Putative preneoplastic changes identified by enzyme histochemical and immunohistochemical techniques

Journal of Histochemistry and Cytochemistry

Volumn 46, Issue 5, 1998, Pages 577-583

  Pretlow, Theresa P ^a   Pretlow, Thomas G ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Cancel; Colon; Enzyme histochemistry; Glycol methacrylate embedding; Immunohistochemistry; Paraffin embedding; Premalignant lesions; Prostate; Whole mount tissue

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; COLON CANCER; COLON CARCINOGENESIS; CONFERENCE PAPER; CONTROLLED STUDY; HISTOCHEMISTRY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CANCER; LIVER CARCINOGENESIS; NONHUMAN; PRECANCER; PRIORITY JOURNAL; TISSUE SECTION;

ANIMALIA; RODENTIA;

EID: 0031949290     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215549804600503     Document Type: Conference Paper

References (52)

1. Augenlicht L (1994) Adhesion molecules, cellular differentiation and colonic crypt architecture. Gastroenterology 107:1894-1898
2. Augenlicht LH, Richards C, Corner G, Pretlow TP (1996) Evidence for genomic instability in human colonic aberrant crypt foci. Oncogene 12:1767-1772
3. Bannasch P, Gössner W (1994) Pathology of Neoplasia and Preneoplasia in Rodents. EULEP Color Atlas of Pathology. Vol 1. New York, FK Schattauer
4. Bannasch P, Gössner W (1997) Pathology of Neoplasia and Preneoplasia in Rodents. EULEP Color Atlas of Pathology. Vol 2. New York, FK Schattauer.
5. Barrow BJ, O'Riordan MA, Stellato TA, Calkins BM, Pretlow TP (1990) Enzyme-altered foci in colons of carcinogen-treated rats. Cancer Res 50:1911-1916
6. Barrow BJ, Ortiz-Reyes R, O'Riordan MA, Stellato TA, Pretlow TP (1988) Putative preneoplastic foci in colons of dimethylhydrazine-treated rats. FASEB J 2:A1154
7. Beckstead JH, Halverson PS, Ries CA, Bainton DF (1981) Enzyme histochemistry and immunohistochemistry on biopsy specimens of pathologic human bone marrow. Blood 57:1088-1098
8. Bird RP (1987) Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett 37:147-151
9. Bird RP (1995) Role of aberrant crypt foci in understanding the pathogenesis of colon cancer. Cancer Lett 93:55-71
10. Caderni G, Giannini A, Lancioni L, Luceri C, Biggeri A, Dolara P (1995) Characterisation of aberrant crypt foci in carcinogen-treated rats: association with intestinal carcinogenesis. Br J Cancer 71:763-769
11. Gown AM, de Wever N, Battifora H (1993) Microwave-based antigenic unmasking. A revolutionary new technique for routine immunohistochemistry. Appl Immunohistochem 1:256-266
12. Heinen CD, Shivapurkar N, Tang Z, Groden J, Alabaster O (1996) Microsatellite instability in aberrant crypt foci from human colons. Cancer Res 56:5339-5341
13. Jen J, Powell SM, Papadopoulos N, Smith KJ, Hamilton SR, Vogelstein B, Kinzler KW (1994) Molecular determinants of dysplasia in colorectal lesions. Cancer Res 54:5523-5526
14. Konstantakos AK, Siu I-M, Pretlow TG, Stellato TA, Pretlow TP (1996) Human aberrant crypt foci with carcinoma in situ from a patient with sporadic colon cancer. Gastroenterology 111: 772-777
15. Magnuson BA, Carr I, Bird RP (1993) Ability of aberrant crypt foci characteristics to predict colonic tumor incidence in rats fed cholic acid. Cancer Res 53:4499-4504
16. McLellan EA, Bird RP (1988) Specificity study to evaluate induction of aberrant crypts in murine colons. Cancer Res 48:6183-6186
