Albendazole for treatment and prophylaxis of microsporidiosis due to Encephalitozoon intestinalis in patients with AIDS: A randomized double- blind controlled trial

Journal of Infectious Diseases

Volumn 177, Issue 5, 1998, Pages 1373-1377

  Molina, Jean Michel ^a   Chastang, Claude ^b   Goguel, Jérome ^b   Michiels, Jean François ^b   Sarfati, Claudine ^b   Desportes Livage, Isabelle ^b   Horton, John ^b   Derouin, Francis ^b   Modaï, Jacques ^b  

^a SAINT LOUIS HOSPITAL   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALBENDAZOLE; PLACEBO;

ABDOMINAL PAIN; ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; ENCEPHALITOZOON INTESTINALIS; FEMALE; FEVER; HEADACHE; HUMAN; HUMAN TISSUE; MALE; MICROSPORA; MICROSPORIDIOSIS; OPPORTUNISTIC INFECTION; PNEUMONIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RELAPSE; THROMBOCYTOPENIA;

EID: 0031946849     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/515268     Document Type: Article

References (13)

1. Cali A, Kotler DP, Orenstein JM. Septata intestinalis N. G., N. Sp., an intestinal microsporidian associated with chronic diarrhea and dissemination in AIDS patients. J Eukaryot Microbiol 1993;40:101-12.
2. Hartskeerl RA, Van Gool T, Schuitema ARJ, Didier ES, Terpstra WJ. Genetic and immunological characterization of the microsporidian Septata intestinalis Cali, Kotler and Orenstein: reclassification to Encephalitozoon intestinalis. Parasitology 1995; 110:277-85.
3. Orenstein JM, Dieterich DT, Lew AE, Kotler D. Albendazole as a treatment for intestinal and disseminated microsporidiosis due to Septata intestinalis in AIDS patients: a report of four patients. AIDS 1993; 7(suppl 3):S40-2.
4. Molina JM, Oksenhendler E, Beauvais B, et al. Disseminated microsporidiosis due to Septata intestinalis in patients with AIDS: clinical features and response to albendazole therapy. J Infect Dis 1995; 171:245-9.
5. Gunnarsson G, Hurlbut D, DeGirolami P, Federman M, Wanke C. Multiorgan microsporidiosis: report of five cases and review. Clin Infect Dis 1995;21:37-44.
6. Weber R, Bryan RT, Owen RL, Poles MA, Orenstein JM. Improved light-microscopical detection of microsporidia spores in stools and duodenal aspirates. N Engl J Med 1991;326:161-6.
7. Van Gool T, Snijders F, Reiss P, et al. Diagnosis of intestinal and disseminated microsporidial infections in patients with HIV by a new rapid fluorescence technique. J Clin Pathol 1993 46:694-9.
8. Beauvais B, Sarfati C, Molina JM, Lesourd A, Lariviere M, Derouin F. Comparative evaluation of five diagnostic methods for demonstration of microsporidia in stools and intestinal biopsy specimen. Ann Trop Med Parasitol 1993;87, 1:99-102.
9. David F, Schuitema ARJ, Sarfati C, et al. Species identification of intestinal microsporidia by polymerase chain reaction in duodenal biopsies from human immunodeficiency virus-infected patients. J Infect Dis 1996; 174:874-7.
10. Liguory O, David F, Sarfati C, et al. Diagnosis of infections caused by Enterocytozoon bieneusi and Encephalitozoon intestinalis using PCR in stool specimens. AIDS 1997; 11:723-6.
11. Weber R, Sauer B, Spycher MA, et al. Detection of Septata intestinalis in stool specimens and coprodiagnostic monitoring of successful treatment with albendazole. Clin Infect Dis 1994; 19:342-5.
12. Dore GJ, Marriott DJ, Hing MC, Harkness JL, Field AS. Disseminated microsporidiosis due to Septata intestinalis in nine patients infected with the human immunodeficiency virus: response to therapy with albendazole. Clin Infect Dis 1995; 21:70-6.
13. Franzen C, Muller A, Schwenk A, et al. Intestinal microsporidiosis due to Septata intestinalis in a patient with AIDS-response to albendazole. J Infect 1995;31:237-9.