The effect of ethanol and its metabolites upon methionine synthase activity in vitro

Alcohol

Volumn 15, Issue 4, 1998, Pages 305-309

  Kenyon, Susan H ^a   Nicolaou, Anna ^b   Gibbons, William A ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

Acetaldehyde; Cobalamin; Ethanol; Homocysteine; Methionine; Methionine synthase

Indexed keywords

ACETALDEHYDE; ACETIC ACID ETHYL ESTER; ALCOHOL; LIVER ENZYME; METHIONINE SYNTHASE;

ALCOHOL INTOXICATION; ALCOHOL METABOLISM; ALCOHOLISM; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PURIFICATION; LIVER TOXICITY; MACROCYTIC ANEMIA; NONHUMAN; RAT;

5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE S-METHYLTRANSFERASE; ACETALDEHYDE; ACETATES; ANIMALS; ETHANOL; OSMOLAR CONCENTRATION; RATS; TIME FACTORS;

EID: 0031949104     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-8329(97)00134-1     Document Type: Article

References (31)

1. Allen R. H., Stabler S. P., Savage D. G., Lindenbaum J. Metabolic abnormalities in cobalamin and folate deficiency. FASEB J. 7:1993;1344-1353.
2. Banerjee R. V., Matthews R. G. Cobalamin-dependent methionine synthase. FASEB J. 4:1990;1450-1459.
3. Barak A. J., Beckenbauer H. C., Tuma D. J. Hepatic transmethylation and blood alcohol levels. Alcohol Alcohol. 26:1991;125-128.
4. Barak A. J., Beckenbauer H. C., Junmila M., Tuma D. J. Dietary betaine promotes generation of hepatic S-adenosyl-L-methionine and protects the liver from ethanol-induced fatty infiltration. Alcohol. Clin. Exp. Res. 17:1993;552-565.
5. Bradford M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-252.
6. Chanarin I., Deacon R., Lumb M., Perry J. Cobalamin-folate. Recent developments J. Clin. Pathol. 45:1992;277-283.
7. Eriksson C. J. P., Sippel H. W. The distribution and metabolism of acetaldehyde in rat during ethanol oxidation 1. The distribution of acetaldehyde in liver, brain, blood and breath Biochem. Pharmacol. 26:1977;241-247.
8. 12 and folate function in chronic alcoholic men with peripheral neuropathy and encephalopathy. J. Nutr. 119:1989;416-424.
9. 12. 1990;London Childrens Medical Charity, London.
10. Gulati S., Baker P., Li Y. N., Fowler B., Kruger W., Brody L. C., Banerjee R. Defects in human methionine synthase in cbl G patients. Hum. Mol. Gen. 5:1996;1859-1865.
11. Hidiroglou N., Camilo M. E., Beckenhauer H. C., Tuma D. J., Barak A. J., Nixon P. F., Selhub J. Effect of chronic alcohol ingestion on hepatic folate distribution in the rat. Biochem. Pharmacol. 47:1994;1561-1566.
12. Hoffman R. M. Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. Biochem. Biophys. Acta. 738:1984;49-87.
13. Hoffman T., Meyer R. J., Sorell M. F., Tuma D. J. Reaction of acetaldehyde with proteins. Formation of stable fluorescent adducts Alcohol. Clin. Exp. Res. 17:1993;69-74.
14. 12 levels in serum and cerebrospinal fluid of people with Alzheimer's disease. Acta Psychiatr. Scand. 82:1990;327-329.
15. Israel Y., Orrego H., Carmichael F. J. Acetate-mediated effects of ethanol. Alcohol. Clin. Exp. Res. 18:1994;144-148.
16. 12-dependent methionine synthase by polyamines. Biochem. J. 316:1996;661-665.
17. 12 and folate status in rats after chronic administration of ethanol and acute exposure to nitrous oxide. Alcohol. Clin. Exp. Res. 15:1991;543-548.
18. Koblin D. D., Tomerson B. W. Methionine synthase activities in mice following acute exposures to ethanol and nitrous oxide. Biochem. Pharmacol. 38:1989;1353-1358.
19. Klysosov A. A., Rashkovetsky L. G., Tahir M. K., Keung W. M. Possible role of liver cytosolic and mitochondrial acetaldehyde dehydrogenases in acetaldehyde metabolism. Biochemistry. 35:1996;4445-4456.
20. Lindenbaum J. Haematological complications of alcohol abuse. Semin. Liver Dis. 7:1987;169-181.
21. Lieber C. S. Interaction of alcohol and other drugs and nutrients. Implication for the therapy of alcoholic liver disease. Drugs. 40(Suppl. 3):1990;23-44.
22. McCully K. S. Homocysteine and vascular disease. Nature Med. 2:1996;386-389.
23. Nicolaou A., Kenyon S. H., Gibbons J. M., Ast T., Gibbons W. A. In vitro inactivation of mammalian methionine synthase by nitric oxide. Eur. J. Clin. Invest. 26:1996;167-170.
24. Nicolaou A., Waterfield C. J., Kenyon S. H., Gibbons W. A. The inactivation of methionine synthase in isolated rat hepatocytes by sodium nitroprusside. Eur. J. Biochem. 244:1997;876-882.
25. Pietrzak E. R., Shanley B. C., Kroon P. A. Antibodies made against a formaldehyde-protein adduct cross-react with an acetaldehyde-protein adduct. Implications for the origin of antibodies in human serum which recognise acetaldehyde-protein adducts. Alcohol Alcohol. 30:1995;373-378.
26. 12 metabolism in multiple sclerosis. Arch. Neurol. 49:1992;649-652.
27. Scott J. M., Kirke P. N., Weir D. G. The role of nutrition in neural tube defects. Annu. Rev. Nutr. 10:1990;277-295.
28. Sherif F., Gomes C., Oreland L. Methionine synthase and methionine adenosyltransferase activities in rat brain after ethanol treatment. Pharmacol. Toxicol. 73:1993;287-290.
29. Trimble K. C., Molloy A. M., Scott J. M., Weir D. G. The effect of ethanol on one-carbon metabolism. Increased methionine catabolism and lipotrope methyl-group wastage Hepatology. 18:1993;984-989.
30. Wang J. F., Greenberg S. S., Spitzer J. J. Chronic alcohol administration stimulates nitric oxide formation in the rat liver with and without pretreatment by lipopolysaccharide. Alcohol. Clin. Exp. Res. 19:1995;387-393.
31. Weissbach H., Peterkofsky A., Redfield B. G., Dickerman H. Studies on the terminal reaction in the biosynthesis of methionine. J. Biol. Chem. 238:1963;3318-3324.