17. McLellan EA, Medline A, Bird RP (1991a) Sequential analyses of the growth and morphological characteristics of aberrant crypt foci: Putative preneoplastic lesions. Cancer Res 51:5270-5274
18. McLellan EA, Medline A, Bird RP (1991b) Dose response and proliferative characteristics of aberrant crypt foci: putative preneoplastic lesions in rat colon. Carcinogenesis 12:2093-2098
19. Monger LE Jr., Nagabhushan M, Pretlow TG, Pretlow TP (1994) A novel approach to the characterization of whole prostate pathology in glycol methacrylate. Am J Pathol 145:54-60
20. O'Riordan MA, Barrow BJ, Jurcisek JA, Stellato TA, Pretlow TP (1990) Aberrant crypts in the colons of humans and carcinogen-treated rats are enzyme-altered. Proc Am Assoc Cancer Res 31:85
21. Peraino C, Richards WL, Stevens FJ (1983) Multistage hepatocarcinogenesis. In Slaga TJ, ed. Mechanisms of Tumor Promotion. Vol 1. Boca Raton, FL, CRC Press, 1-53
22. Pereira MA, Barnes LH, Rassman VL, Kelloff GV, Steele VE (1994) Use of azoxymethane-induced foci of aberrant crypts in rat colon to identify potential cancer chemopreventive agents. Carcinogenesis 15:1049-1054
23. Pitot HC (1981) Fundamentals of Oncology. 2nd ed. New York, Dekker
24. Pretlow TG, Nagabhushan M, Pretlow TP (1995) Prostatic intraepithelial neoplasia and other changes during promotion and progression. Pathol Res Pract 191:842-849
25. Pretlow TG, Nagabhushan M, Sy M, Guo Y, Pretlow TP (1994a) Putative preneoplastic foci in the human prostate. J Cell Biochem Suppl 19:224-231
26. Pretlow TP (1994) Alterations associated with early neoplasia in the colon. In Pretlow TG, Pretlow TP, eds. Biochemical and Molecular Aspects of Selected Cancers. Vol 2. San Diego, Academic Press, 93-141
27. Pretlow TP, Barrow BJ, Ashton WS, O'Riordan MA, Pretlow TG, Jurcisek JA, Stellato TA (1991) Aberrant crypts: putative preneoplastic foci in human colonic mucosa. Cancer Res 51:1564-1567
28. Pretlow TP, Brasitus TA, Fulton NC, Cheyer C, Kaplan EL (1993a) K-ras mutations in putative preneoplastic lesions in human colon. J Natl Cancer Inst 85:2004-2007
29. Pretlow TP, Cheyer C, O'Riordan MA (1994b) Aberrant crypt foci and colon tumors in F344 rats have similar increases in proliferative activity. Int J Cancer 56:599-602
30. Pretlow TP, Grane RW, Goehring PL, Lapinsky AS, Pretlow TG (1987) Examination of enzyme-altered foci with gamma-glutamyl transpeptidase, aldehyde dehydrogenase, glucose-6-phosphate dehydrogenase, and other markers in methacrylate-embedded liver. Lab Invest 56:96-100
31. Pretlow TP, O'Riordan MA, Kolman MF, Jurcisek JA (1990) Co-Ionic aberrant crypts in azoxymethane-treated F344 rats have decreased hexosaminidase activity. Am J Pathol 136:13-16
32. Pretlow TP, O'Riordan MA, Pretlow TG, Stellato TA (1992a) Aberrant crypts in human colonic mucosa: putative preneoplastic lesions. J Cell Biochem Suppl 16G:55-62
33. Pretlow TP, O'Riordan MA, Somich GA, Amini SB, Pretlow TG (1992b) Aberrant crypts correlate with tumor incidence in F344 rats treated with azoxymethane and phytate. Carcinogenesis 13:1509-1512
34. Pretlow TP, O'Riordan MA, Spancake KM, Pretlow TG (1993b) Two types of putative preneoplastic lesions identified by hexosaminidase activity in whole-mounts of colons from F344 rats treated with carcinogen. Am J Pathol 142:1695-1700
