Phorbol ester induces differentiation of a human prostatic cancer cell line TSU-Pr1 into cells with characteristics of microglia

Anticancer Research

Volumn 18, Issue 1 A, 1998, Pages 113-117

  Itayasu, Tomohiro ^a   Shimizu, Takahisa ^a   Iizumi, Tatsuo ^b   Oshio, Shigeru ^b   Umeda, Takashi ^b   Takeda, Ken ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b TEIKYO UNIVERSITY   (Japan)

Author keywords

Differentiation; Microglia; Phorbol ester; Prostate cancer; TSU Pr1

Indexed keywords

1 NAPHTHYL ACETATE ESTERASE; CELL MARKER; PHORBOL ESTER;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SHAPE; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MALE; MICROGLIA; PRIORITY JOURNAL; PROSTATE CANCER;

CELL DIFFERENTIATION; CELL DIVISION; HUMANS; LYMPHATIC METASTASIS; MACROPHAGE-1 ANTIGEN; MALE; MICROGLIA; NAPHTHOL AS D ESTERASE; PROSTATIC NEOPLASMS; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED;

EID: 0031945808     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. American Cancer Society, Cancer Facts and Figures-1991, p.5. Atlanta: American Cancer Society, 1991.
2. Huggins C and Hodges C: Studies on prostatic cancer. I. The effects of castration, of estrogen and androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res 1: 293-297, 1941.
3. Lepor H, Ross A and Walsh PC: The influence of hormonal therapy on survival of men with advanced prostatic cancer. J Urol 128: 335-340, 1982.
4. Bang YJ and Trepel JB: Terminal neuroendocrine differentiation of human prostate carcinoma cells in response to increased intracellular cyclic AMP. Proc Natl Acad Sci USA 91: 5330-5334,1994.
5. Takeda K, Minowada J and Bloch A: Kinetics of appearance of differentiation-associated characteristics in ML-1, a line of human myeloblastic leukemia cells, after treatment with 12-O-tetradecanoylphorbol-13-acetate, dimethyl sulfoxide, or 1-ß-D-arabinofuranosylcytosine. Cancer Res 42: 5152-5158, 1982.
6. Diamond L, O'Brien TG and Rovera G: Tumor promoters: effects on proliferation and differentiation of cells in culture. Life Sci 23: 1979-1988, 1978.
7. Koeffer HP, Bar-Eli M and Territo MC: Phorbol ester effect on differentiation of human myeloid leukemia cell lines blocked at different stages of maturation. Cancer Res 41: 919-926, 1981.
8. Lotem J and Sachs L: Regulation of normal differentiation in mouse and human myeloid leukemic cells by phorbol ester and the mechanism of tumor promotion. Proc Natl Acad Sci USA 76: 5158-5162, 1979.
9. Rovera G, Santoli D and Damsky C: Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with phorbol diesters. Proc Natl Acad Sci USA 76: 2779-2783, 1979.
10. Iizumi T and Koiso K: Establishment of a new prostatic carcinoma cell line (TSU-Pr1). J Urol 137: 1304-1306, 1987.
11. Yam LT, Li CY and Crosby WH: Cytochemical Identification of Monocytes and Granulocytes. Am J Clin Pathol 55: 283-290, 1971.
12. Tony WB, Christel D and Eugeen V: Generation and characterization of mouse microglial cell lines. J Neuroimmunology 52: 153-164, 1994.
13. Giulian D and Baker TJ: Characterization of ameboid microglia isolated from developing mammalian brain. J Neuroscience 6: 2163-2178, 1986.
14. 3 primes acute promyelocytic cells for TPA-induced monocytic differentiation through both PKC and tyrosine phosphorylation cascades. Exp Cell Res 222: 61-69, 1996.
15. 3 synergize 12-O-tetradecanoylphorbol-13-acetate to induce macrophage differentiation in acute promyelocytic leukemia NB4 cells. Leukemia 8: 1744-1749, 1994.
16. Aihara H, Asaoka Y, Yoshida K and Nishizuka, Y: Sustained activation of protein kinase C is essential to HL-60 cell differentiation to macrophage. Proc Natl Acad Sci USA 88: 11062-11066, 1991.
17. Macfarlane DE and Manzel L: Activation of beta-isozyme of protein kinase C (PKC beta) is necessary and sufficient for phorbol esterinduced differentiation of HL-60 promyelocytes. Studies with PKC-defective PET mutant. J Biol Chem 269: 4327-4331, 1994.
18. Ways DK, Qin W, Garris TO, Chen J, Hao E, Cooper DR, Usala SJ, Parker PJ and Cook PP: Effects of chronic phorbol ester treatment on protein kinase C activity, content, and gene expression in the human monoblastoid U937 cell. Cell Growth Differ 5: 161-169, 1994.