Immunohistological localization of the MrkD adhesin in the type 3 fimbriae of Klebsiella pneumoniae

Infection and Immunity

Volumn 66, Issue 5, 1998, Pages 2356-2361

  Tarkkanen, Ann Mari ^a   Westerlund Wikström, Benita ^a   Erkkilä, Leena ^a   Korhonen, Timo K ^a  

^a Div Microbiol PO Box 56 B   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; BACTERIAL PROTEIN; HYBRID PROTEIN; IMMUNOGLOBULIN; POLYCLONAL ANTIBODY;

ARTICLE; BACTERIAL GENE; BACTERIUM ADHERENCE; ESCHERICHIA COLI; FIMBRIA; GENE CLUSTER; GENE MUTATION; KLEBSIELLA PNEUMONIAE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN PURIFICATION;

ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE;

EID: 0031946843     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.5.2356-2361.1998     Document Type: Article

References (24)

1. Abraham, S. N., J. D. Goguen, U. Sun, P. Klemm, and E. H. Beachey. 1987. Identification of two ancillary subunits of Escherichia coli type 1 fimbriae by using antibodies against synthetic oligopeptides of fim gene products. J. Baetcriol. 169:5530-5536.
2. Coligan, J. H., A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober. 1994. Current protocols in immunology. John Wiley & Sons, Inc., New York, N.Y.
3. Duguid, J. P. 1959. Fimhriae and adhesive properties in Klebsiella strains. J. Gen. Microbiol. 21:271-286.
4. Gerlach, G.-F., and S. Clegg. 1988. Cloning and characterization of the gene cluster encoding type 3 (MR/K) fimbriac of Klebsiella pneumoniae. FEMS Microbiol. Lett. 49:377-383.
5. Gerlach, G.-F., and S. Clegg. 1988. Characterization of two genes encoding antigenically distinct type-1 fimbriae of Klebsiella pneumoniae. Gene 64: 231-240.
6. Gerlach, G.-F., B. L. Allen, and S. Clegg. 1988. Molecular characterization of the type 3 (MR/K) fimbriae of Klebsiella pneumoniae. J. Bacteriol. 170: 3547-3553.
7. Gerlach, G.-F., S. Clegg, and B. L. Allen. 1989. Identification and characterization of the genes encoding the type 3 and type 1 fimbrial adhesins of Klehsiella pneumoniae. J. Bacteriol. 171:1262-1270.
8. Hornick, D. B., B. L. Allen, M. A. Horn, and S. Clegg. 1992. Adherence to respiratory epithelia by recombinant Eschericlia colt expressing Klebsiella pneumoniae type 3 fimbrial gene products. Infect. Immun. 60:1577-1588.
9. Hornick, D. B., J. Thommandru, W. Smits, and S. Clegg. 1995. Adherence properties of an mrkD-negative mutant of Klebsiella pneumoniae. Infect. Immun. 63:2026-2032.
10. Hornick, D. B., B. L. Allen, M. A. Horn, and S. Clegg. 1991. Fimbrial types among respiratory isolates belonging to the family Enterobacteriaceae. J. Clin. Microbiol. 29:1795-1800.
11. Hultgren, S. J., S. Normark, and S. N. Abraham. 1991. Chaperone-assisted assembly and molecular architecture of adhesive pili. Annu. Rev. Microbiol. 45:383-415.
12. Jones, C. H., J. S. Pinkner, R. Roth, John Heuser, A. V. Nicholes, S. N. Abraham, and S. J. Hultgren. 1995. FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobucteriaceae. Proc. Natl. Acad. Sci. USA 92:2081-2085.
13. Korhonen, T. K., E.-L. Nurmiaho, H. Ranta, and C. Svanborg-Edén. 1980. New method for isolation of immunologically pure pili from Escherichia cali. Infect. Immun. 27:569-575.
14. Korhonen, T. K., E. Tarkka, H. Ranta, and K. Haahtela. 1983. Type 3 fimbriae of Klehsiella sp.: molecular characterization and role in bacterial adhesion to plant roots. J. Bacteriol. 155:860-865.
15. Krogfelt, K., H. Bergmans, and P. Klemm. 1990. Direct evidence that the FimH protein is the mannose-specific adhcsin of Escherichia coli type 1 fimhriae. Intect. Immun. 58:1995-1998.
16. Kuehn, M. J., J. Heuser, S. Normark, and S. Hultgren. 1992. P pili of uropathogenic Escherichia coli are composite fibres with distinct fibrillar adhesive tips. Nature 356:252-255.
17. Kunin, C. M. 1987. Detection, prevention, and management of urinary tract infections. Lea & Febiger, Philadelphia, Pa.
18. Lund, B., B.-I. Marklund, N. Strömberg, F. Lindberg, K.-A. Karlsson, and S. Normark. 1998. Uropathogenic Escherichia coli can express serologically identical pili of different receptor binding specificities. Mol. Microbiol. 2: 255-263.
19. Saarela, S., J. Tanskanen, N. Kalkkinen, B. Westerlund-Wikström, M. Rhen, and T. K. Korhonen. Unpublished data.
20. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1998. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
21. Schurtz, T. A., D. B. Hornick, T. K. Korhonen, and S. Clegg. 1994. The type 3 fimbrial adhesin gene (mrkD) is not conserved among all fimbriate strains. Infect. Immun. 62:4186-4191.
22. Tarkkanen, A.-M., B. L. Allen, B. Westerlund, H. Holthöfer, P. Kuusela, L. Risteli, S. Clegg, and T. K. Korhonen. 1990. Type V collagen as the target for type-3 fimbriae, enterobaclerial adherence organelles. Mol. Mierobiol. 4: 1353-1361.
23. Tarkkanen, A.-M., B. L. Allen, P. H. Williams, M. Kauppi, K. Haahtela, A. Siitonen, I. Ørskov, F. Ørskov, S. Clegg, and T. K. Korhonen. 1992. Fimbriation, capsulation, and iron-scavenging systems of Klebsiella strains associated with human urinary tract infection. Infect. Immun. 60:1187-1192.
24. Williams, P., and J. M. Tomas. 1990. The pathogenicity of Klebsiella pneumoniae. Rev. Med. Microbiol. 1:196-204.