Serum concentrations of clozapine and N-desmethylclozapine are unaffected by the potent CYP3A4 inhibitor itraconazole

European Journal of Clinical Pharmacology

Volumn 54, Issue 2, 1998, Pages 167-170

  Raaska, K ^a   Neuvonen, P J ^b  

^a Kellokoski Hospital   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Clozapine; Itraconazole

Indexed keywords

CLOZAPINE; ITRACONAZOLE; NORCLOZAPINE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG METABOLISM; FEMALE; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCHIZOPHRENIA; ULTRAVIOLET SPECTROPHOTOMETRY;

ADULT; ANTIFUNGAL AGENTS; ANTIPSYCHOTIC AGENTS; CLOZAPINE; CYTOCHROME P-450 ENZYME SYSTEM; DOUBLE-BLIND METHOD; DRUG INTERACTIONS; FEMALE; HUMANS; ITRACONAZOLE; MALE; MIXED FUNCTION OXYGENASES; SCHIZOPHRENIA;

EID: 0031948562     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050440     Document Type: Article

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