Inhibition of calcium-activated chloride channels by niflumic acid dilates rat cerebral arteries

Acta Physiologica Scandinavica

Volumn 163, Issue 4, 1998, Pages 417-418

  Robertson, B E ^a,b  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

^b BAYER CORPORATION   (United States)

Author keywords

Calcium activated chloride channels; Niflumic acid; Vascular smooth muscle

Indexed keywords

CALCIUM; CHLORIDE CHANNEL; NIFLUMIC ACID;

ANIMAL EXPERIMENT; BRAIN ARTERY; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; SHORT SURVEY; VASODILATATION;

EID: 0031948105     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.1998.t01-1-00366.x     Document Type: Short Survey

References (6)

1. Brayden, J.E. & Nelson, M.T. 1992. Regulation of arterial tone by activation of calcium-dependent potassium channels. Science 256, 532-535.
2. Greenwood, I.A. & Large, W.A. 1995. Comparison of the effects of fenamates on Ca-activated chloride and potassium currents in rabbit portal vein smooth muscle cells. Br J Pharmacol 116, 2939-2948.
3. Lamb, F.S., Volk, K.A. & Shibata, E.F. 1994. Calcium-activated chloride current in rabbit coronary artery myocytes. Circ Res 75, 742-750.
4. 2+-activated chloride conductance in smooth muscle. Am J Physiol 271, C435-C454.
5. Nelson, M.T., Conway, M.A., Knot, H.J. & Brayden, J.E. 1997. Chloride channel blockers inhibit myogenic tone in rat cerebral arteries. J Physiol 502, 259-264.
6. ca channels by niflumic, flufenamic, and mefenamic acids. Biophys J 67, 2272-2279.