Autologous stem-cell transplantation for non-Hodgkin's lymphomas: The role of graft purging and radiotherapy posttransplantation - Results of a retrospective analysis on 120 patients autografted in a single institution

Journal of Clinical Oncology

Volumn 16, Issue 8, 1998, Pages 2803-2816

  Fouillard, L ^a   Laporte, J P ^b   Labopin, M ^b   Lesage, S ^b   Isnard, F ^b   Douay, L ^b   Lopez, M ^b   Aoudjhane, M ^b   Zunic, P ^b   Cheron, N ^b   Stachowiak, J ^b   Lemonnier, M P ^b   Andreu, G ^b   Belkacemi, Y ^b   Noel Walter M P ^b   Morel, P ^b   Fenaux, P ^b   Jouet, J P ^b   Bauters, F ^b   Najman, A ^b   Gorin, N C ^b   more..

^a HÔPITAL SAINT ANTOINE   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CARMUSTINE; CD34 ANTIGEN; CYTARABINE; ETOPOSIDE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; MAFOSFAMIDE; MELPHALAN;

ADULT; ARTICLE; BONE MARROW PURGING; CANCER COMBINATION CHEMOTHERAPY; CANCER GRADING; CANCER RADIOTHERAPY; CANCER REGRESSION; CANCER SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; MALE; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; TREATMENT OUTCOME; WHOLE BODY RADIATION;

EID: 0031948106     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1998.16.8.2803     Document Type: Article

References (51)

