Inhibitors of protein farnesylation 1998

Expert Opinion on Therapeutic Patents

Volumn 8, Issue 5, 1998, Pages 553-569

  Williams, T M ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

PFTase; Protein farnesyltransferase inhibitors; Protein prenylation; Protgein farnesyltransferase; Ras oncogene

Indexed keywords

2 [[2 [[2 [(2 AMINO 3 MERCAPTOPROPYL)AMINO] 3 METHYLPENTYL]OXY] 1 OXO 3 PHENYLPROPYL]AMINO] 4 (METHYLSULFONYL)BUTANOIC ACID ISOPROPYL ESTER; ANTINEOPLASTIC AGENT; BENZODIAZEPINE; BENZYLOXYCARBONYLHISTIDYL(O BENZYLTYROSYL)(O BENZYLSERYL)TRYPTOPHYL DEXTRO ALANINAMIDE; CISPLATIN; GGTI 298; HR 11; L 738749; LONAFARNIB; N (8 AMINO 2 BENZYL 5 ISOPROPYL 9 MERCAPTO 3,6 NONADIENOYL)METHIONINE; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; PROTEIN FARNESYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; RAS PROTEIN; RPR 113829; RPR 114334; TIPIFARNIB; UNCLASSIFIED DRUG;

CANCER THERAPY; DRUG DESIGN; ENZYME INHIBITION; HUMAN; KINETICS; LITERATURE; NONHUMAN; PATENT; RADIOSENSITIZATION; REVIEW; STRUCTURE ACTIVITY RELATION;

EID: 0031943826     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.8.5.553     Document Type: Review

References (73)