Effect of continuous enteral medium-chain fatty acid infusion on lipid metabolism in rats

Lipids

Volumn 33, Issue 3, 1998, Pages 261-266

  You, Yi Qian ^b   Ling, Pei Ra ^b   Qu, Zhensheng ^b   Bistrian, Bruce R ^a,b  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DECANOIC ACID; LONG CHAIN TRIACYLGLYCEROL; MEDIUM CHAIN FATTY ACID; MEDIUM CHAIN TRIACYLGLYCEROL; PALMITOLEIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; ENTERIC FEEDING; FATTY ACID BLOOD LEVEL; LIPID METABOLISM; LIPOGENESIS; MALE; NONHUMAN; PORTAL VEIN BLOOD; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; ARACHIDONIC ACID; DIETARY FATS; FATTY ACIDS; INFUSIONS, PARENTERAL; LINOLEIC ACID; LIPID METABOLISM; LIPIDS; LYMPH; MALE; RATS; RATS, SPRAGUE-DAWLEY; TRIGLYCERIDES;

EID: 0031943223     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11745-998-0204-z     Document Type: Article

References (21)

1. Bach, A.C., and Babayan, V.K. (1982) Medium-Chain Triglycerides: An Update, Am. J. Clin. Nutr. 36, 950-962.
2. Senior, J.R. (ed.) (1968) Medium-Chain Triglycerides, University of Pennsylvania Press, Philadelphia, pp. 3-7.
3. Christensen, M.S., Hoy, C.E., Becker, C.C., and Redgrave, T.G. (1995) Intestinal Absorption and Lymphatic Transport of Eicosapentaenoic Acid (EPA), Docosahexaenoic Acid (DHA) and Decanoic Acids: Dependence on Intramolecular Triacylglycerol Structure, Am. J. Clin. Nutr. 61, 56-61.
4. Pomposelli, J.J., Valicenti, A.J., Babayan, V.K., Hamawy, K.J., Bistrian, B.R., and Blackburn, G.L. (1984). Medium-Chain Triglycerides (MCT) Are Efficient Energy Sources in Hepatic Insufficiency, JPEN 8, 88.
5. McGandy, R.B., Hegsted, D.M., and Myers, M.L. (1970) Use of Semi-Synthetic Fats in Determining Effects of Specific Fatty Acids on Serum Lipids in Man, Am. J. Clin. Nutr. 23, 1288-1298.
6. Takase, S., and Hosoya, N. (1986). Effect of Dietary Medium-Chain Triglyceride on Lipogenic Enzyme Activity in Rat Liver, J. Nutr. Sci. Vitamin. 32, 219-227.
7. Hill, J.O., Peters, J.C., Swift, L.L., Yang, D., Sharp, T., Abumrad, N., and Greene, H.L. (1990) Changes in Blood Lipids During Six Days of Overfeeding with Medium or Long-Chain Triglycerides, J. Lipid Res. 31, 407-416.
8. Folch, J., Lees, M., and Stanley, S.G.H. (1957) A Simple Method for the Isolation and Purification of Total Lipids from Animal Tissues, J. Biol. Chem. 226, 497-509.
9. Vallot, A., Bernards, A., and Carlier, H. (1985) Influence of the Diet on the Portal and Lymph Transport of Decanoic Acid in Rats. Simultaneous Study of Its Mucosal Catabolism, Comp. Biochem. Physiol. A: Comp. Physiol. 82, 693-696.
10. Bougneres, P.F., Castano, L., Rocchiccioli, F., Gia, H.P., Leluyer, B., and Ferre, P. (1989) Medium-Chain Fatty Acids Increase Glucose Production in Normal and Low Birth Weight Newborns, Am. J. Physiol. 256, E692-697.
11. Rabinowitz, J.L., Staeffeu, J., Aumonier, P., Ballan, P., Ferrer, J., Terme, R., Series, C., and Myerson, R.M. (1977) A Method for Serum Octanoate in Hepatic Cirrhosis and Hepatic Encephalopathy, Clin. Chem. 23, 2202-2206.
12. Linscheer, W.G., Blum, A.L., and Platt, R.R. (1970) Transfer of Medium-Chain Fatty Acids from Blood to Spinal Fluid in Patients with Cirrhosis, Gastroenterology 58, 509-515.
13. Carnielli, V.P., Sulkers, E.J., Moretti, C., Wattimena, J.L.D., van Goudoever, J.B., Degenhart, H.J., Zacchello, F., and Sauer, P.J.J. (1994) Conversion of Octanoic Acid into Long-Chain Saturated Fatty Acids in Premature Infants Fed a Formula Containing Medium-Chain Triglycerides, Metabolism 43, 1287-1292.
14. Mok, K.T., Maiz, A., Yamazaki, K., Sobrado, J., Babayan, V.K., Moldawer, L.L., Bistrian, B.R., and Blackburn, G.L. (1984) Structured Medium-Chain and Long Triglyceride Emulsions Are Superior to Physical Mixtures in Sparing Body Protein in the Burned Rat, Metabolism 33, 910-915.
15. Mascioli, E.A., Randall, S., Porter, K.A., Kater, G., Lopes, S., Babayan, V.K., Blackburn, G.L., and Bistrian, B.R. (1991) Thermogenesis from Intravenous Medium-Chain Triglycerides, JPEN 15, 27-31.
16. Seubert, W., and Podack, E.R. (1973) Mechanisms and Physiological Roles of Fatty Acid Chain Elongation in Microcosms and Mitochondria, Mol. Cell Biochem. 1, 29-40.
17. McGee, R., and Spector, A.A. (1975) Fatty Acid Biosynthesis in Ehrlich Cells. The Mechanism of Short-Term Control by Exogenous Free Fatty Acids, J. Biol. Chem. 250, 5419-5425.
18. Maragoudakis, M.E., Kalinsky, H.J., and Lennane, J. (1975) Metabolism of Octanoate and Its Effect on Glucose and Palmitate Utilization by Isolated Fat Cells, Proc. Soc. Exp. Biol. Med. 148, 606-610.
19. Emken, E.A., Adlof, R.O., Rohwedder, W.K., and Gulley, R.M. (1993) Influence of Linoleic Acid on Desaturation and Uptake of Deuterium-Labeled Palmitic and Stearic Acids in Humans, Biochim. Biophys. Acta 1170, 173-181.
20. 14 Palmitic Acid by Rat Intestinal Slices, Proc. Soc. Exp. Biol. Med. 120, 468-472.
21. Christiansen, E.N., Rortveit, T., Norum, K.R., and Thomassen, M.S. (1986) Fatty Acid Chain Elongation in Rat Small Intestine, Biochem. J. 237, 293-295.