1. Barlett NL, Rizeq M, Dorfman RF, et al: Follicular large-cell lymphoma: Intermediate or low grade? J Clin Oncol 12:1349-1357, 1994
2. Philip T, Guglielmi C, Hagenbeck A, et al: Autologous bone marrow transplantation as compared with salvage chemotherapy in relapses of chemotherapy-sensitive non-Hodgkin's lymphoma. N Engl J Med 333:1540-1544, 1995
3. Philip T, Armitago JO, Spitzer G, et al: High-dose therapy and autologous bone marrow transplantation after failure of conventional chemotherapy in adults with intermediate grade or high-grade non-Hodgkin's lymphoma. N Engl J Med 3:1493-1498, 1987
4. Haioun C, Lepage E, Gisselbrecht C, et al: A GELA study: Autologous transplantation versus conventional salvage therapy in aggressive non-Hodgkin's lymphoma partially responding to first line chemotherapy. A study of 96 patients enrolled in the LNH87-2 protocol. Blood 86:211a, 1995(supp 1, abstr)
5. Haioun C, Lepage E, Gisselbrecht C, et al: A GELA study: Autologous bone marrow transplantation versus sequential chemotherapy for aggressive non-Hodgkin's lymphoma in first complete remission: A study of 542 patients (LHN87-2 protocol). Bone Marrow Transplant 17:5144, 1996(suppl 1)
6. Reyes F, Lepage E, Morel P, et al: Failure of first line high-dose chemotherapy in poor risk patients with aggressive lymphoma: Updated results of the randomized LNH93-3 study. Blood 90:594a, 1997 (suppl 1, abstr)
7. Rohatiner AZS, Johnson PWM, Price CGA, et al: Myeloablative therapy with autologous bone marrow transplantation as consolidation therapy for recurrent follicular lymphoma. J Clin Oncol 12:1177-1184, 1994
8. Cervantes F, Shu XO, McGlave PB, et al: Autologous bone marrow transplantation for non-transformed low-grade non-Hodgkin's lymphoma. Bone Marrow Transplant 16:387-392, 1995
9. Freedman AS, Ritz J, Neuberg D, et al: Autologous bone marrow transplantation in 69 patients with a history of low-grade B-cell non-Hodgkin's lymphoma. Blood 77:2524-2529, 1991
10. Colombat P, Donadio D, Fouillard L, et al: Value of autologous bone marrow transplantation in follicular lymphoma: A France-Autogreefe retrospective study of 42 patients. Bone Marrow Transplant 13:157-162, 1994
11. Schouten HC, Bierman PJ, Vaughan WP, et al: Autologous bone marrow transplantation in follicular non-Hodgkin's lymphoma before and after histological transformation. Blood 74:2579-2584, 1989
12. Fouillard L, Gorin NC, Laporte JP, et al: Feasibility of autologous bone marrow transplantation for early consolidation of follicular non-Hodgkin's lymphoma. Eur J Haematol 46:279-284, 1991
13. Haas R, Murea S, Moos, et al: High-dose therapy with peripheral blood stem cell transplantation in low-grade non-Hodgkin's lymphomas. Blood 88:120a, 1996 (suppl 1, abstr)
14. Freedman AS, Gribben JG, Neuberg D, et al: High-dose therapy and autologous bone marrow transplantation in patients with follicular lymphoma during first remission. Blood 88:2780-2786, 1996
15. Linassier C, Fouillard L, Milpied N, et al: Value of autologous bone marrow transplantation in 42 patients with follicular lymphomas responsive to conventional chemotherapy: A 〈〈France autogreffe〉〉 study. Cancer Direct Prev 20:11-19, 1996
16. Morel P, Laporte JPh, Noel MP, et al: Autologous bone marrow transplantation as consolidation therapy may prolong remission in newly diagnosed high-risk follicular lymphoma: A pilot study of 34 cases. Leukemia 9:576-582, 1995
17. Laporte J.Ph, Douay L, Lopez M, et al: One hundred twenty-five adult patients with primary acute leukemia autografted with marrow purged by mafosfamide a 10-year single institution experience. Blood 84:3810-3818, 1994
18. Gorin NC, Aegerter P, Auvert B, et al: Autologous bone marrow transplantation for acute myelocytic leukemia in first remission: A European survey of the role of marrow purging. Blood 75:1606-1614, 1990
19. Gorin NC, Labopin M, Meloni G, et al: Autologous bone marrow transplantation for acute myeloblastic leukemia in Europe: further evidence of the role of marrow purging by mafosfamide. Leukemia 5:896-904, 1991
20. Brenner M, Rill DR, Moen RC, et al: Gene-marking to trace origin of relpase after autologous bone marrow transplantation. Lancet 341:85-86, 1993
21. Deisseroth AB, Zu Z, Claxton D, et al: Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML. Blood 83:3068-3076, 1994
22. Gribben JG, Freedman AS, Neuberg D, et al: Immunologic purging of marrow assessed by PCR before autologous bone marrow transplantation for B-cell lymphoma. N Engl J Med 325:1525-1533, 1991
23. Gribben JG, Neuberg D, Freedman AS, et al: Detection by polymerase chain reaction of residual cells with the bcl-2 translocation is associated with increased risk of relapse after autologous bone marrow transplantation for B-cell lymphoma. Blood 81:3449-3457, 1993
24. Williams CD, Goldstone AH, Pearce RM, et al: Purging of bone marrow in autologous bone marrow transplantation for non-Hodgkin's lymphoma: A case-matched comparison with unpurged cases by the European Blood and Marrow Transplant Lymphoma Registry. J Clin Oncol 14:2454-2464, 1996
25. Sharp JG, Kessinger A, Mann S, et al: Outcome of high-dose therapy and autologous transplantation in non-Hodgkin's lymphoma based on the presence of tumor in the marrow or infused hematopoietic harvest. J Clin Oncol 14:214-219, 1996
26. The International Non-Hodgkin's Lymphoma Prognostic Project: A predictive model for aggressive non-Hodgkin's lymphoma. N Engl J Med 329:987-994, 1993