35. Pretlow TP, Pretlow TG (1997) Neoplasia and preneoplasia of the intestines. In Bannasch P, Gössner W, eds. Pathology of Neoplasia and Preneoplasia in Rodents. EULEP Color Atlas of Pathology. Vol 2. New York, FK Schattauer, 75-94
36. Pretlow TP, Roukhadze E, O'Riordan MA, Chan JC, Amini SB, Stellato TA (1994c) Carcinoembryonic antigen in human colonic aberrant crypt foci. Gastroenterology 107:1719-1725
37. Rabes HM (1983) Development and growth of early preneoplastic lesions induced in the liver by chemical carcinogens. J Cancer Res Clin Oncol 106:85-92
38. Roncucci L, Medline A, Bruce WR (1991a) Classification of aberrant crypt foci and microadenomas in human colon. Cancer Epidemiol Biomarkers Prev 1:57-60
39. Roncucci L, Stamp D, Medline A, Cullen JB, Bruce WR (1991b) Identification and quantification of aberrant crypt foci and microadenomas in the human colon. Hum Pathol 22:287-294
40. Scherer E, Hoffmann M (1971) Probable clonal genesis of cellular islands induced in rat liver by diethylnitrosamine [Letter]. Eur J Cancer 7:369-371
41. Shi S-R, Cote RJ, Taylor CR (1997) Antigen retrieval immunohistochemistry: past, present, and future. J Histochem Cytochem 45:327-343
42. Shi SR, Key ME, Kalra KL (1991) Antigen retrieval in fromalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. J Histochem Cytochem 39:741-748
43. Shivapurkar N, Tang Z, Ferreira A, Nasim S, Garett C, Alabaster O (1994) Sequential analysis of K-ras mutations in aberrant crypt foci and colonic tumors induced by azoxymethane in Fischer-344 rats on high-risk diet. Carcinogenesis 15:775-778
44. Singh J, Kulkarni N, Kelloff G, Reddy BS (1994) Modulation of azoxymethane-induced mutational activation of ras protooncogenes by chemopreventive agents in colon carcinogenesis. Carcinogenesis 15:1317-1323
45. Siu I-M, Pretlow TG, Amini SB, Pretlow TP (1997) Identification of dysplasia in human colonic aberrant crypt foci. Am J Pathol 150:1805-1813
46. Smith AJ, Stern HS, Penner M, Hay K, Mitri A, Bapat BV, Gallinger S (1994) Somatic APC and K-ras codon 12 mutations in aberrant crypt foci from human colons. Cancer Res 54:5527-5530
47. Stopera SA, Murphy LC, Bird RP (1992) Evidence for a ras gene mutation in azoxymethane-induced colonic aberrant crypts in Sprague-Dawley rats: earliest recognizable precursor lesions of experimental colon cancer. Carcinogenesis 13:2081-2085
48. Wargovich MJ, Chen CD, Harris C, Yang E, Velasco M (1995) Inhibition of aberrant crypt growth by non-steroidal anti-inflammatory agents and differentiation agents in the rat colon. Int J Cancer 60:515-519
49. Wargovich MJ, Chen C-D, Jimenez A, Steele VE, Velasco M, Stephens LC, Price R, Gray K, Kelloff GJ (1996) Aberrant crypts as a biomarker for colon cancer: evaluation of potential chemopreventive agents in the rat. Cancer Epidemiol Biomarkers Prev 5:355-360
50. Weber G (1977) Enzymology of cancer cells. N Engl J Med 296:486-493, 541-551
51. Yamashita N, Minamoto T, Ochia A, Onda M, Esumi H (1995) Frequent and characteristic K-ras activation and absence of p53 protein accumulation in aberrant crypt foci of colon. Gastroenterology 108:434-440
52. Zaidi NH, Pretlow TP, O'Riordan MA, Dumenco LL, Allay E, Gerson SL (1995) Transgenic expression of human MGMT protects against azoxymethane induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon. Carcinogenesis 16:451-456