Expression of death-related genes and their relationship to loss of apoptosis in T1 ductal breast carcinomas

International Journal of Cancer

Volumn 79, Issue 2, 1998, Pages 103-110

  Sierra, Angels ^a   Castellsagué, Xavier ^a   Coll, Toni ^a   Mañas, Sandra ^a   Escobedo, Agustin ^a   Moreno, Abelardo ^a   Fabra, Angels ^a  

^a HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; BREAST CARCINOMA; CANCER GRADING; CAUSE OF DEATH; CELL SURVIVAL; DISEASE ASSOCIATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; REVIEW; TUMOR CLASSIFICATION;

EID: 0031944777     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19980417)79:2<103::AID-IJC1>3.0.CO;2-X     Document Type: Review

References (26)

1. BAKER, R.J. and NELDER, J.A., The GLIM system, release 3. Generalized linear interactive modeling, Numerical Algorithms Group, Oxford (1978).
2. BARGOU, R.C., DANIEL, P.T., MAPARA, M.Y., BOMMERT, K., WAGENER, C., KALLINICH, B., ROYER, H.D. and DÖRKEN, B., Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-α expression in tumor cells correlates with resistance towards apoptosis. Int. J. Cancer, 60, 854-859 (1995).
3. BEDI, A., PASRICHA, P.J., AKHTAR, A.J., BARBER, J.P., BEDI, G.C., GIARDIELLO, F.M., ZEHNBAUER, B.A., HAMILTON, S.R. and JONES, R.J., Inhibition of apoptosis during development of colorectal cancer. Cancer Res., 55, 1811-1816 (1995).
4. BINDER, C., MARX, D., BINDER, L., SCHAUER, A. and HIDDEMANN, W., Expression of Bax in relation to Bcl-2 and other predictive parameters in breast cancer. Ann. Oncol., 7, 129-133 (1996).
5. 2, and Bax in neuroendocrine lung tumors. Amer. J. Pathol., 149, 1941-1952 (1996).
6. BRESLOW, N.E. and DAY, N.E., Statistical methods in cancer research, Vol. 1. The analysis of case-control studies, IARC Scientific Publications 32, International Agency for Research on Cancer, Lyon (1980).
7. CECCARELLI, C., SANTINI, D., CHIECO, P., TAFFURELLI, M., MARRANO, D. and MANCINI, A.M., Multiple expression patterns of biopathological markers in primary invasive breast carcinoma: a useful tool for elucidating its biological behaviour. Ann. Oncol., 6, 275-282 (1995).
8. L promotes susceptibility to mutagenesis. Oncogene, 13, 1489-1497 (1996).
9. CHITTENDEN, T., HARRINGTON, E.A., O'CONNOR, R., FLEMINGTON, C., LUTZ, R.J., EVAN, G.I. and GUILD, B.C., Induction of apoptosis by the Bcl-2 homologue Bak. Nature (Lond.), 374, 733-736 (1995).
10. s gene therapy induces apoptosis of human mammary tumors in nude mice. Cancer Res., 56, 1965-1969 (1996).
11. FARROW, S.N. and BROWN, R., New members of the Bcl-2 family and their protein partners. Curr. Opinion Genet. Develop., 6, 45-49 (1996).
12. GAVRIELI, Y., SHERMAN, Y. and BEN-SASSON, S.A., Identification of programmed Cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol., 119, 493-501 (1992).
13. GAZZANIGA, P., GRADILONE, A., VERCILLO, R., GANDINI, O., SILVESTRINI, I., NAPOLITANO, M., ALBONICI, L., VICENZONI, A., GALLUCCI, M., FRATI, L. and AGLIANÓ, A.M., bcl-2/bax mRNA expression ratio as prognostic factor in low-grade urinary bladder cancer. Int. J. Cancer, 69, 100-104 (1996).
14. HALDAR, S., NEGRINI, M., MONNE, M., SABBIONI, S. and CROCE, C.M., Down-regulation of bcl-2 by p53 in breast cancer cells. Cancer Res., 54, 2095-2097 (1994).
15. KRAJEWSKA, M., KRAJEWSKI, S., EPSTEIN, J.I., SHABAIK, A., SAUVAGEOT, J., SONG, K., KITADA, S. and REED, J.C., Immunohistochemical analysis of bcl-2, bax, bcl-x, and mcl-1 expression in prostate cancers. Amer. J. Pathol., 148, 1567-1576 (1996).
16. KRAJEWSKI, S., BLOMQVIST, C., FRANSSILA, K., KRAJEWSKA, M., WASENIUS, V.-M., NISKANEN, E., NORDLING, S. and REED, J.C., Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma. Cancer Res., 55, 4471-4478 (1995).
17. KRAJEWSKI, S., KRAJEWSKA, M. and REED, J.C., Immunohistochemical analysis of in vivo patterns of Bak expression, a proapoptotic member of the Bcl-2 protein family. Cancer Res., 56, 2849-2855 (1996).
18. KRAJEWSKI, S., KRAJEWSKA, M., SHABAIK, A., MIYASHITA, T., WANG, H.G. and REED, J.C., Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2. Amer. J. Pathol., 145, 1323-1336 (1994a).
19. KRAJEWSKI, S., KRAJEWSKA, M., SHABAIK, A., WANG, H.G., IRIE, S., FONG, L. and REED, J.C., Immunohistochemical analysis of in vivo patterns of Bcl-x expression. Cancer Res., 54, 5501-5507 (1994b).
20. LIEBERMANN, D.A., HOFFMAN, B. and STEINMAN, R.A., Molecular controls of growth arrest and apoptosis: p53-dependent and independent pathways. Oncogene, 11, 199-210 (1995).
21. L. J. biol. Chem., 271, 6306-6312 (1996).
22. NIKIFOROV, M.A., HAGEN, K., OSSOVSKAYA, V.S., CONNOR, T.M.F., LOWE, S.W., DEICHMAN, G.I. and GUDKOV, A.V., p53 modulation of anchorage independent growth and experimental metastasis. Oncogene, 13, 1709-1719 (1996).
23. 1 breast cancer. Clin. Cancer Res., 2, 1887-1894 (1996).
24. SIERRA, A., LLOVERAS, B., CASTELLSAGUÉ, X., MORENO, L., GARCÍA-RAMIREZ, M. and FABRA, A., Bcl-2 expression is associated with lymph node metastasis in human ductal breast carcinoma. Int. J. Cancer, 60, 54-60 (1995).
25. S sensitizes MCF-7 cells to chemotherapy-induced apoptosis. Cancer Res., 55, 2507-2510 (1995).
26. YANG, E. and KORSMEYER, S.J., Molecular thanatopsis: a discourse on the Bcl-2 family and cell death. Blood, 88, 386-401 (1996).