27. Non-Hodgkin's Lymphoma Pathologic Classification Project: National Cancer Institute sponsored formulation for clinical usage. Cancer 49:2112-2135, 1982
28. Gorin NC, Douay L, Laporte JP, et al: Autologous bone marrow transplantation using marrow incubated with Asia Z-7557 in adult acute leukemia. Blood 67:1367-1376, 1986
29. Douay L, Gorin NC, Laporte JPh, et al: Asta Z-7557 (INN mafosfamide) for the in vitro treatment of human leukemic bone marrow. Invest New Drugs 2:187-190, 1984
30. Lopez M, Dupuy-Montbrun MC, Douay L, et al: Standardization and characterization of the procedure for in vitro treatment of human bone marrow with cyclophosphamide derivatives. Clin Lab Haematol 7:327-334, 1985
31. Douay L, Mary JY, Giarratana MC, et al: Establishment of a reliable experimental procedure for autologous bone marrow purging with mafosfamide (Asta Z-7557). Exp Hematol 17:429-432, 1989
32. + bone marrow progenitor cells in patients with non-Hodgkin's lumphoma. Blood 85:1647-1654, 1995
33. Gorin NC, Coiffier B, Hayat M, et al: Recombinant human granulocyte-macrophage colony-stimulating factor after high-dose chemotherapy and autologous bone marrow transplantation with unpurged and purged marrow in non-Hodgkin's lymphoma: A double-blind placebo controlled trial. Blood 80:1149-1157, 1992
34. Colombat Ph, Gorin NC, Lemonnier MP, et al: The role of autologous bone marrow transplantation in 46 adult patients with non-Hodgkin's lymphomas. J Clin Oncol 8:630-637, 1990
35. Attal M, Canal P, Schlaifer D, et al: Escalating dose of mitoxantrone with high-dose cyclophosphamide, carmustine, and etoposide in patients with refractory lymphoma undergoing autologous bone marrow transplantation. J Clin Oncol 12:141-148, 1994
36. Nademanee A, Schmidt GH, O'Donnell MR, et al: High-dose chemotherapy followed by autologous bone marrow transplantation as consolidation therapy during first complete remission in adult patients with poor risk aggressive lymphoma: A pilot study. Blood 80:1130-1134, 1992
37. Freedman AS, Takvorian T, Neuberg D, et al: Autologous bone marrow transplantation in poor prognosis intermediate grade and high-grade B-cell non-Hodgkin's lymphoma in first remission: A pilot study. J Clin Oncol 11:931-936, 1993
38. Nademanee A, Molina A, O'Donnell M, et al: High-dose therapy and autologous bone marrow/stem cell transplantation as consolidation therapy during first CR/PR in patients with poor-risk intermediate and high-grade lymphoma. Blood 88:684a, 1996 (suppl 1, abstr)
39. Verdonck LF, Van Putten WLJ, Hagenbeek A, et al: Comparison of CHOP chemotherapy with autologous bone marrow transplantation for slowly responding patients with aggressive non-Hodgkin's lymphoma. N Engl J Med 332:1045-1051, 1995
40. Lopez-Guillermo A, Montserrat E, Bosh F, et al: Applicability of the international index for aggressive lymphomas to patients with low-grade lymphoma. J Clin Oncol 12:1343-1348, 1994
41. Vaughan-Hudson B, Vaughan-Hudson G, MacLennan KA, et al: Clinical stage 1 non-Hodgkin's lymphoma: Long-term follow-up of patients treated by the British National Lymphoma Investigation with radiotherapy alone as initial therapy. Br J Cancer 69:1088-1093, 1994
42. MacManus MP, Hoppe RT: Is radiotherapy curative for stage I and II low-grade follicular lymphoma? Results of long-term follow-up study of patients treated at Stanford University. J Clin Oncol 14:1282-1290, 1996
43. Lee CK, Levitt SH: Long-term follow-up of pathologic stage I large cell non-Hodgkin's lymphoma patients after primary radiotherapy. Am J Clin Oncol 19:93-98, 1996
44. Lambertenghi-Deliliers G, Butti C, Baldini L, et al: A cooperative study of epirubicin with cyclophosphamide, vincristine and prednisone (CEOP) in non-Hodgkin's lymphoma. Haematologica 80:318-324, 1995
45. Tondini C, Zanini M, Lombardi F, et al: Combined modality treatment with primary CHOP chemotherapy followed by locoregional irradiation in stage I or II histologically aggressive non-Hodgkin's lymphomas. J Clin Oncol 11:720-725, 1993
46. Silingardi V, Federico M, Cavanna L, et al: ProMECE-CytaBOM vs MACOB-B in advanced aggressive non-Hodgkin's lymphoma: Long-term results of a multicenter study of the Italian Lymphoma Study Group (GISL). Leuk Lymphoma 17:313-320, 1995
47. Bergmann L, Karakas T, Lautenschlager G, et al: Vincristine, doxorubicin, cyclophosphamide. prednisone and etoposide (VACPE) in high-grade non-Hodgkin's lymphoma: A multicenter phase II study. Ann Oncol 6:1019-1024, 1995
48. Philips GL, Fay JW, Herzig RH, et al: The treatment of progressive non-Hodgkin's lymphoma with intensive chemoradiotherapy and autologous marrow transplantation. Blood 75:831-838, 1990
49. Rapoport AP, Rowe JM, Kouides PA, et al: One hundred autotransplants for relapsed or refractory Hodgkin's disease and lymphoma: Value of pretransplant disease status for predicting outcome. J Clin Oncol 11:2351-2361, 1993
50. Rowley SD, Jones RJ, Piantadosi S, et al: Efficacy of ex vivo purging for autologous bone marrow transplantation in the treatment of acute non-lymphoblastic leukemia. Blood 74:501-506, 1989
51. Laporte JP, Karakassis D, Lesage S, et al: Can hematopoietic growth factors replace autologous bone marrow transplantation in lymphoma patients when tumoral marrow infiltration precludes it. Blood 86:439a, 1995 (suppl 1, abstr)