. Lavi, E., A. Suzumura, M. Hiragama, M. K. Highkin, D. M. Dambach, D. H. Silberberg, and S. R. Weiss. 1987. Coronavirus mouse hepatitis virus (MHV)-A59 causes persistent, productive infection in primary glial cell cultures. Microb. Pathol. 3:79.
43. Majno, G., and I. Joris. 1995. Apoptosis, oncosis and necrosis, an overview of cell death. Am. J. Pathol. 146:3-15.
44. Nash, T. C., and M. J. Buchmeier. 1996. Spike glycoprotein-mediated fusion in biliary glycoprotein-independent cell-associated spread of mouse hepatitis virus infection. Virology 223:68-78.
45. Nussbaum, O., C. C. Broder, and E. A. Berger. 1994. Fusogenic mechanisms of enveloped-virus glycoproteins analyzed by a novel recombinant vaccinia virus-based assay quantitating cell fusion-dependent reporter gene activation. J. Virol. 68:5411-5422.
46. Rao, P. V., S. Kumari, and T. M. Gallagher. 1997. Identification of a contiguous 6-residue determinant in the MHV receptor that controls the level of virion binding to cells. Virology 229:336-348.
47. Roos, D. S., C. S. Duchala, C. B. Stephensen, K. V. Holmes, and P. W. Choppin. 1990. Control of virus-induced cell fusion by host cell lipid composition. Virology 175:345-357.
48. Sawicki, S. G., J.-H. Lu, and K. V. Holmes. 1995. Persistent infection of cultured cells with mouse hepatitis virus (MHV) results from the epigenetic expression of the MHV receptor. J. Virol. 69:5535-5543.
49. Stohlman, S. A., A. Y. Sakaguchi, and L. P. Weiner. 1979. Characterization of the cold-sensitive murine hepatitis virus mutants rescued from latently infected cells by cell fusion. Virology 98:448-455.
50. Siess, D. C., S. L. Kozak, and D. Kabat. 1996. Exceptional fusogenicity of Chinese hamster ovary cells with murine retroviruses suggests roles for cellular factor(s) and receptor clusters in the membrane fusion process. J. Virol. 70:3432-3439.
51. Sturman, L. S., and K. K. Takemoto. 1972. Enhanced growth of a murine coronavirus in transformed mouse cells. Infect. Immun. 6:501-507.
52. Suzuki, H., and F. Taguchi. 1996. Analysis of the receptor-binding site of murine coronavirus spike protein. J. Virol. 70:2632-2636.
53. Taguchi, F. 1993. Fusion formation by the uncleaved spike protein of murine coronavirus JHMV variant cl-2. J. Virol. 67:1195-1202.
54. Taguchi, F., and S. G. Siddell. 1985. Differences in sensitivity to interferon among mouse hepatitis viruses with high and low virulence for mice. Virology 147:41-48.
55. Vennema, H., L. Heijnen, A. Zijderveld, M. C. Horzinek, and W. J. M. Spaan. 1990. Intracellular transport of recombinant coronavirus spike proteins: implications for virus assembly. J. Virol. 64:339-346.
56. Wang, F.-L., J. O. Fleming, and M. M. C. Lai. 1992. Sequence analysis of the spike protein gene of murine coronavirus variants: study of genetic sites affecting neuropathogenicity. Virology 186:742-749.
57. White, J. M. 1992. Membrane fusion. Science 258:917-924.
58. Williams, R. K., G.-S. Jiang, S. W. Snyder, M. F. Frana, and K. V. Holmes. 1990. Purification of the 110-kilodalton glycoprotein receptor for mouse hepatitis virus (MHV)-A59 from mouse liver and identification of a non-functional, homologous protein in MHV-resistant SJL/J mice. J. Virol. 64: 3817-3823.
59. Yokomori, K., and M. M. C. Lai. 1992. Mouse hepatitis virus utilizes two carcinoembryonic antigens as alternative receptors. J. Virol. 66:6194-6199.